AutismKB 2.0

Annotation Detail for OTUD5


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Basic Information Top
Gene Symbol:OTUD5 ( DKFZp761A052,DUBA,MGC104871 )
Gene Full Name: OTU domain containing 5
Band: Xp11.23
Quick LinksEntrez ID:55593; OMIM: 300713; Uniprot ID:OTUD5_HUMAN; ENSEMBL ID: ENSG00000068308; HGNC ID: 25402
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body16 / 70761226
blastocyst5 / 6231980
fetus13 / 56401223
neonate0 / 310970 
infant1 / 2362042
juvenile3 / 5555653
adult115 / 193912159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor8 / 9417884
cervical tumor7 / 34366203
chondrosarcoma12 / 82823144
colorectal tumor10 / 11424687
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor24 / 26384590
glioma6 / 10688356
head and neck tumor21 / 136302154
kidney tumor7 / 68959101
leukemia6 / 9584262
liver tumor6 / 9635962
lung tumor14 / 103127135
lymphoma6 / 7175583
non-neoplasia5 / 9725051
normal147 / 336030743
ovarian tumor7 / 7668291
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer5 / 10268048
retinoblastoma5 / 46356107
skin tumor18 / 124949144
soft tissue/muscle tissue tumor21 / 125191167
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites2 / 4001549
bladder2 / 2975767
blood8 / 12347864
bone10 / 71655139
bone marrow2 / 4880140
brain47 / 110098942
cervix8 / 48171166
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue23 / 215722106
esophagus0 / 202090 
eye21 / 21105499
heart1 / 8962611
intestine17 / 23447272
kidney10 / 21177747
larynx0 / 241450 
liver11 / 20774352
lung23 / 33697468
lymph2 / 4427045
lymph node6 / 9161065
mammary gland11 / 15327171
mouth6 / 6705289
muscle13 / 107715120
nerve0 / 157680 
ovary8 / 10205178
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta4 / 28082514
prostate14 / 18934573
salivary gland13 / 20155645
skin21 / 21057499
spleen4 / 5395274
stomach11 / 96619113
testis10 / 33044230
thymus3 / 8113136
thyroid2 / 4747342
tonsil4 / 16999235
trachea2 / 5241338
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P337550
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.1 ± 0.32
Basal Forebrain10.12 ± 0.17
Basal Part of Pons10.36 ± 0.21
Cerebellar Cortex10.12 ± 0.19
Cerebellar Nuclei10.05 ± 0.3
Claustrum10.18 ± 0.28
Epithalamus9.99 ± 0.23
Frontal Lobe10.23 ± 0.21
Globus Pallidus9.79 ± 0.26
Hypothalamus10.31 ± 0.23
Insula10.33 ± 0.11
Limbic Lobe10.13 ± 0.3
Mesencephalon10.06 ± 0.2
Myelencephalon10.13 ± 0.3
Occipital Lobe9.92 ± 0.31
Parietal Lobe10.2 ± 0.25
Pontine Tegmentum10.06 ± 0.25
Striatum9.95 ± 0.34
Subthalamus10.18 ± 0.11
Temporal Lobe10.29 ± 0.23
Thalamus10.03 ± 0.21
White Matter9.86 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Otud5CBCerebellum37.03
58.42
Otud5CTXCerebral cortex90.16
75.49
Otud5HIPHippocampal region66.55
100
Otud5HPFHippocampal formation72.37
97.08
Otud5HYHypothalamus69.85
64.77
Otud5LSXLateral septal complex45.32
34.75
Otud5MBMidbrain13.1
15.29
Otud5MYMedulla16.23
21.44
Otud5OLFOlfactory bulb100
100
Otud5PPons20.77
29.16
Otud5PALPallidum63.04
61.1
Otud5RHPRetrohippocampal region83.92
78.61
Otud5sAMYStriatum-like amygdalar nuclei100
86.79
Otud5STRStriatum87.65
69.08
Otud5STRdStriatum dorsal region85.32
64.18
Otud5STRvStriatum ventral region100
98.34
Otud5THThalamus28.16
25.06
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064148 17 388 404 ATDWEATNEAIEEQVAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018