AutismKB 2.0

Annotation Detail for INTS9


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Basic Information Top
Gene Symbol:INTS9 ( CPSF2L,FLJ10871,INT9,RC74 )
Gene Full Name: integrator complex subunit 9
Band: 8p21.1
Quick LinksEntrez ID:55756; OMIM: 611352; Uniprot ID:INT9_HUMAN; ENSEMBL ID: ENSG00000104299; HGNC ID: 25592
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus14 / 56401224
neonate2 / 3109764
infant2 / 2362084
juvenile3 / 5555653
adult71 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma3 / 8282336
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor14 / 26384553
glioma4 / 10688337
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma29 / 71755404
non-neoplasia1 / 9725010
normal99 / 336030729
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor9 / 12494972
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood7 / 12347856
bone0 / 716550 
bone marrow5 / 48801102
brain33 / 110098929
cervix5 / 48171103
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye14 / 21105466
heart0 / 896260 
intestine9 / 23447238
kidney7 / 21177733
larynx1 / 2414541
liver3 / 20774314
lung16 / 33697447
lymph25 / 44270564
lymph node3 / 9161032
mammary gland5 / 15327132
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta7 / 28082524
prostate4 / 18934521
salivary gland0 / 201550 
skin12 / 21057456
spleen2 / 5395237
stomach1 / 9661910
testis12 / 33044236
thymus2 / 8113124
thyroid0 / 474730 
tonsil2 / 16999117
trachea2 / 5241338
umbilical cord0 / 136800 
uterus12 / 23287851
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203941_at
Cell line Expression level Expression bar
721_B_lymphoblasts19.9
Adipocyte3.2
AdrenalCortex3.3
Adrenalgland3.5
Amygdala3.4
Appendix3.2
AtrioventricularNode2.35
BDCA4+_DentriticCells11.85
Bonemarrow3.15
BronchialEpithelialCells3.25
CD105+_Endothelial5
CD14+_Monocytes8.6
CD19+_BCells(neg._sel.)8.2
CD33+_Myeloid11.1
CD34+11.85
CD4+_Tcells9
CD56+_NKCells10
CD71+_EarlyErythroid3
CD8+_Tcells5.6
CardiacMyocytes3.95
Caudatenucleus2.85
Cerebellum2.6
CerebellumPeduncles3.6
CiliaryGanglion2.15
CingulateCortex3.25
Colorectaladenocarcinoma3.25
DorsalRootGanglion2.4
FetalThyroid3.15
Fetalbrain3.25
Fetalliver2.75
Fetallung2.7
GlobusPallidus2.3
Heart4.1
Hypothalamus3.55
Kidney2.55
Leukemia_chronicMyelogenousK-5627.7
Leukemia_promyelocytic-HL-602.85
Leukemialymphoblastic(MOLT-4)3.6
Liver4.15
Lung3.5
Lymphnode3.1
Lymphoma_burkitts(Daudi)4.1
Lymphoma_burkitts(Raji)4.4
MedullaOblongata2.95
OccipitalLobe2.85
OlfactoryBulb2.5
Ovary2.1
Pancreas2.5
PancreaticIslet3.4
ParietalLobe3.35
Pituitary3.8
Placenta3.4
Pons3
PrefrontalCortex4.1
Prostate3.8
Salivarygland2.5
SkeletalMuscle3.6
Skin2.45
SmoothMuscle3.6
Spinalcord3.45
SubthalamicNucleus2.9
SuperiorCervicalGanglion3.55
TemporalLobe2.9
Testis7
TestisGermCell3.7
TestisIntersitial2.7
TestisLeydigCell3.2
TestisSeminiferousTubule2.8
Thalamus3.2
Thymus5.25
Thyroid4.3
Tongue3.1
Tonsil3.15
Trachea2.65
TrigeminalGanglion3.15
Uterus2.65
UterusCorpus2.85
WholeBlood3.6
Wholebrain2.75
colon3.25
pineal_day14.42
pineal_night8.46
retina4.35
small_intestine3.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P8848
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.64 ± 0.18
Basal Forebrain7.82 ± 0.2
Basal Part of Pons7.93 ± 0.13
Cerebellar Cortex7.74 ± 0.15
Cerebellar Nuclei8.06 ± 0.21
Claustrum7.51 ± 0.3
Epithalamus7.84 ± 0.22
Frontal Lobe7.84 ± 0.2
Globus Pallidus8.19 ± 0.18
Hypothalamus7.81 ± 0.16
Insula7.78 ± 0.11
Limbic Lobe7.78 ± 0.22
Mesencephalon7.93 ± 0.23
Myelencephalon7.87 ± 0.22
Occipital Lobe8.07 ± 0.22
Parietal Lobe7.91 ± 0.19
Pontine Tegmentum7.84 ± 0.23
Striatum8.17 ± 0.17
Subthalamus8.1 ± 0.14
Temporal Lobe7.76 ± 0.2
Thalamus7.96 ± 0.22
White Matter8.19 ± 0.09
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D14Ertd231eCBCerebellum0.37
0.9
D14Ertd231eCTXCerebral cortex0.27
0.42
D14Ertd231eHIPHippocampal region1.39
2.26
D14Ertd231eHPFHippocampal formation1.2
1.79
D14Ertd231eHYHypothalamus1.03
2.18
D14Ertd231eLSXLateral septal complex0
0
D14Ertd231eMBMidbrain0.36
0.69
D14Ertd231eMYMedulla1.79
3.07
D14Ertd231eOLFOlfactory bulb0.74
1.27
D14Ertd231ePPons3.05
5.82
D14Ertd231ePALPallidum0.16
0.44
D14Ertd231eRHPRetrohippocampal region0.4
0.33
D14Ertd231esAMYStriatum-like amygdalar nuclei0.2
0.17
D14Ertd231eSTRStriatum0.46
0.56
D14Ertd231eSTRdStriatum dorsal region0.17
0.25
D14Ertd231eSTRvStriatum ventral region1.98
2.15
D14Ertd231eTHThalamus0.38
0.28
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00080493 21 579 599 VLKPLLSGSIPVEQFVQTLEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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