AutismKB 2.0

Annotation Detail for CDC42BPG


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Basic Information Top
Gene Symbol:CDC42BPG ( DMPK2,HSMDPKIN,KAPPA-200,MRCKgamma )
Gene Full Name: CDC42 binding protein kinase gamma (DMPK-like)
Band: 11q13.1
Quick LinksEntrez ID:55561; OMIM: NA; Uniprot ID:MRCKG_HUMAN; ENSEMBL ID: ENSG00000171219; HGNC ID: 29829
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult20 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal18 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx2 / 2414582
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8093_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.8 ± 0.95
Basal Forebrain2.62 ± 0.58
Basal Part of Pons2.12 ± 0.61
Cerebellar Cortex2.85 ± 0.73
Cerebellar Nuclei2.65 ± 0.67
Claustrum3.36 ± 1.01
Epithalamus2.05 ± 0.75
Frontal Lobe2.15 ± 0.64
Globus Pallidus2.5 ± 0.41
Hypothalamus2.39 ± 0.59
Insula2.14 ± 0.56
Limbic Lobe2.44 ± 0.74
Mesencephalon2.52 ± 0.72
Myelencephalon2.4 ± 0.7
Occipital Lobe2.45 ± 0.73
Parietal Lobe2.36 ± 0.76
Pontine Tegmentum2.45 ± 0.76
Striatum2.27 ± 0.56
Subthalamus2.71 ± 0.83
Temporal Lobe2.3 ± 0.71
Thalamus2.3 ± 0.59
White Matter2.54 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdc42bpgCBCerebellum2.4
2.75
Cdc42bpgCTXCerebral cortex1.9
1.63
Cdc42bpgHIPHippocampal region2.05
2.25
Cdc42bpgHPFHippocampal formation1.76
1.69
Cdc42bpgHYHypothalamus0.36
0.23
Cdc42bpgLSXLateral septal complex0.94
0.78
Cdc42bpgMBMidbrain0.66
0.76
Cdc42bpgMYMedulla3.64
3.93
Cdc42bpgOLFOlfactory bulb4.08
3.5
Cdc42bpgPPons3.78
3.42
Cdc42bpgPALPallidum1.04
0.89
Cdc42bpgRHPRetrohippocampal region0.86
0.51
Cdc42bpgsAMYStriatum-like amygdalar nuclei2.98
2.72
Cdc42bpgSTRStriatum1.52
1.14
Cdc42bpgSTRdStriatum dorsal region1.41
1.04
Cdc42bpgSTRvStriatum ventral region1.5
0.96
Cdc42bpgTHThalamus0.71
0.62
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00027474 8 110 117 RAETACFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018