AutismKB 2.0

Annotation Detail for FAR2


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Basic Information Top
Gene Symbol:FAR2 ( FLJ10462,MLSTD1,SDR10E2 )
Gene Full Name: fatty acyl CoA reductase 2
Band: 12p11.22
Quick LinksEntrez ID:55711; OMIM: NA; Uniprot ID:FACR2_HUMAN; ENSEMBL ID: ENSG00000064763; HGNC ID: 25531
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220615_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.75
Adipocyte17.5
AdrenalCortex14.15
Adrenalgland11.05
Amygdala14.45
Appendix36.55
AtrioventricularNode9.5
BDCA4+_DentriticCells12.95
Bonemarrow102.45
BronchialEpithelialCells11.2
CD105+_Endothelial12.35
CD14+_Monocytes26.5
CD19+_BCells(neg._sel.)6.8
CD33+_Myeloid48.15
CD34+42.1
CD4+_Tcells8.65
CD56+_NKCells13
CD71+_EarlyErythroid11.6
CD8+_Tcells6.85
CardiacMyocytes15.85
Caudatenucleus13.45
Cerebellum9.95
CerebellumPeduncles14.05
CiliaryGanglion8.5
CingulateCortex16.65
Colorectaladenocarcinoma12.1
DorsalRootGanglion9.4
FetalThyroid14.3
Fetalbrain12.9
Fetalliver12.65
Fetallung8.95
GlobusPallidus9.05
Heart16.35
Hypothalamus24.25
Kidney11.5
Leukemia_chronicMyelogenousK-56219.75
Leukemia_promyelocytic-HL-6010.9
Leukemialymphoblastic(MOLT-4)11.2
Liver16.9
Lung13.6
Lymphnode10.4
Lymphoma_burkitts(Daudi)13.25
Lymphoma_burkitts(Raji)17.15
MedullaOblongata24.65
OccipitalLobe17.7
OlfactoryBulb10.5
Ovary7.7
Pancreas10.1
PancreaticIslet10.75
ParietalLobe13.9
Pituitary13.9
Placenta18.45
Pons25.7
PrefrontalCortex21
Prostate11.1
Salivarygland9.75
SkeletalMuscle17.35
Skin10.1
SmoothMuscle29.1
Spinalcord13.05
SubthalamicNucleus26.6
SuperiorCervicalGanglion27.3
TemporalLobe15
Testis17.2
TestisGermCell15.05
TestisIntersitial16.1
TestisLeydigCell19.5
TestisSeminiferousTubule17.55
Thalamus21.15
Thymus9.75
Thyroid13.75
Tongue12.2
Tonsil12
Trachea8.7
TrigeminalGanglion12.2
Uterus10.25
UterusCorpus11.2
WholeBlood42.2
Wholebrain14.05
colon90.15
pineal_day9.6
pineal_night7.46
retina11.625
small_intestine40
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8676_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.89 ± 0.63
Basal Forebrain6.76 ± 0.3
Basal Part of Pons6.91 ± 0.48
Cerebellar Cortex6.14 ± 0.5
Cerebellar Nuclei6.25 ± 0.81
Claustrum6.81 ± 0.49
Epithalamus5.54 ± 0.9
Frontal Lobe6.87 ± 0.59
Globus Pallidus6.47 ± 1.05
Hypothalamus6.07 ± 0.57
Insula6.72 ± 0.3
Limbic Lobe7.31 ± 0.55
Mesencephalon6.65 ± 0.93
Myelencephalon6.82 ± 0.67
Occipital Lobe7.41 ± 0.53
Parietal Lobe6.98 ± 0.44
Pontine Tegmentum6.67 ± 0.58
Striatum7.93 ± 0.42
Subthalamus7.01 ± 0.13
Temporal Lobe6.87 ± 0.46
Thalamus7.14 ± 0.43
White Matter5.06 ± 1.06
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mlstd1CBCerebellum18.44
68.46
Mlstd1CTXCerebral cortex23.79
18.49
Mlstd1HIPHippocampal region12.09
13.01
Mlstd1HPFHippocampal formation18.89
17.57
Mlstd1HYHypothalamus4.69
3.69
Mlstd1LSXLateral septal complex19.91
14.73
Mlstd1MBMidbrain6.86
5.95
Mlstd1MYMedulla10.52
9.96
Mlstd1OLFOlfactory bulb19.75
18.37
Mlstd1PPons6.47
6.18
Mlstd1PALPallidum5.64
4.54
Mlstd1RHPRetrohippocampal region30.51
23.9
Mlstd1sAMYStriatum-like amygdalar nuclei6.14
4.31
Mlstd1STRStriatum6.59
4.62
Mlstd1STRdStriatum dorsal region5.77
4.15
Mlstd1STRvStriatum ventral region4.4
2.71
Mlstd1THThalamus57.71
52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00499668 14 162 175 HIDEVIYPCPVEPK Peptide Atlas

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018