AutismKB 2.0

Annotation Detail for PRIM2


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Basic Information Top
Gene Symbol:PRIM2 ( MGC75142,PRIM2A,p58 )
Gene Full Name: primase, DNA, polypeptide 2 (58kDa)
Band: 6p11.2
Quick LinksEntrez ID:5558; OMIM: 176636; Uniprot ID:PRI2_HUMAN; ENSEMBL ID: ENSG00000146143; HGNC ID: 9370
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus15 / 56401226
neonate6 / 31097192
infant1 / 2362042
juvenile4 / 5555671
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor8 / 17290462
gastrointestinal tumor3 / 11936925
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma6 / 7175583
non-neoplasia2 / 9725020
normal84 / 336030724
ovarian tumor6 / 7668278
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites2 / 4001549
bladder2 / 2975767
blood1 / 1234788
bone1 / 7165513
bone marrow2 / 4880140
brain18 / 110098916
cervix3 / 4817162
connective tissue16 / 149255107
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus8 / 20209395
eye4 / 21105418
heart1 / 8962611
intestine3 / 23447212
kidney8 / 21177737
larynx0 / 241450 
liver4 / 20774319
lung0 / 3369740 
lymph2 / 4427045
lymph node1 / 9161010
mammary gland7 / 15327145
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary7 / 10205168
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta4 / 28082514
prostate7 / 18934536
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215708_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.95
Adipocyte6.35
AdrenalCortex7.7
Adrenalgland5.95
Amygdala6.85
Appendix12.9
AtrioventricularNode5.85
BDCA4+_DentriticCells7.1
Bonemarrow8.35
BronchialEpithelialCells6.8
CD105+_Endothelial6.95
CD14+_Monocytes7.8
CD19+_BCells(neg._sel.)8.1
CD33+_Myeloid7.95
CD34+8.55
CD4+_Tcells6.95
CD56+_NKCells7.8
CD71+_EarlyErythroid6.75
CD8+_Tcells7.75
CardiacMyocytes15.9
Caudatenucleus6
Cerebellum5.55
CerebellumPeduncles8.25
CiliaryGanglion5.6
CingulateCortex7.05
Colorectaladenocarcinoma6.55
DorsalRootGanglion8.1
FetalThyroid6.8
Fetalbrain6.3
Fetalliver5.85
Fetallung5.3
GlobusPallidus5.2
Heart10.35
Hypothalamus6.7
Kidney5.85
Leukemia_chronicMyelogenousK-5626.7
Leukemia_promyelocytic-HL-606.05
Leukemialymphoblastic(MOLT-4)5.55
Liver10.35
Lung7.3
Lymphnode5.55
Lymphoma_burkitts(Daudi)9.6
Lymphoma_burkitts(Raji)11.15
MedullaOblongata6
OccipitalLobe5.8
OlfactoryBulb5.15
Ovary5.85
Pancreas6.15
PancreaticIslet7.4
ParietalLobe7.4
Pituitary8
Placenta6.9
Pons6.75
PrefrontalCortex7.95
Prostate7.95
Salivarygland6
SkeletalMuscle8.65
Skin7.35
SmoothMuscle7.9
Spinalcord7.2
SubthalamicNucleus6.35
SuperiorCervicalGanglion14.55
TemporalLobe6.4
Testis5.75
TestisGermCell7.15
TestisIntersitial6.25
TestisLeydigCell7.5
TestisSeminiferousTubule5.65
Thalamus7
Thymus7.2
Thyroid8.05
Tongue7.05
Tonsil7.25
Trachea5.6
TrigeminalGanglion11.8
Uterus5.55
UterusCorpus8.05
WholeBlood7.4
Wholebrain5.3
colon7
pineal_day7.94
pineal_night7.72
retina8.05
small_intestine6.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P282237
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.18 ± 1.1
Basal Forebrain1.69 ± 0.22
Basal Part of Pons1.53 ± 0.37
Cerebellar Cortex2.5 ± 0.33
Cerebellar Nuclei2.23 ± 0.91
Claustrum2.59 ± 0.79
Epithalamus2.08 ± 0.67
Frontal Lobe1.62 ± 0.64
Globus Pallidus1.98 ± 0.49
Hypothalamus1.8 ± 0.79
Insula1.8 ± 0.86
Limbic Lobe1.81 ± 0.67
Mesencephalon2 ± 0.7
Myelencephalon1.86 ± 0.63
Occipital Lobe2.14 ± 0.67
Parietal Lobe1.83 ± 0.88
Pontine Tegmentum1.98 ± 0.92
Striatum1.76 ± 0.96
Subthalamus1.92 ± 0.74
Temporal Lobe1.76 ± 0.63
Thalamus1.75 ± 0.67
White Matter2.27 ± 0.74
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prim2CBCerebellum8.09
8.06
Prim2CTXCerebral cortex0.88
0.74
Prim2HIPHippocampal region1.35
1.39
Prim2HPFHippocampal formation1.11
1.03
Prim2HYHypothalamus0.56
0.42
Prim2LSXLateral septal complex0.8
0.56
Prim2MBMidbrain1.62
2.26
Prim2MYMedulla2.05
2.5
Prim2OLFOlfactory bulb8.78
8.25
Prim2PPons1.52
1.63
Prim2PALPallidum0.55
0.52
Prim2RHPRetrohippocampal region0.7
0.54
Prim2sAMYStriatum-like amygdalar nuclei0.61
0.84
Prim2STRStriatum0.96
0.84
Prim2STRdStriatum dorsal region0.63
0.67
Prim2STRvStriatum ventral region2.08
1.22
Prim2THThalamus0.69
0.64
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00070774 11 186 196 IPFADALDLFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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