AutismKB 2.0

Annotation Detail for YEATS2


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Basic Information Top
Gene Symbol:YEATS2 ( FLJ10201,FLJ12841,FLJ13308,FLJ33401,FLJ34335,KIAA1197 )
Gene Full Name: YEATS domain containing 2
Band: 3q27.1
Quick LinksEntrez ID:55689; OMIM: 613373; Uniprot ID:YETS2_HUMAN; ENSEMBL ID: ENSG00000163872; HGNC ID: 25489
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst4 / 6231964
fetus24 / 56401242
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult87 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor4 / 11424635
esophageal tumor4 / 17290231
gastrointestinal tumor4 / 11936933
germ cell tumor27 / 263845102
glioma7 / 10688365
head and neck tumor8 / 13630258
kidney tumor1 / 6895914
leukemia9 / 9584293
liver tumor4 / 9635941
lung tumor7 / 10312767
lymphoma6 / 7175583
non-neoplasia3 / 9725030
normal130 / 336030738
ovarian tumor4 / 7668252
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor11 / 12494988
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood10 / 12347880
bone5 / 7165569
bone marrow5 / 48801102
brain64 / 110098958
cervix1 / 4817120
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus4 / 20209197
eye15 / 21105471
heart3 / 8962633
intestine9 / 23447238
kidney3 / 21177714
larynx1 / 2414541
liver5 / 20774324
lung16 / 33697447
lymph6 / 44270135
lymph node7 / 9161076
mammary gland7 / 15327145
mouth7 / 67052104
muscle11 / 107715102
nerve1 / 1576863
ovary6 / 10205158
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta13 / 28082546
prostate5 / 18934526
salivary gland0 / 201550 
skin13 / 21057461
spleen1 / 5395218
stomach3 / 9661931
testis14 / 33044242
thymus5 / 8113161
thyroid1 / 4747321
tonsil3 / 16999176
trachea1 / 5241319
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221203_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts168.8
Adipocyte29.55
AdrenalCortex37.25
Adrenalgland28
Amygdala63.9
Appendix24.2
AtrioventricularNode22.3
BDCA4+_DentriticCells45
Bonemarrow36.3
BronchialEpithelialCells60.4
CD105+_Endothelial42.1
CD14+_Monocytes49.45
CD19+_BCells(neg._sel.)35.05
CD33+_Myeloid66.35
CD34+148.45
CD4+_Tcells68.1
CD56+_NKCells57.75
CD71+_EarlyErythroid27.95
CD8+_Tcells54.3
CardiacMyocytes52.8
Caudatenucleus42.45
Cerebellum30.95
CerebellumPeduncles48.15
CiliaryGanglion28.2
CingulateCortex76.45
Colorectaladenocarcinoma126.65
DorsalRootGanglion22.6
FetalThyroid42.55
Fetalbrain168.3
Fetalliver27.7
Fetallung39.9
GlobusPallidus38.3
Heart47.75
Hypothalamus97.3
Kidney24.25
Leukemia_chronicMyelogenousK-56230.6
Leukemia_promyelocytic-HL-60107.35
Leukemialymphoblastic(MOLT-4)72.3
Liver37.2
Lung47.45
Lymphnode35.6
Lymphoma_burkitts(Daudi)102.2
Lymphoma_burkitts(Raji)221.65
MedullaOblongata38.55
OccipitalLobe70.6
OlfactoryBulb41.9
Ovary24.25
Pancreas28.2
PancreaticIslet29.65
ParietalLobe52.6
Pituitary50.35
Placenta35.15
Pons39.5
PrefrontalCortex72.2
Prostate51.8
Salivarygland27.35
SkeletalMuscle39.05
Skin29.05
SmoothMuscle55.9
Spinalcord48.55
SubthalamicNucleus40.2
SuperiorCervicalGanglion16.15
TemporalLobe35.7
Testis27.55
TestisGermCell23.7
TestisIntersitial27.75
TestisLeydigCell25.85
TestisSeminiferousTubule28.25
Thalamus60.05
Thymus52.25
Thyroid66.35
Tongue48.4
Tonsil36.65
Trachea25.5
TrigeminalGanglion51.7
Uterus44.45
UterusCorpus23.55
WholeBlood34.3
Wholebrain78.8
colon37.95
pineal_day53.56
pineal_night53.92
retina55.425
small_intestine39.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P376159
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.38 ± 0.83
Basal Forebrain4.01 ± 0.98
Basal Part of Pons3.01 ± 0.29
Cerebellar Cortex4.64 ± 0.51
Cerebellar Nuclei4.1 ± 0.57
Claustrum3.56 ± 0.61
Epithalamus3.22 ± 1.08
Frontal Lobe3.44 ± 0.85
Globus Pallidus4.26 ± 1.11
Hypothalamus3 ± 0.64
Insula3.17 ± 1.08
Limbic Lobe3.43 ± 0.87
Mesencephalon3.7 ± 0.93
Myelencephalon3.77 ± 0.93
Occipital Lobe4.21 ± 0.96
Parietal Lobe3.51 ± 0.85
Pontine Tegmentum3.8 ± 0.87
Striatum3.96 ± 1.18
Subthalamus3.99 ± 0.3
Temporal Lobe3.42 ± 0.74
Thalamus3.92 ± 0.64
White Matter5.41 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Yeats2CBCerebellum4.98
4.17
Yeats2CTXCerebral cortex16
5.81
Yeats2HIPHippocampal region22.65
19.27
Yeats2HPFHippocampal formation21.09
14.17
Yeats2HYHypothalamus5.6
2.28
Yeats2LSXLateral septal complex4.31
1.52
Yeats2MBMidbrain5.1
2.72
Yeats2MYMedulla13.89
8.12
Yeats2OLFOlfactory bulb20.17
7.9
Yeats2PPons8.91
5.53
Yeats2PALPallidum8.62
4.11
Yeats2RHPRetrohippocampal region19.11
9.26
Yeats2sAMYStriatum-like amygdalar nuclei8.77
3.21
Yeats2STRStriatum3.12
1.38
Yeats2STRdStriatum dorsal region2.4
1.13
Yeats2STRvStriatum ventral region2.62
1.22
Yeats2THThalamus15.11
6.94
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
YETS2_HUMAN_101 14 101 114 TCDTMVFNHPAIKK PRIDE
YETS2_HUMAN_1111 20 1111 1130 TEPETPGPSCLSQEGQTAVK PRIDE
YETS2_HUMAN_1131 13 1131 1143 TEESSELGNYVIK PRIDE
YETS2_HUMAN_1178 12 1178 1189 SVEQYYGWNIGK PRIDE
YETS2_HUMAN_1192 6 1192 1197 AAEWQR PRIDE
YETS2_HUMAN_1225 7 1225 1231 HIAHWCR PRIDE
YETS2_HUMAN_165 11 165 175 LSNNMEQRPSR PRIDE
YETS2_HUMAN_281 8 281 288 GWGEFPVR PRIDE
YETS2_HUMAN_394 13 394 406 HTPFYALPSSLER PRIDE
YETS2_HUMAN_407 10 407 416 TPTKMTTSQK PRIDE
YETS2_HUMAN_42 6 42 47 IETIIK PRIDE
YETS2_HUMAN_488 17 488 504 QGTAGSVINNPYVIMDK PRIDE
YETS2_HUMAN_524 17 524 540 ISTASQVSQGTGSPVPK PRIDE
YETS2_HUMAN_620 11 620 630 GGHMIAVSPQK PRIDE
YETS2_HUMAN_631 14 631 644 QVITPGEGIAQSAK PRIDE
YETS2_HUMAN_650 15 650 664 VVGVPVGSALPSTVK PRIDE
YETS2_HUMAN_720 10 720 729 AQVTAAGPQK PRIDE
YETS2_HUMAN_730 29 730 758 SGSQGSVMATLQLPATNLANLANLPPGTK PRIDE
YETS2_HUMAN_901 6 901 906 VISGQK PRIDE
YETS2_HUMAN_948 41 948 988 VAGGVITTATSPAVALSANGPAQQSEGMAPVSSSTVSSVTK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018