AutismKB 2.0

Annotation Detail for DDX27


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Basic Information Top
Gene Symbol:DDX27 ( DKFZp667N057,DRS1,FLJ12917,FLJ20596,FLJ22238,MGC1018,MGC163147,PP3241,RHLP,Rrp3p,dJ686N3.1 )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
Band: 20q13.13
Quick LinksEntrez ID:55661; OMIM: NA; Uniprot ID:DDX27_HUMAN; ENSEMBL ID: ENSG00000124228; HGNC ID: 15837
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst7 / 62319112
fetus26 / 56401246
neonate5 / 31097160
infant5 / 23620211
juvenile17 / 55556305
adult175 / 193912190
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor29 / 94178307
cervical tumor3 / 3436687
chondrosarcoma7 / 8282384
colorectal tumor15 / 114246131
esophageal tumor7 / 17290404
gastrointestinal tumor26 / 119369217
germ cell tumor34 / 263845128
glioma21 / 106883196
head and neck tumor10 / 13630273
kidney tumor5 / 6895972
leukemia9 / 9584293
liver tumor23 / 96359238
lung tumor13 / 103127126
lymphoma19 / 71755264
non-neoplasia6 / 9725061
normal233 / 336030769
ovarian tumor5 / 7668265
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS23 / 125680183
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor31 / 124949248
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites12 / 40015299
bladder2 / 2975767
blood12 / 12347897
bone5 / 7165569
bone marrow4 / 4880181
brain97 / 110098988
cervix3 / 4817162
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus7 / 20209346
eye13 / 21105461
heart4 / 8962644
intestine30 / 234472127
kidney20 / 21177794
larynx0 / 241450 
liver32 / 207743154
lung28 / 33697483
lymph15 / 44270338
lymph node2 / 9161021
mammary gland31 / 153271202
mouth8 / 67052119
muscle20 / 107715185
nerve1 / 1576863
ovary5 / 10205148
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta24 / 28082585
prostate4 / 18934521
salivary gland3 / 20155148
skin38 / 210574180
spleen9 / 53952166
stomach14 / 96619144
testis37 / 330442111
thymus6 / 8113173
thyroid1 / 4747321
tonsil1 / 1699958
trachea4 / 5241376
umbilical cord2 / 13680146
uterus20 / 23287885
vascular9 / 51780173
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215693_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts70.15
Adipocyte14.2
AdrenalCortex19.75
Adrenalgland13.25
Amygdala15.35
Appendix15.4
AtrioventricularNode11.1
BDCA4+_DentriticCells195.3
Bonemarrow14.3
BronchialEpithelialCells19.5
CD105+_Endothelial51.25
CD14+_Monocytes42.15
CD19+_BCells(neg._sel.)207.6
CD33+_Myeloid141
CD34+234.05
CD4+_Tcells101.95
CD56+_NKCells223.55
CD71+_EarlyErythroid16.65
CD8+_Tcells70.45
CardiacMyocytes14.55
Caudatenucleus13.25
Cerebellum12.95
CerebellumPeduncles18.4
CiliaryGanglion11.25
CingulateCortex15.5
Colorectaladenocarcinoma37.75
DorsalRootGanglion11.25
FetalThyroid24.8
Fetalbrain14.9
Fetalliver10.4
Fetallung13.1
GlobusPallidus11.25
Heart19.1
Hypothalamus17.85
Kidney12.75
Leukemia_chronicMyelogenousK-56217.05
Leukemia_promyelocytic-HL-6016.2
Leukemialymphoblastic(MOLT-4)16.55
Liver19.6
Lung16.85
Lymphnode20.4
Lymphoma_burkitts(Daudi)32.95
Lymphoma_burkitts(Raji)21.3
MedullaOblongata13.95
OccipitalLobe13.9
OlfactoryBulb12.35
Ovary10.55
Pancreas12.95
PancreaticIslet18.55
ParietalLobe16
Pituitary18.15
Placenta14.3
Pons14.95
PrefrontalCortex18.6
Prostate22.25
Salivarygland12.5
SkeletalMuscle17.6
Skin12.35
SmoothMuscle16.45
Spinalcord16.35
SubthalamicNucleus13.6
SuperiorCervicalGanglion14.7
TemporalLobe13.75
Testis24.8
TestisGermCell17.05
TestisIntersitial16.55
TestisLeydigCell17.45
TestisSeminiferousTubule16.55
Thalamus15.8
Thymus18.1
Thyroid22.3
Tongue16.65
Tonsil18
Trachea12.5
TrigeminalGanglion15.1
Uterus12.7
UterusCorpus13.65
WholeBlood29.8
Wholebrain13.5
colon14.6
pineal_day34.92
pineal_night32.48
retina17.85
small_intestine14.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12239_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.2 ± 0.21
Basal Forebrain8.22 ± 0.18
Basal Part of Pons8.22 ± 0.14
Cerebellar Cortex8.47 ± 0.16
Cerebellar Nuclei8.32 ± 0.25
Claustrum8.24 ± 0.24
Epithalamus8.13 ± 0.24
Frontal Lobe8.23 ± 0.21
Globus Pallidus8.07 ± 0.1
Hypothalamus8.2 ± 0.26
Insula8.3 ± 0.24
Limbic Lobe8.24 ± 0.24
Mesencephalon8.16 ± 0.2
Myelencephalon8.19 ± 0.23
Occipital Lobe8.29 ± 0.23
Parietal Lobe8.26 ± 0.2
Pontine Tegmentum8.24 ± 0.25
Striatum8.01 ± 0.2
Subthalamus8.37 ± 0.03
Temporal Lobe8.27 ± 0.2
Thalamus8.18 ± 0.19
White Matter8.36 ± 0.07
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ddx27CBCerebellum29.66
42.53
Ddx27CTXCerebral cortex100
87.13
Ddx27HIPHippocampal region51.17
69.18
Ddx27HPFHippocampal formation64.59
73.07
Ddx27HYHypothalamus56.7
46.39
Ddx27LSXLateral septal complex55.41
41.52
Ddx27MBMidbrain44.69
39.26
Ddx27MYMedulla60.07
66.66
Ddx27OLFOlfactory bulb83.86
81.3
Ddx27PPons46.23
47.87
Ddx27PALPallidum53.58
50.85
Ddx27RHPRetrohippocampal region89.86
81.96
Ddx27sAMYStriatum-like amygdalar nuclei85.72
73.09
Ddx27STRStriatum65.16
52.78
Ddx27STRdStriatum dorsal region63.69
52.25
Ddx27STRvStriatum ventral region63.85
48.52
Ddx27THThalamus66.6
57.35
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DDX27_HUMAN_765 8 765 772 ASPSFEER PRIDE
PAp00095545 12 257 268 DICACAATGTGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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