AutismKB 2.0

Annotation Detail for TRMT1


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Basic Information Top
Gene Symbol:TRMT1 ( FLJ20244,TRM1 )
Gene Full Name: TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)
Band: 19p13.13
Quick LinksEntrez ID:55621; OMIM: 611669; Uniprot ID:TRM1_HUMAN; ENSEMBL ID: ENSG00000104907; HGNC ID: 25980
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst9 / 62319144
fetus71 / 564012125
neonate2 / 3109764
infant20 / 23620846
juvenile25 / 55556449
adult164 / 193912184
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor11 / 94178116
cervical tumor3 / 3436687
chondrosarcoma7 / 8282384
colorectal tumor9 / 11424678
esophageal tumor2 / 17290115
gastrointestinal tumor12 / 119369100
germ cell tumor61 / 263845231
glioma9 / 10688384
head and neck tumor5 / 13630236
kidney tumor10 / 68959145
leukemia12 / 95842125
liver tumor13 / 96359134
lung tumor9 / 10312787
lymphoma12 / 71755167
non-neoplasia15 / 97250154
normal558 / 3360307166
ovarian tumor9 / 76682117
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS72 / 125680572
prostate cancer2 / 10268019
retinoblastoma7 / 46356151
skin tumor8 / 12494964
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland12 / 33197361
ascites6 / 40015149
bladder9 / 29757302
blood11 / 12347889
bone3 / 7165541
bone marrow8 / 48801163
brain297 / 1100989269
cervix5 / 48171103
connective tissue30 / 149255200
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus6 / 20209296
eye16 / 21105475
heart15 / 89626167
intestine50 / 234472213
kidney32 / 211777151
larynx0 / 241450 
liver15 / 20774372
lung30 / 33697489
lymph4 / 4427090
lymph node2 / 9161021
mammary gland14 / 15327191
mouth8 / 67052119
muscle3 / 10771527
nerve0 / 157680 
ovary17 / 102051166
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta24 / 28082585
prostate19 / 189345100
salivary gland1 / 2015549
skin10 / 21057447
spleen50 / 53952926
stomach8 / 9661982
testis49 / 330442148
thymus28 / 81131345
thyroid2 / 4747342
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord2 / 13680146
uterus35 / 232878150
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210463_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts26.4
Adipocyte4.15
AdrenalCortex4.35
Adrenalgland3.55
Amygdala4.4
Appendix4.2
AtrioventricularNode2.7
BDCA4+_DentriticCells46.55
Bonemarrow4.05
BronchialEpithelialCells5.7
CD105+_Endothelial27.7
CD14+_Monocytes20.3
CD19+_BCells(neg._sel.)60.35
CD33+_Myeloid43.95
CD34+95.7
CD4+_Tcells109.9
CD56+_NKCells22.05
CD71+_EarlyErythroid3.85
CD8+_Tcells81.5
CardiacMyocytes5.05
Caudatenucleus3.75
Cerebellum3.4
CerebellumPeduncles4.7
CiliaryGanglion2.85
CingulateCortex4.35
Colorectaladenocarcinoma13.35
DorsalRootGanglion3
FetalThyroid4.15
Fetalbrain4.3
Fetalliver3.1
Fetallung3.5
GlobusPallidus3.1
Heart5.15
Hypothalamus7.35
Kidney2.95
Leukemia_chronicMyelogenousK-56241.35
Leukemia_promyelocytic-HL-607.65
Leukemialymphoblastic(MOLT-4)3.4
Liver4.55
Lung5.1
Lymphnode7.9
Lymphoma_burkitts(Daudi)5.8
Lymphoma_burkitts(Raji)11.3
MedullaOblongata3.8
OccipitalLobe3.35
OlfactoryBulb5.9
Ovary2.75
Pancreas3.35
PancreaticIslet4.35
ParietalLobe4.35
Pituitary4.85
Placenta4.3
Pons3.95
PrefrontalCortex11.8
Prostate4.85
Salivarygland3.25
SkeletalMuscle4.85
Skin3.1
SmoothMuscle4.75
Spinalcord4.45
SubthalamicNucleus3.8
SuperiorCervicalGanglion4.75
TemporalLobe3.85
Testis6.9
TestisGermCell4.15
TestisIntersitial2.8
TestisLeydigCell4.2
TestisSeminiferousTubule4.3
Thalamus4.25
Thymus3.35
Thyroid5.25
Tongue4
Tonsil4.1
Trachea3.45
TrigeminalGanglion4
Uterus13.7
UterusCorpus3.75
WholeBlood4.55
Wholebrain7.5
colon4.15
pineal_day17.04
pineal_night7.56
retina5.025
small_intestine3.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16551_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.02 ± 0.64
Basal Forebrain6.25 ± 0.25
Basal Part of Pons6.74 ± 0.22
Cerebellar Cortex6.48 ± 0.48
Cerebellar Nuclei6.12 ± 0.49
Claustrum5.66 ± 0.57
Epithalamus6.41 ± 0.43
Frontal Lobe6.41 ± 0.49
Globus Pallidus5.55 ± 0.46
Hypothalamus6.19 ± 0.55
Insula6.37 ± 0.42
Limbic Lobe6.27 ± 0.55
Mesencephalon6.03 ± 0.52
Myelencephalon6.25 ± 0.52
Occipital Lobe6.24 ± 0.41
Parietal Lobe6.29 ± 0.5
Pontine Tegmentum6.16 ± 0.51
Striatum5.92 ± 0.45
Subthalamus6.81 ± 0.27
Temporal Lobe6.4 ± 0.45
Thalamus6.32 ± 0.41
White Matter6.31 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trmt1CBCerebellum30.16
43.39
Trmt1CTXCerebral cortex100
100
Trmt1HIPHippocampal region72.28
100
Trmt1HPFHippocampal formation82.8
100
Trmt1HYHypothalamus74.44
58.33
Trmt1LSXLateral septal complex100
92.15
Trmt1MBMidbrain57.55
52.38
Trmt1MYMedulla45.57
50.19
Trmt1OLFOlfactory bulb100
87.65
Trmt1PPons50.44
52.92
Trmt1PALPallidum74.89
62.32
Trmt1RHPRetrohippocampal region100
88.18
Trmt1sAMYStriatum-like amygdalar nuclei89.75
62.91
Trmt1STRStriatum84.08
58.52
Trmt1STRdStriatum dorsal region78.81
54.01
Trmt1STRvStriatum ventral region84.14
58.03
Trmt1THThalamus93.68
77.1
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007559 24 143 166 TAAVGEICEEGLHVLEGLAASGLR Peptide Atlas
TRM1_HUMAN_131 12 131 142 ESENLASGDQPR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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