AutismKB 2.0

Annotation Detail for TMEM111


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Basic Information Top
Gene Symbol:TMEM111 ( POB )
Gene Full Name: transmembrane protein 111
Band: 3p25.3
Quick LinksEntrez ID:55831; OMIM: NA; Uniprot ID:TM111_HUMAN; ENSEMBL ID: ENSG00000125037; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus38 / 56401267
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult160 / 193912182
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma12 / 82823144
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor8 / 26384530
glioma3 / 10688328
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor8 / 9635983
lung tumor6 / 10312758
lymphoma3 / 7175541
non-neoplasia4 / 9725041
normal240 / 336030771
ovarian tumor15 / 76682195
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer15 / 102680146
retinoblastoma3 / 4635664
skin tumor9 / 12494972
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland7 / 33197210
ascites3 / 4001574
bladder1 / 2975733
blood21 / 123478170
bone5 / 7165569
bone marrow6 / 48801122
brain48 / 110098943
cervix1 / 4817120
connective tissue12 / 14925580
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye16 / 21105475
heart0 / 896260 
intestine18 / 23447276
kidney13 / 21177761
larynx1 / 2414541
liver17 / 20774381
lung34 / 336974100
lymph1 / 4427022
lymph node3 / 9161032
mammary gland11 / 15327171
mouth1 / 6705214
muscle10 / 10771592
nerve0 / 157680 
ovary15 / 102051146
pancreas18 / 21481283
parathyroid4 / 20539194
pharynx9 / 41328217
pituitary gland2 / 16585120
placenta6 / 28082521
prostate20 / 189345105
salivary gland0 / 201550 
skin24 / 210574113
spleen0 / 539520 
stomach5 / 9661951
testis27 / 33044281
thymus1 / 8113112
thyroid2 / 4747342
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus16 / 23287868
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217882_at
Cell line Expression level Expression bar
721_B_lymphoblasts123.05
Adipocyte251.4
AdrenalCortex48.2
Adrenalgland110.3
Amygdala67.85
Appendix56.9
AtrioventricularNode21.4
BDCA4+_DentriticCells229
Bonemarrow207.1
BronchialEpithelialCells310.3
CD105+_Endothelial133.6
CD14+_Monocytes388.55
CD19+_BCells(neg._sel.)141.2
CD33+_Myeloid178.7
CD34+110.15
CD4+_Tcells76.25
CD56+_NKCells158.6
CD71+_EarlyErythroid1281.05
CD8+_Tcells81
CardiacMyocytes110.2
Caudatenucleus84.6
Cerebellum26.85
CerebellumPeduncles34.85
CiliaryGanglion27.35
CingulateCortex88.9
Colorectaladenocarcinoma35.25
DorsalRootGanglion28.9
FetalThyroid164.95
Fetalbrain31.2
Fetalliver125.85
Fetallung82.3
GlobusPallidus23
Heart36.75
Hypothalamus207
Kidney50.55
Leukemia_chronicMyelogenousK-562166
Leukemia_promyelocytic-HL-6035.9
Leukemialymphoblastic(MOLT-4)38.35
Liver63.75
Lung68.3
Lymphnode39.5
Lymphoma_burkitts(Daudi)31.65
Lymphoma_burkitts(Raji)12.55
MedullaOblongata54.35
OccipitalLobe74.5
OlfactoryBulb60.25
Ovary27.95
Pancreas24.4
PancreaticIslet77.95
ParietalLobe67.45
Pituitary104.45
Placenta64.5
Pons50.55
PrefrontalCortex72.75
Prostate47.7
Salivarygland41.05
SkeletalMuscle44.85
Skin30.7
SmoothMuscle170.7
Spinalcord111.6
SubthalamicNucleus44.35
SuperiorCervicalGanglion11.3
TemporalLobe48.35
Testis444.05
TestisGermCell288.35
TestisIntersitial447.75
TestisLeydigCell200.7
TestisSeminiferousTubule228.5
Thalamus134.9
Thymus59.65
Thyroid96.4
Tongue33.75
Tonsil62.3
Trachea50.2
TrigeminalGanglion20.85
Uterus34.6
UterusCorpus51
WholeBlood369.2
Wholebrain154.7
colon84.1
pineal_day207.52
pineal_night219.74
retina98.125
small_intestine118.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P69226
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.52 ± 0.33
Basal Forebrain6.07 ± 0.32
Basal Part of Pons6.77 ± 0.18
Cerebellar Cortex6.45 ± 0.35
Cerebellar Nuclei6.51 ± 0.38
Claustrum5.92 ± 0.49
Epithalamus6.2 ± 0.16
Frontal Lobe6.74 ± 0.34
Globus Pallidus6.35 ± 0.34
Hypothalamus6.56 ± 0.25
Insula6.61 ± 0.33
Limbic Lobe6.5 ± 0.36
Mesencephalon6.38 ± 0.54
Myelencephalon6.44 ± 0.43
Occipital Lobe6.01 ± 0.37
Parietal Lobe6.48 ± 0.35
Pontine Tegmentum6.42 ± 0.41
Striatum6.14 ± 0.29
Subthalamus6.43 ± 0.61
Temporal Lobe6.61 ± 0.31
Thalamus6.43 ± 0.28
White Matter6.24 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem111CBCerebellum6.47
13.11
Tmem111CTXCerebral cortex23.61
22.41
Tmem111HIPHippocampal region31.38
48.14
Tmem111HPFHippocampal formation30.81
41.89
Tmem111HYHypothalamus29.7
28.09
Tmem111LSXLateral septal complex8.41
7.72
Tmem111MBMidbrain5.51
8.76
Tmem111MYMedulla3.06
5.87
Tmem111OLFOlfactory bulb22.07
23.51
Tmem111PPons9.69
18.16
Tmem111PALPallidum10.84
12.69
Tmem111RHPRetrohippocampal region29.29
31.81
Tmem111sAMYStriatum-like amygdalar nuclei13.43
12.96
Tmem111STRStriatum13.64
12.37
Tmem111STRdStriatum dorsal region14.53
13.51
Tmem111STRvStriatum ventral region15.38
11.95
Tmem111THThalamus18.36
23.98
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00042791 25 220 244 TEWEALELTDHQWALDDVEEELMAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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