AutismKB 2.0

Annotation Detail for PAG1


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Basic Information Top
Gene Symbol:PAG1 ( CBP,FLJ37858,MGC138364,PAG )
Gene Full Name: phosphoprotein associated with glycosphingolipid microdomains 1
Band: 8q21.13
Quick LinksEntrez ID:55824; OMIM: 605767; Uniprot ID:PAG1_HUMAN; ENSEMBL ID: ENSG00000076641; HGNC ID: 30043
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia9 / 9584293
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia11 / 97250113
normal132 / 336030739
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood11 / 12347889
bone0 / 716550 
bone marrow5 / 48801102
brain40 / 110098936
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye10 / 21105447
heart1 / 8962611
intestine6 / 23447225
kidney5 / 21177723
larynx0 / 241450 
liver4 / 20774319
lung10 / 33697429
lymph1 / 4427022
lymph node22 / 91610240
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta11 / 28082539
prostate5 / 18934526
salivary gland0 / 201550 
skin14 / 21057466
spleen4 / 5395274
stomach0 / 966190 
testis0 / 3304420 
thymus9 / 81131110
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P61684
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.52 ± 0.54
Basal Forebrain6.92 ± 0.28
Basal Part of Pons7.14 ± 0.5
Cerebellar Cortex7.49 ± 0.37
Cerebellar Nuclei7.33 ± 0.3
Claustrum5.79 ± 0.71
Epithalamus6.42 ± 0.59
Frontal Lobe6.94 ± 0.45
Globus Pallidus6.51 ± 0.33
Hypothalamus6.91 ± 0.27
Insula6.89 ± 0.28
Limbic Lobe6.48 ± 0.41
Mesencephalon6.67 ± 0.54
Myelencephalon6.84 ± 0.56
Occipital Lobe6.89 ± 0.38
Parietal Lobe6.98 ± 0.49
Pontine Tegmentum6.78 ± 0.52
Striatum6.58 ± 0.41
Subthalamus7 ± 0.44
Temporal Lobe6.72 ± 0.47
Thalamus7.23 ± 0.45
White Matter6.5 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pag1CBCerebellum19.45
25.35
Pag1CTXCerebral cortex15.28
11.19
Pag1HIPHippocampal region11.55
11.08
Pag1HPFHippocampal formation12.39
10.85
Pag1HYHypothalamus8.84
6.23
Pag1LSXLateral septal complex24.95
19.46
Pag1MBMidbrain5.55
4.92
Pag1MYMedulla17.33
17.91
Pag1OLFOlfactory bulb31.47
28.96
Pag1PPons11.37
10.08
Pag1PALPallidum9.1
7.01
Pag1RHPRetrohippocampal region14.48
11.09
Pag1sAMYStriatum-like amygdalar nuclei10.21
7.93
Pag1STRStriatum11.6
8.58
Pag1STRdStriatum dorsal region8.54
6.38
Pag1STRvStriatum ventral region15.81
10.59
Pag1THThalamus12.95
9.97
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000289 11 222 232 AEFAEYASVDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018