AutismKB 2.0

Annotation Detail for G2E3


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Basic Information Top
Gene Symbol:G2E3 ( FLJ20333,KIAA1333,PHF7B )
Gene Full Name: G2/M-phase specific E3 ubiquitin protein ligase
Band: 14q12
Quick LinksEntrez ID:55632; OMIM: 611299; Uniprot ID:G2E3_HUMAN; ENSEMBL ID: ENSG00000092140; HGNC ID: 20338
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst4 / 6231964
fetus46 / 56401281
neonate3 / 3109796
infant0 / 236200 
juvenile3 / 5555653
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma5 / 17475286
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor1 / 1142468
esophageal tumor5 / 17290289
gastrointestinal tumor3 / 11936925
germ cell tumor14 / 26384553
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor7 / 9635972
lung tumor0 / 1031270 
lymphoma7 / 7175597
non-neoplasia0 / 972500 
normal178 / 336030752
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor7 / 12494956
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder5 / 29757168
blood1 / 1234788
bone5 / 7165569
bone marrow1 / 4880120
brain50 / 110098945
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus5 / 20209247
eye2 / 2110549
heart5 / 8962655
intestine5 / 23447221
kidney5 / 21177723
larynx0 / 241450 
liver14 / 20774367
lung3 / 3369748
lymph0 / 442700 
lymph node19 / 91610207
mammary gland8 / 15327152
mouth4 / 6705259
muscle6 / 10771555
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland4 / 16585241
placenta14 / 28082549
prostate3 / 18934515
salivary gland2 / 2015599
skin11 / 21057452
spleen0 / 539520 
stomach2 / 9661920
testis52 / 330442157
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord2 / 13680146
uterus11 / 23287847
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P99604
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.85 ± 0.44
Basal Forebrain6.11 ± 0.37
Basal Part of Pons5.56 ± 0.44
Cerebellar Cortex5.9 ± 0.28
Cerebellar Nuclei5.84 ± 0.27
Claustrum5.78 ± 0.32
Epithalamus5.79 ± 0.41
Frontal Lobe5.83 ± 0.33
Globus Pallidus5.68 ± 0.37
Hypothalamus5.96 ± 0.52
Insula5.85 ± 0.24
Limbic Lobe5.94 ± 0.4
Mesencephalon5.87 ± 0.46
Myelencephalon5.92 ± 0.43
Occipital Lobe6.07 ± 0.37
Parietal Lobe5.93 ± 0.4
Pontine Tegmentum5.91 ± 0.5
Striatum6.71 ± 0.38
Subthalamus5.97 ± 0.44
Temporal Lobe5.93 ± 0.38
Thalamus5.84 ± 0.4
White Matter6.75 ± 0.09
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
6030408C04RikCBCerebellum2.07
3.45
6030408C04RikCTXCerebral cortex5.44
3.77
6030408C04RikHIPHippocampal region1.95
1.94
6030408C04RikHPFHippocampal formation1.66
1.67
6030408C04RikHYHypothalamus0.25
0.27
6030408C04RikLSXLateral septal complex0.29
0.3
6030408C04RikMBMidbrain0.64
0.96
6030408C04RikMYMedulla1.94
2.45
6030408C04RikOLFOlfactory bulb6.21
4.23
6030408C04RikPPons0.71
1.38
6030408C04RikPALPallidum0.57
0.57
6030408C04RikRHPRetrohippocampal region1.18
1.35
6030408C04RiksAMYStriatum-like amygdalar nuclei1.29
0.84
6030408C04RikSTRStriatum1.82
1.3
6030408C04RikSTRdStriatum dorsal region2.11
1.61
6030408C04RikSTRvStriatum ventral region1.94
1.06
6030408C04RikTHThalamus3.32
4.24
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018