AutismKB 2.0

Annotation Detail for KIF21A


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Basic Information Top
Gene Symbol:KIF21A ( CFEOM1,DKFZp779C159,FEOM1,FEOM3A,FLJ20052,KIAA1708 )
Gene Full Name: kinesin family member 21A
Band: 12q12
Quick LinksEntrez ID:55605; OMIM: 608283; Uniprot ID:KI21A_HUMAN; ENSEMBL ID: ENSG00000139116; HGNC ID: 19349
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus21 / 56401237
neonate0 / 310970 
infant3 / 23620127
juvenile9 / 55556161
adult72 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor4 / 34366116
chondrosarcoma0 / 828230 
colorectal tumor13 / 114246113
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor10 / 26384537
glioma3 / 10688328
head and neck tumor8 / 13630258
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal129 / 336030738
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS20 / 125680159
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow1 / 4880120
brain75 / 110098968
cervix4 / 4817183
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye8 / 21105437
heart3 / 8962633
intestine15 / 23447263
kidney14 / 21177766
larynx0 / 241450 
liver1 / 2077434
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth5 / 6705274
muscle2 / 10771518
nerve6 / 15768380
ovary1 / 1020519
pancreas15 / 21481269
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta6 / 28082521
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen2 / 5395237
stomach4 / 9661941
testis6 / 33044218
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P366315
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.43 ± 0.23
Basal Forebrain11.58 ± 0.27
Basal Part of Pons11.88 ± 0.23
Cerebellar Cortex11.6 ± 0.21
Cerebellar Nuclei12.11 ± 0.35
Claustrum11.97 ± 0.4
Epithalamus11.4 ± 0.49
Frontal Lobe11.77 ± 0.36
Globus Pallidus11.69 ± 0.31
Hypothalamus11.87 ± 0.19
Insula11.65 ± 0.18
Limbic Lobe11.68 ± 0.29
Mesencephalon11.8 ± 0.37
Myelencephalon11.69 ± 0.34
Occipital Lobe11.88 ± 0.31
Parietal Lobe11.76 ± 0.29
Pontine Tegmentum11.7 ± 0.36
Striatum11.25 ± 0.32
Subthalamus12.17 ± 0.19
Temporal Lobe11.63 ± 0.23
Thalamus11.8 ± 0.29
White Matter11.2 ± 0.21
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
KI21A_HUMAN_1 11 1 11 MLGAPDESSVR PRIDE
KI21A_HUMAN_804 7 804 810 KRDHQLR PRIDE
PAp00027744 13 226 238 SHAIFTIHVCQTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018