Annotation Detail for PRKACA
Basic Information Top
| Gene Symbol: | PRKACA ( MGC102831,MGC48865,PKACA ) |
|---|---|
| Gene Full Name: | protein kinase, cAMP-dependent, catalytic, alpha |
| Band: | 19p13.1 |
| Quick Links | Entrez ID:5566; OMIM: 601639; Uniprot ID:KAPCA_HUMAN; ENSEMBL ID: ENSG00000072062; HGNC ID: 9380 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.631630
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 2 / 62319 | 32 | |
| fetus | 51 / 564012 | 90 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 5 / 55556 | 89 | |
| adult | 106 / 1939121 | 54 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 3 / 12794 | 234 |  |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 11 / 94178 | 116 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 1 / 114246 | 8 |  |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 10 / 119369 | 83 | |
| germ cell tumor | 10 / 263845 | 37 | |
| glioma | 8 / 106883 | 74 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 6 / 71755 | 83 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 182 / 3360307 | 54 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 15 / 102680 | 146 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 10 / 125191 | 79 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 4 / 33197 | 120 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 11 / 71655 | 153 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 38 / 1100989 | 34 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 8 / 149255 | 53 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 22 / 211054 | 104 | |
| heart | 8 / 89626 | 89 | |
| intestine | 12 / 234472 | 51 | |
| kidney | 7 / 211777 | 33 | |
| larynx | 0 / 24145 | 0 | |
| liver | 5 / 207743 | 24 | |
| lung | 13 / 336974 | 38 | |
| lymph | 6 / 44270 | 135 | |
| lymph node | 8 / 91610 | 87 | |
| mammary gland | 23 / 153271 | 150 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 5 / 15768 | 317 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 13 / 214812 | 60 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 3 / 16585 | 180 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 18 / 189345 | 95 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 8 / 210574 | 37 | |
| spleen | 9 / 53952 | 166 | |
| stomach | 4 / 96619 | 41 | |
| testis | 17 / 330442 | 51 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 10 / 232878 | 42 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 216234_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6.3 | |
| Adipocyte | 5.6 | |
| AdrenalCortex | 6.25 | |
| Adrenalgland | 4.95 | |
| Amygdala | 6.05 | |
| Appendix | 7 | |
| AtrioventricularNode | 5 | |
| BDCA4+_DentriticCells | 6 | |
| Bonemarrow | 6 | |
| BronchialEpithelialCells | 5.4 | |
| CD105+_Endothelial | 5.85 | |
| CD14+_Monocytes | 6.15 | |
| CD19+_BCells(neg._sel.) | 5.7 | |
| CD33+_Myeloid | 7.35 | |
| CD34+ | 7 | |
| CD4+_Tcells | 5.8 | |
| CD56+_NKCells | 6.15 | |
| CD71+_EarlyErythroid | 5.35 | |
| CD8+_Tcells | 4.85 | |
| CardiacMyocytes | 8.25 | |
| Caudatenucleus | 5.05 | |
| Cerebellum | 5.65 | |
| CerebellumPeduncles | 6.4 | |
| CiliaryGanglion | 8.5 | |
| CingulateCortex | 5.75 | |
| Colorectaladenocarcinoma | 5.65 | |
| DorsalRootGanglion | 5.15 | |
| FetalThyroid | 5.5 | |
| Fetalbrain | 5.7 | |
| Fetalliver | 4.9 | |
| Fetallung | 4.95 | |
| GlobusPallidus | 4.2 | |
| Heart | 12.7 | |
| Hypothalamus | 6.1 | |
| Kidney | 4.8 | |
| Leukemia_chronicMyelogenousK-562 | 5.2 | |
| Leukemia_promyelocytic-HL-60 | 4.95 | |
| Leukemialymphoblastic(MOLT-4) | 4.8 | |
| Liver | 9.45 | |
| Lung | 6.4 | |
| Lymphnode | 4.95 | |
| Lymphoma_burkitts(Daudi) | 7.3 | |
| Lymphoma_burkitts(Raji) | 7.85 | |
| MedullaOblongata | 5.15 | |
| OccipitalLobe | 5.1 | |
| OlfactoryBulb | 4.4 | |
| Ovary | 3.8 | |
| Pancreas | 4.55 | |
| PancreaticIslet | 6.05 | |
| ParietalLobe | 6.05 | |
| Pituitary | 6.6 | |
| Placenta | 5.7 | |
| Pons | 5.35 | |
| PrefrontalCortex | 7 | |
| Prostate | 6.7 | |
| Salivarygland | 4.5 | |
| SkeletalMuscle | 7.25 | |
| Skin | 4.7 | |
| SmoothMuscle | 6.4 | |
| Spinalcord | 6.05 | |
| SubthalamicNucleus | 5.15 | |
| SuperiorCervicalGanglion | 7.25 | |
| TemporalLobe | 5.15 | |
| Testis | 4.85 | |
| TestisGermCell | 4.7 | |
| TestisIntersitial | 4.7 | |
| TestisLeydigCell | 5.65 | |
| TestisSeminiferousTubule | 5.15 | |
| Thalamus | 5.7 | |
| Thymus | 4.5 | |
| Thyroid | 7 | |
| Tongue | 5.85 | |
| Tonsil | 5.55 | |
| Trachea | 4.9 | |
| TrigeminalGanglion | 7.35 | |
| Uterus | 4.6 | |
| UterusCorpus | 5.2 | |
| WholeBlood | 7.2 | |
| Wholebrain | 4.95 | |
| colon | 5.65 | |
| pineal_day | 6.74 | |
| pineal_night | 6.62 | |
| retina | 6.775 | |
| small_intestine | 5.35 | |
- Probe name: A_24_P408206
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.16 ± 0.27 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.87 ± 0.27 | |
| Basal Part of Pons | 7.18 ± 0.36 | |
| Cerebellar Cortex | 6.97 ± 0.37 | |
| Cerebellar Nuclei | 7.08 ± 0.34 | |
| Claustrum | 7.44 ± 0.43 | |
| Epithalamus | 6.32 ± 0.31 | |
| Frontal Lobe | 6.98 ± 0.39 | |
| Globus Pallidus | 6.71 ± 0.36 | |
| Hypothalamus | 7 ± 0.48 | |
| Insula | 6.91 ± 0.25 | |
| Limbic Lobe | 7.19 ± 0.32 | |
| Mesencephalon | 6.98 ± 0.43 | |
| Myelencephalon | 6.94 ± 0.4 | |
| Occipital Lobe | 6.99 ± 0.37 | |
| Parietal Lobe | 7.09 ± 0.44 | |
| Pontine Tegmentum | 6.9 ± 0.46 | |
| Striatum | 6.43 ± 0.33 | |
| Subthalamus | 6.71 ± 0.22 | |
| Temporal Lobe | 7.02 ± 0.36 | |
| Thalamus | 6.93 ± 0.37 | |
| White Matter | 6.27 ± 0.4 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Prkaca | CB | Cerebellum | 100 | |
| 100 | | |||
| Prkaca | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Prkaca | HIP | Hippocampal region | 100 | |
| 100 | | |||
| Prkaca | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Prkaca | HY | Hypothalamus | 100 | |
| 100 | | |||
| Prkaca | LSX | Lateral septal complex | 100 | |
| 100 | | |||
| Prkaca | MB | Midbrain | 100 | |
| 100 | | |||
| Prkaca | MY | Medulla | 71.3 | |
| 100 | | |||
| Prkaca | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Prkaca | P | Pons | 89.18 | |
| 100 | | |||
| Prkaca | PAL | Pallidum | 100 | |
| 100 | | |||
| Prkaca | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Prkaca | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Prkaca | STR | Striatum | 100 | |
| 100 | | |||
| Prkaca | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Prkaca | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Prkaca | TH | Thalamus | 100 | |
| 100 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| KAPCA_HUMAN_29 | 17 | 29 | 45 | KWESPAQNTAHLDQFER | PRIDE |
| KAPCA_HUMAN_8 | 14 | 8 | 21 | KGSEQESVKEFLAK | PRIDE |
| PAp00011800 | 19 | 196 | 214 | TWTLCGTPEYLAPEIILSK | Peptide Atlas |