AutismKB 2.0

Annotation Detail for WDR11


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Basic Information Top
Gene Symbol:WDR11 ( BRWD2,DKFZp434L1715,DR11,FLJ42531,WDR15 )
Gene Full Name: WD repeat domain 11
Band: 10q26.12
Quick LinksEntrez ID:55717; OMIM: 606417; Uniprot ID:WDR11_HUMAN; ENSEMBL ID: ENSG00000120008; HGNC ID: 13831
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst8 / 62319128
fetus35 / 56401262
neonate2 / 3109764
infant0 / 236200 
juvenile2 / 5555635
adult113 / 193912158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor7 / 11424661
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor13 / 26384549
glioma1 / 1068839
head and neck tumor17 / 136302124
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma5 / 7175569
non-neoplasia3 / 9725030
normal217 / 336030764
ovarian tumor8 / 76682104
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer7 / 10268068
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites5 / 40015124
bladder2 / 2975767
blood3 / 12347824
bone5 / 7165569
bone marrow6 / 48801122
brain74 / 110098967
cervix0 / 481710 
connective tissue4 / 14925526
ear1 / 1621261
embryonic tissue18 / 21572283
esophagus1 / 2020949
eye7 / 21105433
heart3 / 8962633
intestine14 / 23447259
kidney11 / 21177751
larynx0 / 241450 
liver6 / 20774328
lung13 / 33697438
lymph5 / 44270112
lymph node14 / 91610152
mammary gland7 / 15327145
mouth9 / 67052134
muscle4 / 10771537
nerve2 / 15768126
ovary8 / 10205178
pancreas14 / 21481265
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta16 / 28082556
prostate14 / 18934573
salivary gland0 / 201550 
skin15 / 21057471
spleen0 / 539520 
stomach1 / 9661910
testis33 / 33044299
thymus1 / 8113112
thyroid10 / 47473210
tonsil0 / 169990 
trachea12 / 52413228
umbilical cord1 / 1368073
uterus24 / 232878103
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218090_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts70.9
Adipocyte9.45
AdrenalCortex11.35
Adrenalgland9
Amygdala57.45
Appendix11
AtrioventricularNode7.7
BDCA4+_DentriticCells83.75
Bonemarrow8.6
BronchialEpithelialCells25.95
CD105+_Endothelial46.75
CD14+_Monocytes48.6
CD19+_BCells(neg._sel.)163.95
CD33+_Myeloid128.15
CD34+79.6
CD4+_Tcells25.5
CD56+_NKCells123
CD71+_EarlyErythroid8.1
CD8+_Tcells34.3
CardiacMyocytes13.95
Caudatenucleus8.6
Cerebellum6.7
CerebellumPeduncles11.15
CiliaryGanglion6.6
CingulateCortex9.4
Colorectaladenocarcinoma39.75
DorsalRootGanglion7.1
FetalThyroid10.75
Fetalbrain19.6
Fetalliver17.05
Fetallung18.2
GlobusPallidus6.5
Heart12.75
Hypothalamus28.75
Kidney8.15
Leukemia_chronicMyelogenousK-56210.65
Leukemia_promyelocytic-HL-6047.05
Leukemialymphoblastic(MOLT-4)10.8
Liver11.9
Lung9.05
Lymphnode27.8
Lymphoma_burkitts(Daudi)13.8
Lymphoma_burkitts(Raji)156.85
MedullaOblongata7.3
OccipitalLobe10.5
OlfactoryBulb9
Ovary7
Pancreas10
PancreaticIslet13.85
ParietalLobe9.8
Pituitary13.65
Placenta16.05
Pons7.45
PrefrontalCortex18.8
Prostate38.9
Salivarygland23.5
SkeletalMuscle11
Skin10.85
SmoothMuscle21.05
Spinalcord78.55
SubthalamicNucleus9.55
SuperiorCervicalGanglion15.45
TemporalLobe7.7
Testis8.55
TestisGermCell9.55
TestisIntersitial7.45
TestisLeydigCell9.75
TestisSeminiferousTubule7.75
Thalamus12.95
Thymus8.3
Thyroid86.95
Tongue8.55
Tonsil10.1
Trachea10.55
TrigeminalGanglion14
Uterus49
UterusCorpus8
WholeBlood29.1
Wholebrain8.95
colon44.75
pineal_day107.6
pineal_night99.52
retina33.475
small_intestine33.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P63929
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.07 ± 0.51
Basal Forebrain6.27 ± 0.18
Basal Part of Pons6.85 ± 0.41
Cerebellar Cortex6.78 ± 0.17
Cerebellar Nuclei6.42 ± 0.28
Claustrum5.73 ± 0.58
Epithalamus6.91 ± 0.5
Frontal Lobe6.47 ± 0.33
Globus Pallidus6.29 ± 0.28
Hypothalamus6.69 ± 0.37
Insula6.42 ± 0.35
Limbic Lobe6.34 ± 0.39
Mesencephalon6.29 ± 0.36
Myelencephalon6.41 ± 0.48
Occipital Lobe6.28 ± 0.42
Parietal Lobe6.32 ± 0.45
Pontine Tegmentum6.32 ± 0.33
Striatum6.28 ± 0.34
Subthalamus6.68 ± 0.18
Temporal Lobe6.49 ± 0.38
Thalamus6.36 ± 0.38
White Matter6.8 ± 0.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Brwd2CBCerebellum5.7
5.14
Brwd2CTXCerebral cortex6.27
2.41
Brwd2HIPHippocampal region9.28
6.72
Brwd2HPFHippocampal formation8.22
5.06
Brwd2HYHypothalamus1.56
0.46
Brwd2LSXLateral septal complex0.1
0.05
Brwd2MBMidbrain3.88
2.01
Brwd2MYMedulla7.5
4.15
Brwd2OLFOlfactory bulb6.97
3.95
Brwd2PPons8.18
4.79
Brwd2PALPallidum2.2
0.88
Brwd2RHPRetrohippocampal region6.37
2.59
Brwd2sAMYStriatum-like amygdalar nuclei3.92
1.11
Brwd2STRStriatum1.48
0.69
Brwd2STRdStriatum dorsal region1.15
0.72
Brwd2STRvStriatum ventral region1.91
0.71
Brwd2THThalamus2.99
1.32
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011690 14 287 300 TGVPFLQVIPCFQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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