AutismKB 2.0

Annotation Detail for DOK5


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Basic Information Top
Gene Symbol:DOK5 ( C20orf180,MGC16926 )
Gene Full Name: docking protein 5
Band: 20q13.2
Quick LinksEntrez ID:55816; OMIM: 608334; Uniprot ID:DOK5_HUMAN; ENSEMBL ID: ENSG00000101134; HGNC ID: 16173
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus65 / 564012115
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma10 / 10688393
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal109 / 336030732
ovarian tumor22 / 76682286
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain90 / 110098981
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine2 / 2344728
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary23 / 102051225
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214844_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.8
Adipocyte6.85
AdrenalCortex7.25
Adrenalgland5.85
Amygdala64
Appendix7.35
AtrioventricularNode5.4
BDCA4+_DentriticCells6.85
Bonemarrow7.05
BronchialEpithelialCells6.3
CD105+_Endothelial6.9
CD14+_Monocytes7
CD19+_BCells(neg._sel.)7.5
CD33+_Myeloid8.3
CD34+8.1
CD4+_Tcells7.15
CD56+_NKCells8.1
CD71+_EarlyErythroid6.35
CD8+_Tcells6.65
CardiacMyocytes8.45
Caudatenucleus6.25
Cerebellum8.1
CerebellumPeduncles7.8
CiliaryGanglion5
CingulateCortex7.05
Colorectaladenocarcinoma6.15
DorsalRootGanglion8.45
FetalThyroid6.7
Fetalbrain502.6
Fetalliver6.1
Fetallung5.4
GlobusPallidus5.15
Heart9.1
Hypothalamus22.9
Kidney5.8
Leukemia_chronicMyelogenousK-5626.2
Leukemia_promyelocytic-HL-606.1
Leukemialymphoblastic(MOLT-4)5.35
Liver9.3
Lung7.45
Lymphnode5.9
Lymphoma_burkitts(Daudi)8.8
Lymphoma_burkitts(Raji)10.1
MedullaOblongata9.35
OccipitalLobe10
OlfactoryBulb5.45
Ovary5.05
Pancreas5.6
PancreaticIslet7.4
ParietalLobe7.2
Pituitary8.15
Placenta7.05
Pons6.85
PrefrontalCortex20.85
Prostate7.85
Salivarygland5.55
SkeletalMuscle8.1
Skin5.75
SmoothMuscle9
Spinalcord9.65
SubthalamicNucleus9.35
SuperiorCervicalGanglion20.85
TemporalLobe7.65
Testis6
TestisGermCell5.25
TestisIntersitial5.45
TestisLeydigCell6.8
TestisSeminiferousTubule5.95
Thalamus11.55
Thymus5.4
Thyroid8.85
Tongue6.65
Tonsil6.05
Trachea5.85
TrigeminalGanglion10.5
Uterus5.75
UterusCorpus6.1
WholeBlood7.45
Wholebrain73.55
colon7
pineal_day11.88
pineal_night12.52
retina34.55
small_intestine6.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6766_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.69 ± 0.82
Basal Forebrain3.14 ± 0.36
Basal Part of Pons2.77 ± 0.36
Cerebellar Cortex2.73 ± 0.49
Cerebellar Nuclei3.49 ± 0.77
Claustrum3.6 ± 0.86
Epithalamus3.34 ± 0.67
Frontal Lobe3.46 ± 0.7
Globus Pallidus3.19 ± 0.71
Hypothalamus3.34 ± 0.68
Insula3.7 ± 0.38
Limbic Lobe3.23 ± 0.64
Mesencephalon3.29 ± 0.67
Myelencephalon3.3 ± 0.65
Occipital Lobe2.78 ± 0.66
Parietal Lobe3.16 ± 0.66
Pontine Tegmentum3.36 ± 0.67
Striatum3.37 ± 0.64
Subthalamus3.75 ± 0.21
Temporal Lobe3.22 ± 0.72
Thalamus3.13 ± 0.65
White Matter2.74 ± 0.18
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018