AutismKB 2.0

Annotation Detail for ASF1B


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Basic Information Top
Gene Symbol:ASF1B ( CIA-II,FLJ10604 )
Gene Full Name: ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
Band: 19p13.12
Quick LinksEntrez ID:55723; OMIM: 609190; Uniprot ID:ASF1B_HUMAN; ENSEMBL ID: ENSG00000105011; HGNC ID: 20996
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst6 / 6231996
fetus22 / 56401239
neonate1 / 3109732
infant6 / 23620254
juvenile10 / 55556179
adult62 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor9 / 34366261
chondrosarcoma2 / 8282324
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor17 / 119369142
germ cell tumor37 / 263845140
glioma11 / 106883102
head and neck tumor2 / 13630214
kidney tumor4 / 6895958
leukemia8 / 9584283
liver tumor3 / 9635931
lung tumor21 / 103127203
lymphoma23 / 71755320
non-neoplasia1 / 9725010
normal117 / 336030734
ovarian tumor4 / 7668252
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS34 / 125680270
prostate cancer6 / 10268058
retinoblastoma5 / 46356107
skin tumor13 / 124949104
soft tissue/muscle tissue tumor27 / 125191215
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites5 / 40015124
bladder1 / 2975733
blood15 / 123478121
bone4 / 7165555
bone marrow0 / 488010 
brain27 / 110098924
cervix11 / 48171228
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus1 / 2020949
eye9 / 21105442
heart1 / 8962611
intestine21 / 23447289
kidney5 / 21177723
larynx0 / 241450 
liver7 / 20774333
lung25 / 33697474
lymph14 / 44270316
lymph node6 / 9161065
mammary gland7 / 15327145
mouth0 / 670520 
muscle12 / 107715111
nerve0 / 157680 
ovary10 / 10205197
pancreas3 / 21481213
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta24 / 28082585
prostate7 / 18934536
salivary gland0 / 201550 
skin13 / 21057461
spleen1 / 5395218
stomach5 / 9661951
testis35 / 330442105
thymus7 / 8113186
thyroid2 / 4747342
tonsil6 / 16999352
trachea0 / 524130 
umbilical cord1 / 1368073
uterus22 / 23287894
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218115_at
Cell line Expression level Expression bar
721_B_lymphoblasts201.35
Adipocyte3.55
AdrenalCortex3.55
Adrenalgland3
Amygdala3.85
Appendix4.1
AtrioventricularNode2.6
BDCA4+_DentriticCells4.05
Bonemarrow7.2
BronchialEpithelialCells3.45
CD105+_Endothelial51.45
CD14+_Monocytes3.9
CD19+_BCells(neg._sel.)3.7
CD33+_Myeloid6.8
CD34+51.7
CD4+_Tcells3.7
CD56+_NKCells6.1
CD71+_EarlyErythroid77.55
CD8+_Tcells3.1
CardiacMyocytes4.85
Caudatenucleus3.25
Cerebellum3.4
CerebellumPeduncles4.15
CiliaryGanglion2.6
CingulateCortex3.7
Colorectaladenocarcinoma67.65
DorsalRootGanglion2.85
FetalThyroid3.9
Fetalbrain3.6
Fetalliver8.7
Fetallung3.05
GlobusPallidus2.75
Heart4.5
Hypothalamus4.05
Kidney2.8
Leukemia_chronicMyelogenousK-56252.8
Leukemia_promyelocytic-HL-6032.2
Leukemialymphoblastic(MOLT-4)177.7
Liver5.05
Lung4
Lymphnode3.1
Lymphoma_burkitts(Daudi)54.45
Lymphoma_burkitts(Raji)6.6
MedullaOblongata4.5
OccipitalLobe3.15
OlfactoryBulb2.95
Ovary2.45
Pancreas2.9
PancreaticIslet3.9
ParietalLobe3.9
Pituitary4.3
Placenta3.9
Pons3.5
PrefrontalCortex4.45
Prostate4.35
Salivarygland2.95
SkeletalMuscle4.15
Skin2.7
SmoothMuscle4.1
Spinalcord3.8
SubthalamicNucleus3.35
SuperiorCervicalGanglion5.85
TemporalLobe3.3
Testis16.65
TestisGermCell20.9
TestisIntersitial4.8
TestisLeydigCell6.65
TestisSeminiferousTubule14.25
Thalamus3.6
Thymus35
Thyroid4.5
Tongue3.55
Tonsil4.05
Trachea3
TrigeminalGanglion4.55
Uterus3.05
UterusCorpus3.2
WholeBlood9.25
Wholebrain3.1
colon3.9
pineal_day4.58
pineal_night4.24
retina4.425
small_intestine3.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5921_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.04 ± 1.01
Basal Forebrain1.56 ± 0.19
Basal Part of Pons1.31 ± 0.41
Cerebellar Cortex1.44 ± 0.73
Cerebellar Nuclei1.87 ± 0.72
Claustrum2.48 ± 0.86
Epithalamus1.29 ± 0.69
Frontal Lobe1.43 ± 0.61
Globus Pallidus2.25 ± 0.33
Hypothalamus1.67 ± 0.65
Insula1.46 ± 0.5
Limbic Lobe1.59 ± 0.66
Mesencephalon1.75 ± 0.71
Myelencephalon1.62 ± 0.68
Occipital Lobe1.59 ± 0.55
Parietal Lobe1.65 ± 0.8
Pontine Tegmentum1.65 ± 0.66
Striatum1.72 ± 0.46
Subthalamus1.73 ± 0.63
Temporal Lobe1.49 ± 0.62
Thalamus1.58 ± 0.57
White Matter2.13 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Asf1bCBCerebellum0.64
0.96
Asf1bCTXCerebral cortex0.31
0.37
Asf1bHIPHippocampal region0.5
0.44
Asf1bHPFHippocampal formation1.07
1.02
Asf1bHYHypothalamus0.37
0.78
Asf1bLSXLateral septal complex0.26
0.24
Asf1bMBMidbrain0.36
1.01
Asf1bMYMedulla0.7
1.13
Asf1bOLFOlfactory bulb1.93
2.18
Asf1bPPons0.78
1.31
Asf1bPALPallidum0.14
0.45
Asf1bRHPRetrohippocampal region2.31
2.08
Asf1bsAMYStriatum-like amygdalar nuclei0.05
0.03
Asf1bSTRStriatum0.09
0.15
Asf1bSTRdStriatum dorsal region0.06
0.15
Asf1bSTRvStriatum ventral region0.09
0.19
Asf1bTHThalamus0.2
0.56
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00080227 15 109 123 VGYYVNNEYLNPELR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018