AutismKB 2.0

Annotation Detail for SCYL2


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Basic Information Top
Gene Symbol:SCYL2 ( CVAK104,FLJ10074,KIAA1360 )
Gene Full Name: SCY1-like 2 (S. cerevisiae)
Band: 12q23.1
Quick LinksEntrez ID:55681; OMIM: NA; Uniprot ID:SCYL2_HUMAN; ENSEMBL ID: ENSG00000136021; HGNC ID: 19286
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst4 / 6231964
fetus25 / 56401244
neonate2 / 3109764
infant1 / 2362042
juvenile0 / 555560 
adult110 / 193912156
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor10 / 94178106
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor14 / 114246122
esophageal tumor1 / 1729057
gastrointestinal tumor7 / 11936958
germ cell tumor22 / 26384583
glioma1 / 1068839
head and neck tumor9 / 13630266
kidney tumor9 / 68959130
leukemia2 / 9584220
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal140 / 336030741
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer19 / 102680185
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder2 / 2975767
blood5 / 12347840
bone2 / 7165527
bone marrow1 / 4880120
brain44 / 110098939
cervix1 / 4817120
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus1 / 2020949
eye4 / 21105418
heart3 / 8962633
intestine16 / 23447268
kidney18 / 21177784
larynx0 / 241450 
liver9 / 20774343
lung5 / 33697414
lymph0 / 442700 
lymph node12 / 91610130
mammary gland15 / 15327197
mouth7 / 67052104
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate20 / 189345105
salivary gland1 / 2015549
skin4 / 21057418
spleen2 / 5395237
stomach4 / 9661941
testis30 / 33044290
thymus6 / 8113173
thyroid3 / 4747363
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus25 / 232878107
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221220_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.6
Adipocyte3.55
AdrenalCortex3.7
Adrenalgland3
Amygdala3.7
Appendix3.6
AtrioventricularNode2.75
BDCA4+_DentriticCells6.75
Bonemarrow3.5
BronchialEpithelialCells3.55
CD105+_Endothelial3.65
CD14+_Monocytes3.8
CD19+_BCells(neg._sel.)3.9
CD33+_Myeloid4.65
CD34+4.6
CD4+_Tcells4.9
CD56+_NKCells6.65
CD71+_EarlyErythroid3.45
CD8+_Tcells3.5
CardiacMyocytes4.65
Caudatenucleus3.2
Cerebellum2.9
CerebellumPeduncles4.05
CiliaryGanglion2.5
CingulateCortex3.65
Colorectaladenocarcinoma3.55
DorsalRootGanglion2.8
FetalThyroid3.45
Fetalbrain3.6
Fetalliver3.1
Fetallung2.95
GlobusPallidus2.6
Heart4.55
Hypothalamus3.85
Kidney2.9
Leukemia_chronicMyelogenousK-5623.25
Leukemia_promyelocytic-HL-603.2
Leukemialymphoblastic(MOLT-4)2.9
Liver4.7
Lung3.9
Lymphnode3.05
Lymphoma_burkitts(Daudi)4.5
Lymphoma_burkitts(Raji)5
MedullaOblongata3.25
OccipitalLobe3.2
OlfactoryBulb2.85
Ovary2.35
Pancreas2.9
PancreaticIslet3.8
ParietalLobe3.75
Pituitary4.2
Placenta3.7
Pons3.4
PrefrontalCortex4.45
Prostate4.15
Salivarygland2.8
SkeletalMuscle4.15
Skin2.8
SmoothMuscle4.05
Spinalcord3.8
SubthalamicNucleus3.25
SuperiorCervicalGanglion4.15
TemporalLobe3.25
Testis3.05
TestisGermCell2.95
TestisIntersitial2.95
TestisLeydigCell3.55
TestisSeminiferousTubule3.05
Thalamus3.6
Thymus2.8
Thyroid4.45
Tongue3.5
Tonsil3.45
Trachea3
TrigeminalGanglion3.6
Uterus2.95
UterusCorpus3.2
WholeBlood3.9
Wholebrain3.05
colon3.6
pineal_day4.48
pineal_night4.38
retina4.275
small_intestine3.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_745_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.94 ± 0.42
Basal Forebrain5.53 ± 0.3
Basal Part of Pons5.57 ± 0.32
Cerebellar Cortex5.62 ± 0.33
Cerebellar Nuclei5.59 ± 0.35
Claustrum6.1 ± 0.5
Epithalamus5.31 ± 0.18
Frontal Lobe5.56 ± 0.4
Globus Pallidus5.55 ± 0.48
Hypothalamus5.63 ± 0.18
Insula5.54 ± 0.32
Limbic Lobe5.87 ± 0.39
Mesencephalon5.64 ± 0.5
Myelencephalon5.67 ± 0.41
Occipital Lobe5.85 ± 0.4
Parietal Lobe5.67 ± 0.42
Pontine Tegmentum5.65 ± 0.41
Striatum5.55 ± 0.48
Subthalamus5.53 ± 0.13
Temporal Lobe5.65 ± 0.37
Thalamus5.55 ± 0.35
White Matter5.55 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Scyl2CBCerebellum37.51
40.77
Scyl2CTXCerebral cortex35.96
24.05
Scyl2HIPHippocampal region18.61
18.16
Scyl2HPFHippocampal formation18.76
16.15
Scyl2HYHypothalamus3.77
2.84
Scyl2LSXLateral septal complex4.23
2.92
Scyl2MBMidbrain6.3
5.45
Scyl2MYMedulla12.04
11.57
Scyl2OLFOlfactory bulb40.5
46.73
Scyl2PPons8.05
8.07
Scyl2PALPallidum6.39
5.71
Scyl2RHPRetrohippocampal region19.21
13.64
Scyl2sAMYStriatum-like amygdalar nuclei8.47
6.19
Scyl2STRStriatum6.98
5.43
Scyl2STRdStriatum dorsal region6.38
5.12
Scyl2STRvStriatum ventral region9.52
6.98
Scyl2THThalamus16.39
12.94
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00131326 21 324 344 IPFFDDVGAVTLQYFDTLFQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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