AutismKB 2.0

Annotation Detail for HR


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Basic Information Top
Gene Symbol:HR ( ALUNC,AU,FLJ98880,HSA277165,MUHH,MUHH1 )
Gene Full Name: hairless homolog (mouse)
Band: 8p21.3
Quick LinksEntrez ID:55806; OMIM: 602302; Uniprot ID:HAIR_HUMAN; ENSEMBL ID: ENSG00000168453; HGNC ID: 5172
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult15 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal80 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor8 / 12494964
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain59 / 110098953
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye9 / 21105442
heart1 / 8962611
intestine3 / 23447212
kidney1 / 2117774
larynx2 / 2414582
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin13 / 21057461
spleen0 / 539520 
stomach3 / 9661931
testis6 / 33044218
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210086_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.6
Adipocyte6.7
AdrenalCortex7.1
Adrenalgland5.75
Amygdala7.2
Appendix7.2
AtrioventricularNode7
BDCA4+_DentriticCells5.85
Bonemarrow7.95
BronchialEpithelialCells5.7
CD105+_Endothelial6.9
CD14+_Monocytes5.85
CD19+_BCells(neg._sel.)6.55
CD33+_Myeloid8.4
CD34+6.75
CD4+_Tcells6
CD56+_NKCells6.95
CD71+_EarlyErythroid6.3
CD8+_Tcells5.2
CardiacMyocytes7.85
Caudatenucleus6.5
Cerebellum6.95
CerebellumPeduncles8.55
CiliaryGanglion5.75
CingulateCortex9.7
Colorectaladenocarcinoma7.65
DorsalRootGanglion5.3
FetalThyroid6.3
Fetalbrain7.25
Fetalliver5.9
Fetallung5.35
GlobusPallidus5.05
Heart8
Hypothalamus8.5
Kidney6.75
Leukemia_chronicMyelogenousK-5625.7
Leukemia_promyelocytic-HL-606
Leukemialymphoblastic(MOLT-4)6.45
Liver8.65
Lung6.9
Lymphnode5.9
Lymphoma_burkitts(Daudi)8.5
Lymphoma_burkitts(Raji)9.35
MedullaOblongata8.15
OccipitalLobe6.75
OlfactoryBulb6.5
Ovary4.45
Pancreas5.35
PancreaticIslet7
ParietalLobe8.05
Pituitary9.75
Placenta5.95
Pons6.3
PrefrontalCortex14.35
Prostate7.35
Salivarygland5.45
SkeletalMuscle10.65
Skin5.65
SmoothMuscle6.6
Spinalcord7.35
SubthalamicNucleus8.4
SuperiorCervicalGanglion14.5
TemporalLobe6.45
Testis6.1
TestisGermCell6.5
TestisIntersitial5.7
TestisLeydigCell6.85
TestisSeminiferousTubule5.6
Thalamus9.6
Thymus4.3
Thyroid8.6
Tongue7.65
Tonsil6.3
Trachea5.75
TrigeminalGanglion7.05
Uterus4.65
UterusCorpus9.8
WholeBlood6.65
Wholebrain5.95
colon6.45
pineal_day35.76
pineal_night29.98
retina8.575
small_intestine6.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11636_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.46 ± 0.99
Basal Forebrain3.14 ± 0.59
Basal Part of Pons3.7 ± 0.48
Cerebellar Cortex3.89 ± 0.49
Cerebellar Nuclei3.53 ± 0.6
Claustrum4.26 ± 0.81
Epithalamus2.74 ± 0.5
Frontal Lobe3.48 ± 0.58
Globus Pallidus3.85 ± 0.73
Hypothalamus3.03 ± 0.45
Insula3.11 ± 0.93
Limbic Lobe3.53 ± 0.76
Mesencephalon3.47 ± 0.71
Myelencephalon3.66 ± 0.67
Occipital Lobe4.11 ± 0.73
Parietal Lobe3.84 ± 0.53
Pontine Tegmentum3.56 ± 0.75
Striatum3.02 ± 0.9
Subthalamus3.58 ± 0.62
Temporal Lobe3.38 ± 0.71
Thalamus3.84 ± 0.6
White Matter4.15 ± 0.84
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
HrCBCerebellum45.08
49.5
HrCTXCerebral cortex84.44
64.01
HrHIPHippocampal region26.41
25.5
HrHPFHippocampal formation33.91
29.36
HrHYHypothalamus25.11
17.15
HrLSXLateral septal complex8.93
5.79
HrMBMidbrain30.99
24.12
HrMYMedulla39
41.22
HrOLFOlfactory bulb50.48
39.7
HrPPons30.83
32.17
HrPALPallidum26.38
21.59
HrRHPRetrohippocampal region51
38.01
HrsAMYStriatum-like amygdalar nuclei15.89
11
HrSTRStriatum22.51
15.67
HrSTRdStriatum dorsal region23.36
16.43
HrSTRvStriatum ventral region27.22
18.05
HrTHThalamus72.32
58.77
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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