AutismKB 2.0

Annotation Detail for NUP133


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Basic Information Top
Gene Symbol:NUP133 ( FLJ10814,MGC21133,hNUP133 )
Gene Full Name: nucleoporin 133kDa
Band: 1q42.13
Quick LinksEntrez ID:55746; OMIM: 607613; Uniprot ID:NU133_HUMAN; ENSEMBL ID: ENSG00000069248; HGNC ID: 18016
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus72 / 564012127
neonate1 / 3109732
infant1 / 2362042
juvenile0 / 555560 
adult191 / 193912198
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma6 / 8282372
colorectal tumor14 / 114246122
esophageal tumor2 / 17290115
gastrointestinal tumor9 / 11936975
germ cell tumor47 / 263845178
glioma1 / 1068839
head and neck tumor27 / 136302198
kidney tumor10 / 68959145
leukemia7 / 9584273
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma4 / 7175555
non-neoplasia2 / 9725020
normal308 / 336030791
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer7 / 10268068
retinoblastoma3 / 4635664
skin tumor5 / 12494940
soft tissue/muscle tissue tumor42 / 125191335
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites3 / 4001574
bladder1 / 2975733
blood4 / 12347832
bone9 / 71655125
bone marrow6 / 48801122
brain156 / 1100989141
cervix3 / 4817162
connective tissue44 / 149255294
ear4 / 16212246
embryonic tissue14 / 21572264
esophagus2 / 2020998
eye12 / 21105456
heart5 / 8962655
intestine20 / 23447285
kidney13 / 21177761
larynx4 / 24145165
liver6 / 20774328
lung14 / 33697441
lymph0 / 442700 
lymph node13 / 91610141
mammary gland4 / 15327126
mouth20 / 67052298
muscle5 / 10771546
nerve1 / 1576863
ovary0 / 1020510 
pancreas16 / 21481274
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta23 / 28082581
prostate9 / 18934547
salivary gland2 / 2015599
skin7 / 21057433
spleen0 / 539520 
stomach7 / 9661972
testis71 / 330442214
thymus7 / 8113186
thyroid4 / 4747384
tonsil0 / 169990 
trachea22 / 52413419
umbilical cord0 / 136800 
uterus30 / 232878128
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202184_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts158.1
Adipocyte10.25
AdrenalCortex10.15
Adrenalgland5.05
Amygdala38.5
Appendix17.35
AtrioventricularNode10.45
BDCA4+_DentriticCells74.95
Bonemarrow7.3
BronchialEpithelialCells14.3
CD105+_Endothelial207.2
CD14+_Monocytes34.5
CD19+_BCells(neg._sel.)22.8
CD33+_Myeloid38.8
CD34+298.65
CD4+_Tcells17.7
CD56+_NKCells91.3
CD71+_EarlyErythroid31.25
CD8+_Tcells47.2
CardiacMyocytes16.05
Caudatenucleus11.65
Cerebellum6.3
CerebellumPeduncles13.65
CiliaryGanglion7.4
CingulateCortex11
Colorectaladenocarcinoma13
DorsalRootGanglion10.8
FetalThyroid28.2
Fetalbrain16.65
Fetalliver17.15
Fetallung11.45
GlobusPallidus9.15
Heart9.25
Hypothalamus39
Kidney5.9
Leukemia_chronicMyelogenousK-56262.5
Leukemia_promyelocytic-HL-6029.15
Leukemialymphoblastic(MOLT-4)39.65
Liver14.75
Lung9.95
Lymphnode14.15
Lymphoma_burkitts(Daudi)32
Lymphoma_burkitts(Raji)16
MedullaOblongata13.15
OccipitalLobe11.35
OlfactoryBulb14.5
Ovary7.35
Pancreas8.6
PancreaticIslet10.5
ParietalLobe11.95
Pituitary17.2
Placenta19.65
Pons10.55
PrefrontalCortex29.25
Prostate26.5
Salivarygland8.6
SkeletalMuscle12.8
Skin8.4
SmoothMuscle11.75
Spinalcord14.25
SubthalamicNucleus10
SuperiorCervicalGanglion13.5
TemporalLobe15.75
Testis8
TestisGermCell24.65
TestisIntersitial8.9
TestisLeydigCell11.75
TestisSeminiferousTubule7.05
Thalamus11.35
Thymus9.8
Thyroid62
Tongue10.95
Tonsil9.1
Trachea8.85
TrigeminalGanglion12.1
Uterus28.4
UterusCorpus9.85
WholeBlood19.15
Wholebrain9.35
colon11.1
pineal_day131.2
pineal_night102.38
retina16.225
small_intestine10.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15297_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.69 ± 0.26
Basal Forebrain6.73 ± 0.04
Basal Part of Pons6.85 ± 0.22
Cerebellar Cortex6.87 ± 0.22
Cerebellar Nuclei6.74 ± 0.21
Claustrum6.48 ± 0.32
Epithalamus6.69 ± 0.25
Frontal Lobe6.73 ± 0.27
Globus Pallidus6.81 ± 0.31
Hypothalamus6.85 ± 0.16
Insula6.65 ± 0.23
Limbic Lobe6.67 ± 0.32
Mesencephalon6.65 ± 0.3
Myelencephalon6.68 ± 0.3
Occipital Lobe6.64 ± 0.3
Parietal Lobe6.71 ± 0.24
Pontine Tegmentum6.72 ± 0.29
Striatum6.57 ± 0.32
Subthalamus6.68 ± 0.23
Temporal Lobe6.77 ± 0.23
Thalamus6.71 ± 0.3
White Matter7.58 ± 0.08
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nup133CBCerebellum0
0
Nup133CTXCerebral cortex0
0
Nup133HIPHippocampal region0
0
Nup133HPFHippocampal formation0
0
Nup133HYHypothalamus0
0
Nup133LSXLateral septal complex0
0
Nup133MBMidbrain0
0
Nup133MYMedulla0
0
Nup133OLFOlfactory bulb0
0
Nup133PPons0
0
Nup133PALPallidum0
0
Nup133RHPRetrohippocampal region0
0
Nup133sAMYStriatum-like amygdalar nuclei0
0
Nup133STRStriatum0
0
Nup133STRdStriatum dorsal region0
0
Nup133STRvStriatum ventral region0
0
Nup133THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NU133_HUMAN_1 9 1 9 MFPAAPSPR PRIDE
NU133_HUMAN_18 13 18 30 GPLAGLGPGSTPR PRIDE
NU133_HUMAN_240 18 240 257 IHQHILPQGQGMLSGIGR PRIDE
NU133_HUMAN_35 20 35 54 KGLPLGSAVSSPVLFSPVGR PRIDE
NU133_HUMAN_36 19 36 54 GLPLGSAVSSPVLFSPVGR PRIDE
NU133_HUMAN_949 14 949 962 AHATLLGLANMETR PRIDE
PAp00039395 17 607 623 AHSFLMDFIHQVGLFGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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