AutismKB 2.0

Annotation Detail for KDM3A


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Basic Information Top
Gene Symbol:KDM3A ( DKFZp686A24246,DKFZp686P07111,JHDM2A,JHMD2A,JMJD1,JMJD1A,KIAA0742,TSGA )
Gene Full Name: lysine (K)-specific demethylase 3A
Band: 2p11.2
Quick LinksEntrez ID:55818; OMIM: 611512; Uniprot ID:KDM3A_HUMAN; ENSEMBL ID: ENSG00000115548; HGNC ID: 20815
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus35 / 56401262
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult117 / 193912160
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma10 / 82823120
colorectal tumor7 / 11424661
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor9 / 26384534
glioma7 / 10688365
head and neck tumor13 / 13630295
kidney tumor5 / 6895972
leukemia4 / 9584241
liver tumor4 / 9635941
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia8 / 9725082
normal179 / 336030753
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder4 / 29757134
blood5 / 12347840
bone7 / 7165597
bone marrow0 / 488010 
brain57 / 110098951
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus1 / 2020949
eye21 / 21105499
heart10 / 89626111
intestine13 / 23447255
kidney11 / 21177751
larynx6 / 24145248
liver8 / 20774338
lung15 / 33697444
lymph0 / 442700 
lymph node10 / 91610109
mammary gland6 / 15327139
mouth8 / 67052119
muscle9 / 10771583
nerve0 / 157680 
ovary5 / 10205148
pancreas3 / 21481213
parathyroid5 / 20539243
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate7 / 18934536
salivary gland0 / 201550 
skin7 / 21057433
spleen1 / 5395218
stomach5 / 9661951
testis62 / 330442187
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea11 / 52413209
umbilical cord0 / 136800 
uterus16 / 23287868
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212689_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts405.95
Adipocyte14.35
AdrenalCortex34.7
Adrenalgland13.45
Amygdala70.65
Appendix31.45
AtrioventricularNode20.95
BDCA4+_DentriticCells459.9
Bonemarrow8.5
BronchialEpithelialCells28.8
CD105+_Endothelial157.15
CD14+_Monocytes40
CD19+_BCells(neg._sel.)243.25
CD33+_Myeloid154.2
CD34+306.1
CD4+_Tcells538.4
CD56+_NKCells566.45
CD71+_EarlyErythroid80.75
CD8+_Tcells572.7
CardiacMyocytes34.7
Caudatenucleus44.9
Cerebellum11.85
CerebellumPeduncles22.55
CiliaryGanglion14.45
CingulateCortex42.85
Colorectaladenocarcinoma39.85
DorsalRootGanglion16.5
FetalThyroid28.05
Fetalbrain27.65
Fetalliver23.6
Fetallung131
GlobusPallidus19.3
Heart13
Hypothalamus100.3
Kidney13.15
Leukemia_chronicMyelogenousK-56277.8
Leukemia_promyelocytic-HL-6055.35
Leukemialymphoblastic(MOLT-4)161.05
Liver12.3
Lung22.15
Lymphnode97.7
Lymphoma_burkitts(Daudi)51.35
Lymphoma_burkitts(Raji)109.4
MedullaOblongata42.3
OccipitalLobe43.4
OlfactoryBulb67.55
Ovary48.35
Pancreas169.25
PancreaticIslet78.45
ParietalLobe40.35
Pituitary50.7
Placenta33.25
Pons29.2
PrefrontalCortex109.65
Prostate60.6
Salivarygland38.7
SkeletalMuscle18.15
Skin63.55
SmoothMuscle66.7
Spinalcord72.5
SubthalamicNucleus23.1
SuperiorCervicalGanglion35.25
TemporalLobe20.65
Testis115.55
TestisGermCell361.7
TestisIntersitial479.05
TestisLeydigCell225
TestisSeminiferousTubule317.6
Thalamus29.95
Thymus31.25
Thyroid84.4
Tongue30.7
Tonsil55.35
Trachea25.65
TrigeminalGanglion23.05
Uterus98.9
UterusCorpus30.95
WholeBlood361.3
Wholebrain44.25
colon37.95
pineal_day72.02
pineal_night71.54
retina64.775
small_intestine24.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P258037
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.45 ± 0.55
Basal Forebrain4.91 ± 0.25
Basal Part of Pons4.83 ± 0.29
Cerebellar Cortex4.31 ± 0.31
Cerebellar Nuclei4.48 ± 0.71
Claustrum4.15 ± 1.08
Epithalamus5.41 ± 0.48
Frontal Lobe4.79 ± 0.43
Globus Pallidus5.19 ± 0.25
Hypothalamus4.8 ± 0.53
Insula4.59 ± 0.46
Limbic Lobe4.29 ± 0.55
Mesencephalon4.73 ± 0.54
Myelencephalon4.64 ± 0.5
Occipital Lobe4.39 ± 0.55
Parietal Lobe4.72 ± 0.54
Pontine Tegmentum4.74 ± 0.52
Striatum5.1 ± 0.35
Subthalamus4.52 ± 0.67
Temporal Lobe4.68 ± 0.42
Thalamus4.71 ± 0.46
White Matter4.43 ± 0.48
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00078036 18 712 729 SQIHEPENLMPTQIIPGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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