AutismKB 2.0

Annotation Detail for PRR5


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Basic Information Top
Gene Symbol:PRR5 ( FLJ20185,FLJ20185k,PP610,PROTOR-1,PROTOR1 )
Gene Full Name: proline rich 5 (renal)
Band: 22q13.31
Quick LinksEntrez ID:55615; OMIM: 609406; Uniprot ID:PRR5_HUMAN; ENSEMBL ID: ENSG00000186654; HGNC ID: 31682
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor9 / 9417895
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia16 / 95842166
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal116 / 336030734
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood19 / 123478153
bone1 / 7165513
bone marrow0 / 488010 
brain33 / 110098929
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine9 / 23447238
kidney12 / 21177756
larynx1 / 2414541
liver7 / 20774333
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland11 / 15327171
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta31 / 280825110
prostate7 / 18934536
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219168_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.35
Adipocyte5.1
AdrenalCortex4.3
Adrenalgland3.5
Amygdala4.45
Appendix4.2
AtrioventricularNode3.15
BDCA4+_DentriticCells4.7
Bonemarrow4.15
BronchialEpithelialCells4.05
CD105+_Endothelial7.4
CD14+_Monocytes4.5
CD19+_BCells(neg._sel.)6.8
CD33+_Myeloid5.4
CD34+7.75
CD4+_Tcells31.45
CD56+_NKCells45.15
CD71+_EarlyErythroid219.35
CD8+_Tcells26.85
CardiacMyocytes5.2
Caudatenucleus3.75
Cerebellum3.35
CerebellumPeduncles4.7
CiliaryGanglion2.9
CingulateCortex4.2
Colorectaladenocarcinoma4.25
DorsalRootGanglion3.15
FetalThyroid4.05
Fetalbrain4.2
Fetalliver3.85
Fetallung3.5
GlobusPallidus3.05
Heart8.85
Hypothalamus4.55
Kidney3.5
Leukemia_chronicMyelogenousK-5623.75
Leukemia_promyelocytic-HL-603.7
Leukemialymphoblastic(MOLT-4)3.3
Liver7.65
Lung4.65
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.3
Lymphoma_burkitts(Raji)6.35
MedullaOblongata3.75
OccipitalLobe3.75
OlfactoryBulb3.3
Ovary2.75
Pancreas3.35
PancreaticIslet4.4
ParietalLobe4.35
Pituitary4.9
Placenta6.5
Pons3.9
PrefrontalCortex5.3
Prostate4.95
Salivarygland3.3
SkeletalMuscle4.65
Skin3.15
SmoothMuscle4.8
Spinalcord4.45
SubthalamicNucleus3.8
SuperiorCervicalGanglion4.65
TemporalLobe3.8
Testis3.55
TestisGermCell3.55
TestisIntersitial3.5
TestisLeydigCell4.15
TestisSeminiferousTubule3.6
Thalamus4.25
Thymus3.35
Thyroid5.4
Tongue4.05
Tonsil4.05
Trachea3.4
TrigeminalGanglion4.3
Uterus3.45
UterusCorpus3.7
WholeBlood6.6
Wholebrain3.9
colon4.15
pineal_day5.16
pineal_night5.08
retina4.975
small_intestine4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P10890
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.36 ± 0.68
Basal Forebrain12.05 ± 0.24
Basal Part of Pons12.65 ± 0.4
Cerebellar Cortex11.76 ± 0.41
Cerebellar Nuclei12.37 ± 0.37
Claustrum12.25 ± 0.46
Epithalamus11.79 ± 0.35
Frontal Lobe12.25 ± 0.63
Globus Pallidus12.77 ± 0.34
Hypothalamus11.83 ± 0.65
Insula12.13 ± 0.8
Limbic Lobe12.31 ± 0.54
Mesencephalon12.04 ± 0.5
Myelencephalon12.23 ± 0.63
Occipital Lobe12.15 ± 0.55
Parietal Lobe12.11 ± 0.53
Pontine Tegmentum12.1 ± 0.67
Striatum12.55 ± 0.56
Subthalamus11.95 ± 0.53
Temporal Lobe12.17 ± 0.54
Thalamus12.23 ± 0.57
White Matter12.69 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Arhgap8CBCerebellum1.24
3.03
Arhgap8CTXCerebral cortex0.49
0.81
Arhgap8HIPHippocampal region0.11
0.27
Arhgap8HPFHippocampal formation0.13
0.45
Arhgap8HYHypothalamus2.9
5.24
Arhgap8LSXLateral septal complex0.03
0
Arhgap8MBMidbrain0.67
1.48
Arhgap8MYMedulla0.26
0.81
Arhgap8OLFOlfactory bulb1.11
1.71
Arhgap8PPons2.25
5.32
Arhgap8PALPallidum0.14
1.26
Arhgap8RHPRetrohippocampal region0.17
0.85
Arhgap8sAMYStriatum-like amygdalar nuclei0.5
0.54
Arhgap8STRStriatum0.2
0.42
Arhgap8STRdStriatum dorsal region0.13
0.24
Arhgap8STRvStriatum ventral region0.26
0.9
Arhgap8THThalamus0.17
0.19
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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