AutismKB 2.0

Annotation Detail for CARKD


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Basic Information Top
Gene Symbol:CARKD ( FLJ10769,FLJ34548,FLJ52550,LP3298 )
Gene Full Name: carbohydrate kinase domain containing
Band: 13q34
Quick LinksEntrez ID:55739; OMIM: NA; Uniprot ID:CARKD_HUMAN; ENSEMBL ID: ENSG00000213995; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus84 / 564012148
neonate6 / 31097192
infant2 / 2362084
juvenile5 / 5555689
adult165 / 193912185
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor3 / 3436687
chondrosarcoma6 / 8282372
colorectal tumor12 / 114246105
esophageal tumor3 / 17290173
gastrointestinal tumor10 / 11936983
germ cell tumor36 / 263845136
glioma12 / 106883112
head and neck tumor42 / 136302308
kidney tumor7 / 68959101
leukemia5 / 9584252
liver tumor23 / 96359238
lung tumor9 / 10312787
lymphoma2 / 7175527
non-neoplasia10 / 97250102
normal475 / 3360307141
ovarian tumor7 / 7668291
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS21 / 125680167
prostate cancer14 / 102680136
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland8 / 33197240
ascites6 / 40015149
bladder2 / 2975767
blood7 / 12347856
bone7 / 7165597
bone marrow2 / 4880140
brain260 / 1100989236
cervix3 / 4817162
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus3 / 20209148
eye17 / 21105480
heart13 / 89626145
intestine35 / 234472149
kidney27 / 211777127
larynx4 / 24145165
liver29 / 207743139
lung42 / 336974124
lymph1 / 4427022
lymph node15 / 91610163
mammary gland12 / 15327178
mouth38 / 67052566
muscle6 / 10771555
nerve1 / 1576863
ovary8 / 10205178
pancreas25 / 214812116
parathyroid4 / 20539194
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta12 / 28082542
prostate27 / 189345142
salivary gland2 / 2015599
skin16 / 21057475
spleen17 / 53952315
stomach7 / 9661972
testis44 / 330442133
thymus27 / 81131332
thyroid2 / 4747342
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord1 / 1368073
uterus37 / 232878158
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217940_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts259.75
Adipocyte13.7
AdrenalCortex80.15
Adrenalgland91.4
Amygdala171.25
Appendix5.45
AtrioventricularNode3.3
BDCA4+_DentriticCells208.1
Bonemarrow4.8
BronchialEpithelialCells11
CD105+_Endothelial37.2
CD14+_Monocytes63.45
CD19+_BCells(neg._sel.)111.2
CD33+_Myeloid90.5
CD34+123.05
CD4+_Tcells239.9
CD56+_NKCells98.7
CD71+_EarlyErythroid16.25
CD8+_Tcells222.55
CardiacMyocytes13.65
Caudatenucleus55.15
Cerebellum53.8
CerebellumPeduncles78.45
CiliaryGanglion3.05
CingulateCortex43.45
Colorectaladenocarcinoma126.15
DorsalRootGanglion3.7
FetalThyroid30.75
Fetalbrain133
Fetalliver10.25
Fetallung58.4
GlobusPallidus22.25
Heart6.8
Hypothalamus143.5
Kidney32.65
Leukemia_chronicMyelogenousK-56216.4
Leukemia_promyelocytic-HL-603.3
Leukemialymphoblastic(MOLT-4)34.15
Liver35.2
Lung93.25
Lymphnode34.15
Lymphoma_burkitts(Daudi)6.95
Lymphoma_burkitts(Raji)37.25
MedullaOblongata39.6
OccipitalLobe76.95
OlfactoryBulb66.5
Ovary25.5
Pancreas106.65
PancreaticIslet72.8
ParietalLobe26.8
Pituitary60
Placenta104.55
Pons10.15
PrefrontalCortex155.6
Prostate165
Salivarygland8.95
SkeletalMuscle8
Skin5
SmoothMuscle25.25
Spinalcord104.5
SubthalamicNucleus42
SuperiorCervicalGanglion5.25
TemporalLobe35.75
Testis107.8
TestisGermCell239.95
TestisIntersitial39
TestisLeydigCell21.6
TestisSeminiferousTubule45.5
Thalamus97.55
Thymus50.25
Thyroid234.35
Tongue4.9
Tonsil8.9
Trachea13.4
TrigeminalGanglion4.3
Uterus79.5
UterusCorpus14.2
WholeBlood7.8
Wholebrain189.3
colon28.65
pineal_day228.5
pineal_night214.34
retina167.675
small_intestine21.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10826_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.42 ± 0.77
Basal Forebrain4.32 ± 0.47
Basal Part of Pons4.65 ± 0.57
Cerebellar Cortex4.9 ± 0.52
Cerebellar Nuclei4.55 ± 0.55
Claustrum4.56 ± 0.82
Epithalamus3.8 ± 0.69
Frontal Lobe4.23 ± 0.63
Globus Pallidus4.95 ± 0.67
Hypothalamus3.98 ± 0.99
Insula4.29 ± 0.54
Limbic Lobe4.28 ± 0.55
Mesencephalon4.38 ± 0.73
Myelencephalon4.41 ± 0.71
Occipital Lobe4.6 ± 0.64
Parietal Lobe4.5 ± 0.82
Pontine Tegmentum4.32 ± 0.67
Striatum4.49 ± 0.69
Subthalamus4.37 ± 0.54
Temporal Lobe4.28 ± 0.54
Thalamus4.39 ± 0.56
White Matter4.61 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
0710008K08RikCBCerebellum68.9
100
0710008K08RikCTXCerebral cortex100
100
0710008K08RikHIPHippocampal region97.37
100
0710008K08RikHPFHippocampal formation100
100
0710008K08RikHYHypothalamus80.02
72.91
0710008K08RikLSXLateral septal complex100
100
0710008K08RikMBMidbrain88.47
89.34
0710008K08RikMYMedulla85.33
100
0710008K08RikOLFOlfactory bulb100
100
0710008K08RikPPons82.94
95.84
0710008K08RikPALPallidum87.5
88.85
0710008K08RikRHPRetrohippocampal region100
100
0710008K08RiksAMYStriatum-like amygdalar nuclei100
85.18
0710008K08RikSTRStriatum100
97.48
0710008K08RikSTRdStriatum dorsal region100
93.85
0710008K08RikSTRvStriatum ventral region100
100
0710008K08RikTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003824 23 76 98 IGVVGGCQEYTGAPYFAAISALK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018