AutismKB 2.0

Annotation Detail for TSR1


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Basic Information Top
Gene Symbol:TSR1 ( FLJ10534,KIAA1401,MGC131829 )
Gene Full Name: TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
Band: 17p13.3
Quick LinksEntrez ID:55720; OMIM: 611214; Uniprot ID:TSR1_HUMAN; ENSEMBL ID: ENSG00000167721; HGNC ID: 25542
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst5 / 6231980
fetus31 / 56401254
neonate4 / 31097128
infant1 / 2362042
juvenile8 / 55556143
adult102 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor2 / 3436658
chondrosarcoma11 / 82823132
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor12 / 119369100
germ cell tumor49 / 263845185
glioma4 / 10688337
head and neck tumor19 / 136302139
kidney tumor4 / 6895958
leukemia7 / 9584273
liver tumor5 / 9635951
lung tumor10 / 10312796
lymphoma5 / 7175569
non-neoplasia1 / 9725010
normal205 / 336030761
ovarian tumor9 / 76682117
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer3 / 10268029
retinoblastoma5 / 46356107
skin tumor13 / 124949104
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites10 / 40015249
bladder6 / 29757201
blood15 / 123478121
bone8 / 71655111
bone marrow0 / 488010 
brain97 / 110098988
cervix4 / 4817183
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus1 / 2020949
eye10 / 21105447
heart6 / 8962666
intestine11 / 23447246
kidney14 / 21177766
larynx5 / 24145207
liver14 / 20774367
lung14 / 33697441
lymph2 / 4427045
lymph node2 / 9161021
mammary gland13 / 15327184
mouth14 / 67052208
muscle7 / 10771564
nerve0 / 157680 
ovary7 / 10205168
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta14 / 28082549
prostate5 / 18934526
salivary gland0 / 201550 
skin21 / 21057499
spleen1 / 5395218
stomach0 / 966190 
testis51 / 330442154
thymus9 / 81131110
thyroid1 / 4747321
tonsil1 / 1699958
trachea15 / 52413286
umbilical cord1 / 1368073
uterus17 / 23287872
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221987_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts119.65
Adipocyte10.4
AdrenalCortex16
Adrenalgland10.45
Amygdala10.5
Appendix12.9
AtrioventricularNode17.05
BDCA4+_DentriticCells14.35
Bonemarrow14.7
BronchialEpithelialCells14.1
CD105+_Endothelial34.25
CD14+_Monocytes22.3
CD19+_BCells(neg._sel.)11.75
CD33+_Myeloid23.5
CD34+39.9
CD4+_Tcells13.7
CD56+_NKCells12.4
CD71+_EarlyErythroid12.4
CD8+_Tcells12.3
CardiacMyocytes29.4
Caudatenucleus10.5
Cerebellum9.15
CerebellumPeduncles15.25
CiliaryGanglion15.2
CingulateCortex12.25
Colorectaladenocarcinoma21.85
DorsalRootGanglion13.45
FetalThyroid12.9
Fetalbrain11.25
Fetalliver10.35
Fetallung7.75
GlobusPallidus12.75
Heart24
Hypothalamus10.8
Kidney11.6
Leukemia_chronicMyelogenousK-56210.9
Leukemia_promyelocytic-HL-6016.5
Leukemialymphoblastic(MOLT-4)9.25
Liver16.4
Lung11.5
Lymphnode8.9
Lymphoma_burkitts(Daudi)36.2
Lymphoma_burkitts(Raji)22.3
MedullaOblongata10.45
OccipitalLobe10.55
OlfactoryBulb8.5
Ovary10.95
Pancreas10.4
PancreaticIslet13.75
ParietalLobe15.4
Pituitary13.9
Placenta12.75
Pons12.1
PrefrontalCortex11.3
Prostate11.5
Salivarygland10.2
SkeletalMuscle24
Skin14.85
SmoothMuscle17.35
Spinalcord12.6
SubthalamicNucleus12.55
SuperiorCervicalGanglion23.75
TemporalLobe12
Testis10.8
TestisGermCell8.75
TestisIntersitial13.2
TestisLeydigCell13.6
TestisSeminiferousTubule17.15
Thalamus12.7
Thymus7.8
Thyroid12.6
Tongue16.45
Tonsil12.2
Trachea9.3
TrigeminalGanglion19.25
Uterus8.15
UterusCorpus13.8
WholeBlood10.95
Wholebrain7.6
colon11
pineal_day16.24
pineal_night15.9
retina14.225
small_intestine11.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P941336
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.86 ± 0.36
Basal Forebrain6.99 ± 0.2
Basal Part of Pons7.11 ± 0.21
Cerebellar Cortex6.83 ± 0.14
Cerebellar Nuclei7.09 ± 0.28
Claustrum7.19 ± 0.11
Epithalamus6.94 ± 0.21
Frontal Lobe7.08 ± 0.24
Globus Pallidus7.13 ± 0.33
Hypothalamus7.08 ± 0.27
Insula7.15 ± 0.3
Limbic Lobe6.98 ± 0.26
Mesencephalon7.07 ± 0.28
Myelencephalon6.97 ± 0.26
Occipital Lobe6.8 ± 0.31
Parietal Lobe7.05 ± 0.24
Pontine Tegmentum6.97 ± 0.25
Striatum6.92 ± 0.24
Subthalamus7.17 ± 0.13
Temporal Lobe7.03 ± 0.24
Thalamus6.95 ± 0.22
White Matter6.82 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tsr1CBCerebellum22.68
38.86
Tsr1CTXCerebral cortex67.07
59.24
Tsr1HIPHippocampal region66.04
100
Tsr1HPFHippocampal formation64.7
89.72
Tsr1HYHypothalamus9.39
8.17
Tsr1LSXLateral septal complex11.89
9.24
Tsr1MBMidbrain33.34
32.35
Tsr1MYMedulla26.12
34.3
Tsr1OLFOlfactory bulb34.69
36.23
Tsr1PPons17.2
21.21
Tsr1PALPallidum13.5
14.12
Tsr1RHPRetrohippocampal region62.12
59.89
Tsr1sAMYStriatum-like amygdalar nuclei51.58
48.26
Tsr1STRStriatum26.74
22.2
Tsr1STRdStriatum dorsal region27.66
22.98
Tsr1STRvStriatum ventral region17.1
12.7
Tsr1THThalamus42.46
40.53
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024132 12 610 621 AKEELIFHCGFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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