AutismKB 2.0

Annotation Detail for TRMU


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Basic Information Top
Gene Symbol:TRMU ( MGC99627,MTO2,MTU1,TRMT,TRMT1,TRNT1 )
Gene Full Name: tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
Band: 22q13.31
Quick LinksEntrez ID:55687; OMIM: 610230; Uniprot ID:MTU1_HUMAN; ENSEMBL ID: ENSG00000100416; HGNC ID: 25481
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213634_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts22.85
Adipocyte13.8
AdrenalCortex21.2
Adrenalgland11.3
Amygdala13.75
Appendix13.45
AtrioventricularNode10.85
BDCA4+_DentriticCells21.95
Bonemarrow13.25
BronchialEpithelialCells13.4
CD105+_Endothelial16.1
CD14+_Monocytes13.95
CD19+_BCells(neg._sel.)14
CD33+_Myeloid16.5
CD34+26.7
CD4+_Tcells30.3
CD56+_NKCells18.4
CD71+_EarlyErythroid12.2
CD8+_Tcells48.75
CardiacMyocytes18.55
Caudatenucleus11.85
Cerebellum10.05
CerebellumPeduncles28.1
CiliaryGanglion9.55
CingulateCortex14.85
Colorectaladenocarcinoma13.45
DorsalRootGanglion10.2
FetalThyroid16.25
Fetalbrain11.4
Fetalliver11.2
Fetallung10.65
GlobusPallidus10.8
Heart19.1
Hypothalamus14.4
Kidney11.35
Leukemia_chronicMyelogenousK-56211.65
Leukemia_promyelocytic-HL-6011.55
Leukemialymphoblastic(MOLT-4)10.75
Liver17.8
Lung14.55
Lymphnode11.2
Lymphoma_burkitts(Daudi)16.95
Lymphoma_burkitts(Raji)40.85
MedullaOblongata11.8
OccipitalLobe11.6
OlfactoryBulb10.75
Ovary8.85
Pancreas10.95
PancreaticIslet14.05
ParietalLobe14.3
Pituitary14.85
Placenta12.95
Pons12.5
PrefrontalCortex16.45
Prostate19.9
Salivarygland10.45
SkeletalMuscle18.9
Skin10.8
SmoothMuscle15.25
Spinalcord14.15
SubthalamicNucleus15.1
SuperiorCervicalGanglion15.25
TemporalLobe14.2
Testis11.1
TestisGermCell10.8
TestisIntersitial11.2
TestisLeydigCell13.5
TestisSeminiferousTubule12.6
Thalamus16.85
Thymus10.45
Thyroid17.35
Tongue20.5
Tonsil12.95
Trachea10.85
TrigeminalGanglion14.6
Uterus12.65
UterusCorpus12.1
WholeBlood14.5
Wholebrain9.2
colon13.65
pineal_day23.52
pineal_night24.68
retina16
small_intestine12.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15092_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.56 ± 0.29
Basal Forebrain4.44 ± 0.29
Basal Part of Pons4.69 ± 0.39
Cerebellar Cortex4.76 ± 0.49
Cerebellar Nuclei4.24 ± 0.33
Claustrum4.29 ± 0.66
Epithalamus4.67 ± 1.09
Frontal Lobe4.72 ± 0.46
Globus Pallidus4.6 ± 0.25
Hypothalamus4.48 ± 0.52
Insula4.55 ± 0.39
Limbic Lobe4.61 ± 0.49
Mesencephalon4.53 ± 0.42
Myelencephalon4.57 ± 0.48
Occipital Lobe4.37 ± 0.4
Parietal Lobe4.55 ± 0.47
Pontine Tegmentum4.46 ± 0.5
Striatum4.19 ± 0.44
Subthalamus4.28 ± 0.4
Temporal Lobe4.65 ± 0.45
Thalamus4.42 ± 0.45
White Matter5.19 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TrmuCBCerebellum5.97
6.32
TrmuCTXCerebral cortex5.87
4.55
TrmuHIPHippocampal region10
8.89
TrmuHPFHippocampal formation6.78
5.83
TrmuHYHypothalamus2.46
1.82
TrmuLSXLateral septal complex1.04
0.76
TrmuMBMidbrain4.66
4.24
TrmuMYMedulla6.97
7.22
TrmuOLFOlfactory bulb6.16
5.42
TrmuPPons4.24
4.08
TrmuPALPallidum1.09
0.83
TrmuRHPRetrohippocampal region1.77
1.82
TrmusAMYStriatum-like amygdalar nuclei0.21
0.16
TrmuSTRStriatum0.59
0.59
TrmuSTRdStriatum dorsal region0.48
0.58
TrmuSTRvStriatum ventral region0.81
0.68
TrmuTHThalamus3.83
3.16
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00499106 15 38 52 NWDSLDEHGVCTADK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018