AutismKB 2.0

Annotation Detail for EXOC2


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Basic Information Top
Gene Symbol:EXOC2 ( FLJ11026,SEC5,SEC5L1,Sec5p )
Gene Full Name: exocyst complex component 2
Band: 6p25.3
Quick LinksEntrez ID:55770; OMIM: NA; Uniprot ID:EXOC2_HUMAN; ENSEMBL ID: ENSG00000112685; HGNC ID: 24968
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst9 / 62319144
fetus29 / 56401251
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor15 / 26384556
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia6 / 9725061
normal130 / 336030738
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone3 / 7165541
bone marrow0 / 488010 
brain48 / 110098943
cervix0 / 481710 
connective tissue13 / 14925587
ear2 / 16212123
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine11 / 23447246
kidney7 / 21177733
larynx0 / 241450 
liver4 / 20774319
lung4 / 33697411
lymph0 / 442700 
lymph node5 / 9161054
mammary gland8 / 15327152
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas5 / 21481223
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta11 / 28082539
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen3 / 5395255
stomach2 / 9661920
testis26 / 33044278
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219349_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.8
Adipocyte6.55
AdrenalCortex7.8
Adrenalgland5.75
Amygdala6.85
Appendix7.3
AtrioventricularNode5.6
BDCA4+_DentriticCells26.45
Bonemarrow6.3
BronchialEpithelialCells7.25
CD105+_Endothelial6.8
CD14+_Monocytes7.2
CD19+_BCells(neg._sel.)12.7
CD33+_Myeloid8.8
CD34+9.45
CD4+_Tcells10.45
CD56+_NKCells38.1
CD71+_EarlyErythroid6.4
CD8+_Tcells20.4
CardiacMyocytes9.6
Caudatenucleus6.1
Cerebellum5.55
CerebellumPeduncles7.75
CiliaryGanglion5.15
CingulateCortex7.2
Colorectaladenocarcinoma6.95
DorsalRootGanglion5.15
FetalThyroid6.85
Fetalbrain6.65
Fetalliver5.65
Fetallung5.05
GlobusPallidus5
Heart8.7
Hypothalamus7.55
Kidney5.65
Leukemia_chronicMyelogenousK-5626.2
Leukemia_promyelocytic-HL-606
Leukemialymphoblastic(MOLT-4)5.35
Liver9.2
Lung7.05
Lymphnode5.5
Lymphoma_burkitts(Daudi)8.75
Lymphoma_burkitts(Raji)9.5
MedullaOblongata6.05
OccipitalLobe5.7
OlfactoryBulb5.25
Ovary4.55
Pancreas5.45
PancreaticIslet7.2
ParietalLobe7.35
Pituitary8.15
Placenta7
Pons6.65
PrefrontalCortex8.4
Prostate7.15
Salivarygland5.55
SkeletalMuscle8.95
Skin5.35
SmoothMuscle7.5
Spinalcord7.3
SubthalamicNucleus6.4
SuperiorCervicalGanglion8.9
TemporalLobe7.4
Testis5.95
TestisGermCell7.2
TestisIntersitial6.45
TestisLeydigCell7.1
TestisSeminiferousTubule5.95
Thalamus6.95
Thymus5.35
Thyroid8.3
Tongue7.15
Tonsil6.75
Trachea5.6
TrigeminalGanglion7.95
Uterus5.45
UterusCorpus6.4
WholeBlood7.4
Wholebrain5.35
colon6.5
pineal_day8.52
pineal_night10.44
retina8.7
small_intestine6.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8978_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.57 ± 0.33
Basal Forebrain6.88 ± 0.2
Basal Part of Pons6.86 ± 0.21
Cerebellar Cortex6.5 ± 0.24
Cerebellar Nuclei7.15 ± 0.18
Claustrum6.66 ± 0.52
Epithalamus6.5 ± 0.49
Frontal Lobe6.65 ± 0.34
Globus Pallidus7.14 ± 0.23
Hypothalamus6.78 ± 0.45
Insula6.72 ± 0.19
Limbic Lobe6.7 ± 0.35
Mesencephalon6.85 ± 0.36
Myelencephalon6.72 ± 0.35
Occipital Lobe6.89 ± 0.23
Parietal Lobe6.79 ± 0.34
Pontine Tegmentum6.83 ± 0.36
Striatum6.77 ± 0.3
Subthalamus6.93 ± 0.15
Temporal Lobe6.77 ± 0.31
Thalamus6.86 ± 0.23
White Matter7.73 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Exoc2CBCerebellum11.53
14.54
Exoc2CTXCerebral cortex11.46
9.31
Exoc2HIPHippocampal region6.34
7.56
Exoc2HPFHippocampal formation5.47
5.96
Exoc2HYHypothalamus1.13
0.89
Exoc2LSXLateral septal complex0.75
0.64
Exoc2MBMidbrain5.07
4.76
Exoc2MYMedulla11.14
12.14
Exoc2OLFOlfactory bulb12.16
10.11
Exoc2PPons10.27
11.23
Exoc2PALPallidum5.34
4.45
Exoc2RHPRetrohippocampal region3.05
2.34
Exoc2sAMYStriatum-like amygdalar nuclei7.77
5.58
Exoc2STRStriatum5.17
3.83
Exoc2STRdStriatum dorsal region4.85
3.74
Exoc2STRvStriatum ventral region7.23
4.79
Exoc2THThalamus3.85
3.55
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00069078 17 634 650 GVLECKPGEASVFQQPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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