AutismKB 2.0

Annotation Detail for AGK


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Basic Information Top
Gene Symbol:AGK ( FLJ10842,MULK )
Gene Full Name: acylglycerol kinase
Band: 7q34
Quick LinksEntrez ID:55750; OMIM: 610345; Uniprot ID:AGK_HUMAN; ENSEMBL ID: ENSG00000006530; HGNC ID: 21869
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus28 / 56401249
neonate6 / 31097192
infant1 / 2362042
juvenile3 / 5555653
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma3 / 17475171
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor15 / 26384556
glioma7 / 10688365
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor7 / 10312767
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal135 / 336030740
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor11 / 12494988
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder3 / 29757100
blood3 / 12347824
bone0 / 716550 
bone marrow1 / 4880120
brain63 / 110098957
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus1 / 2020949
eye3 / 21105414
heart3 / 8962633
intestine7 / 23447229
kidney12 / 21177756
larynx1 / 2414541
liver6 / 20774328
lung16 / 33697447
lymph1 / 4427022
lymph node4 / 9161043
mammary gland8 / 15327152
mouth2 / 6705229
muscle2 / 10771518
nerve1 / 1576863
ovary5 / 10205148
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate5 / 18934526
salivary gland0 / 201550 
skin19 / 21057490
spleen2 / 5395237
stomach1 / 9661910
testis12 / 33044236
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218568_at
Cell line Expression level Expression bar
721_B_lymphoblasts61.7
Adipocyte4.8
AdrenalCortex5.55
Adrenalgland4.9
Amygdala5.85
Appendix7.9
AtrioventricularNode4.2
BDCA4+_DentriticCells11.15
Bonemarrow5.15
BronchialEpithelialCells5.2
CD105+_Endothelial6.25
CD14+_Monocytes5.35
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid6.7
CD34+7.3
CD4+_Tcells8.2
CD56+_NKCells61.4
CD71+_EarlyErythroid4.7
CD8+_Tcells19.15
CardiacMyocytes7.45
Caudatenucleus4.5
Cerebellum4.1
CerebellumPeduncles5.8
CiliaryGanglion3.9
CingulateCortex5.25
Colorectaladenocarcinoma4.95
DorsalRootGanglion4.25
FetalThyroid4.95
Fetalbrain6.35
Fetalliver4.4
Fetallung3.9
GlobusPallidus3.85
Heart6.85
Hypothalamus5.45
Kidney4.2
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.5
Leukemialymphoblastic(MOLT-4)5.15
Liver7.65
Lung5.45
Lymphnode4.15
Lymphoma_burkitts(Daudi)7.05
Lymphoma_burkitts(Raji)7.3
MedullaOblongata4.6
OccipitalLobe4.5
OlfactoryBulb3.9
Ovary3.4
Pancreas4.35
PancreaticIslet5.45
ParietalLobe5.45
Pituitary5.9
Placenta5.1
Pons4.85
PrefrontalCortex9.75
Prostate5.9
Salivarygland4.05
SkeletalMuscle7.75
Skin4.1
SmoothMuscle5.6
Spinalcord5.35
SubthalamicNucleus6
SuperiorCervicalGanglion6.65
TemporalLobe4.65
Testis4.6
TestisGermCell4.05
TestisIntersitial4.15
TestisLeydigCell5.15
TestisSeminiferousTubule4.25
Thalamus5.2
Thymus4.55
Thyroid6.15
Tongue5.1
Tonsil4.9
Trachea4.2
TrigeminalGanglion5.95
Uterus4
UterusCorpus4.95
WholeBlood5.35
Wholebrain7.2
colon5.7
pineal_day6.32
pineal_night6.02
retina6.125
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7992_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.63 ± 0.83
Basal Forebrain2.92 ± 0.48
Basal Part of Pons3.45 ± 0.74
Cerebellar Cortex3.51 ± 0.52
Cerebellar Nuclei3.28 ± 0.5
Claustrum3.54 ± 0.72
Epithalamus3.2 ± 0.49
Frontal Lobe3.39 ± 0.54
Globus Pallidus2.62 ± 0.73
Hypothalamus3.15 ± 0.32
Insula3.21 ± 0.74
Limbic Lobe3.42 ± 0.53
Mesencephalon3.45 ± 0.71
Myelencephalon3.33 ± 0.6
Occipital Lobe3.39 ± 0.78
Parietal Lobe3.46 ± 0.59
Pontine Tegmentum3.37 ± 0.66
Striatum2.97 ± 0.66
Subthalamus3.54 ± 0.95
Temporal Lobe3.43 ± 0.59
Thalamus3.34 ± 0.72
White Matter2.79 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MulkCBCerebellum21.48
23.41
MulkCTXCerebral cortex81.96
66.75
MulkHIPHippocampal region45.54
73.39
MulkHPFHippocampal formation59.84
72.41
MulkHYHypothalamus20.26
16.33
MulkLSXLateral septal complex19.18
14
MulkMBMidbrain36.7
35.21
MulkMYMedulla37.08
38.56
MulkOLFOlfactory bulb63.4
54.76
MulkPPons30.76
32.79
MulkPALPallidum38.2
36.92
MulkRHPRetrohippocampal region83.56
73.74
MulksAMYStriatum-like amygdalar nuclei47.42
35.83
MulkSTRStriatum47.29
35.7
MulkSTRdStriatum dorsal region48.05
36.48
MulkSTRvStriatum ventral region55.19
40.22
MulkTHThalamus33.08
32.03
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000137 22 41 62 AACQEAQVFGNQLIPPNAQVKK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018