AutismKB 2.0

Annotation Detail for UTP6


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Basic Information Top
Gene Symbol:UTP6 ( C17orf40,HCA66 )
Gene Full Name: UTP6, small subunit (SSU) processome component, homolog (yeast)
Band: 17q11.2
Quick LinksEntrez ID:55813; OMIM: NA; Uniprot ID:UTP6_HUMAN; ENSEMBL ID: ENSG00000108651; HGNC ID: 18279
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus17 / 56401230
neonate3 / 3109796
infant0 / 236200 
juvenile2 / 5555635
adult101 / 193912152
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218715_at
Cell line Expression level Expression bar
721_B_lymphoblasts163.95
Adipocyte20.75
AdrenalCortex23.75
Adrenalgland18
Amygdala24.5
Appendix22.35
AtrioventricularNode16.95
BDCA4+_DentriticCells131.3
Bonemarrow21.5
BronchialEpithelialCells95.55
CD105+_Endothelial44
CD14+_Monocytes75.1
CD19+_BCells(neg._sel.)126.25
CD33+_Myeloid56.65
CD34+96.3
CD4+_Tcells94.25
CD56+_NKCells54.25
CD71+_EarlyErythroid22.9
CD8+_Tcells97
CardiacMyocytes40.05
Caudatenucleus19.05
Cerebellum17.1
CerebellumPeduncles23.5
CiliaryGanglion12.9
CingulateCortex22.15
Colorectaladenocarcinoma48.15
DorsalRootGanglion15.55
FetalThyroid32.85
Fetalbrain62.45
Fetalliver18.3
Fetallung40.3
GlobusPallidus14.2
Heart27.15
Hypothalamus26.4
Kidney17.75
Leukemia_chronicMyelogenousK-562140.55
Leukemia_promyelocytic-HL-60126
Leukemialymphoblastic(MOLT-4)74.5
Liver28
Lung22.9
Lymphnode59.2
Lymphoma_burkitts(Daudi)168.4
Lymphoma_burkitts(Raji)49.7
MedullaOblongata22.4
OccipitalLobe18.8
OlfactoryBulb32.85
Ovary16.85
Pancreas26.05
PancreaticIslet42.4
ParietalLobe22.6
Pituitary32.45
Placenta27.3
Pons26.25
PrefrontalCortex39.7
Prostate29.7
Salivarygland17.4
SkeletalMuscle39.25
Skin17.65
SmoothMuscle53.75
Spinalcord24.15
SubthalamicNucleus20.15
SuperiorCervicalGanglion26.1
TemporalLobe27.5
Testis31.6
TestisGermCell46.8
TestisIntersitial29.35
TestisLeydigCell37
TestisSeminiferousTubule46.75
Thalamus21.6
Thymus26.1
Thyroid29.85
Tongue21.85
Tonsil43.2
Trachea17.65
TrigeminalGanglion23.1
Uterus20.3
UterusCorpus20.15
WholeBlood39.15
Wholebrain16.8
colon20.8
pineal_day36.2
pineal_night37.88
retina24.85
small_intestine20.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_844_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.11 ± 0.46
Basal Forebrain6.1 ± 0.1
Basal Part of Pons5.67 ± 0.57
Cerebellar Cortex6.27 ± 0.24
Cerebellar Nuclei5.51 ± 0.45
Claustrum5.58 ± 0.44
Epithalamus5.92 ± 0.38
Frontal Lobe5.83 ± 0.44
Globus Pallidus5.71 ± 0.38
Hypothalamus5.89 ± 0.54
Insula5.98 ± 0.33
Limbic Lobe6 ± 0.44
Mesencephalon5.92 ± 0.41
Myelencephalon5.88 ± 0.44
Occipital Lobe5.96 ± 0.33
Parietal Lobe5.83 ± 0.38
Pontine Tegmentum5.81 ± 0.45
Striatum5.8 ± 0.33
Subthalamus5.85 ± 0.36
Temporal Lobe6.02 ± 0.43
Thalamus5.73 ± 0.44
White Matter6.77 ± 0.55
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Utp6CBCerebellum26.55
40.39
Utp6CTXCerebral cortex53.13
39.62
Utp6HIPHippocampal region37.13
49.15
Utp6HPFHippocampal formation42.68
47.1
Utp6HYHypothalamus33.64
25.86
Utp6LSXLateral septal complex21.8
14.18
Utp6MBMidbrain31.18
29.61
Utp6MYMedulla55.48
68.85
Utp6OLFOlfactory bulb52.05
41.73
Utp6PPons40.54
45.08
Utp6PALPallidum37.74
35.59
Utp6RHPRetrohippocampal region56.06
45.47
Utp6sAMYStriatum-like amygdalar nuclei38.94
29.65
Utp6STRStriatum38.21
27.37
Utp6STRdStriatum dorsal region37.81
26.69
Utp6STRvStriatum ventral region45.04
32.22
Utp6THThalamus44.91
38.79
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064091 16 203 218 ASMDVENPDYSEEILK Peptide Atlas
UTP6_HUMAN_2 7 2 8 AEIIQER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018