AutismKB 2.0

Annotation Detail for CENPJ


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Basic Information Top
Gene Symbol:CENPJ ( BM032,CPAP,LAP,LIP1,MCPH6,MGC131581,MGC131582,MGC142222,MGC142224,SASS4,Sas-4 )
Gene Full Name: centromere protein J
Band: 13q12.12-q12.13
Quick LinksEntrez ID:55835; OMIM: 609279; Uniprot ID:CENPJ_HUMAN; ENSEMBL ID: ENSG00000151849; HGNC ID: 17272
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor7 / 11936958
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal67 / 336030719
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow4 / 4880181
brain10 / 11009899
cervix1 / 4817120
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue8 / 21572237
esophagus1 / 2020949
eye2 / 2110549
heart0 / 896260 
intestine5 / 23447221
kidney2 / 2117779
larynx0 / 241450 
liver6 / 20774328
lung3 / 3369748
lymph0 / 442700 
lymph node5 / 9161054
mammary gland4 / 15327126
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach5 / 9661951
testis14 / 33044242
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220885_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.75
Adipocyte7.2
AdrenalCortex11.05
Adrenalgland7.7
Amygdala7.5
Appendix7.7
AtrioventricularNode9.35
BDCA4+_DentriticCells7.3
Bonemarrow7.6
BronchialEpithelialCells6.8
CD105+_Endothelial6.45
CD14+_Monocytes6.75
CD19+_BCells(neg._sel.)6.85
CD33+_Myeloid8.45
CD34+8.4
CD4+_Tcells6.9
CD56+_NKCells7.4
CD71+_EarlyErythroid6.6
CD8+_Tcells6.15
CardiacMyocytes9.8
Caudatenucleus6.6
Cerebellum6.4
CerebellumPeduncles8.85
CiliaryGanglion6.2
CingulateCortex7.75
Colorectaladenocarcinoma6.4
DorsalRootGanglion6
FetalThyroid7.05
Fetalbrain7.1
Fetalliver6.6
Fetallung5.65
GlobusPallidus7.25
Heart10.9
Hypothalamus7.55
Kidney7.1
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-606.45
Leukemialymphoblastic(MOLT-4)9.4
Liver15.5
Lung7.7
Lymphnode5.85
Lymphoma_burkitts(Daudi)9.6
Lymphoma_burkitts(Raji)9.3
MedullaOblongata6.7
OccipitalLobe6.3
OlfactoryBulb5.5
Ovary5.85
Pancreas6
PancreaticIslet11.05
ParietalLobe8.7
Pituitary13.35
Placenta7.3
Pons7.25
PrefrontalCortex8.55
Prostate7.45
Salivarygland8.4
SkeletalMuscle12.5
Skin7
SmoothMuscle8
Spinalcord7.75
SubthalamicNucleus7.9
SuperiorCervicalGanglion10.6
TemporalLobe6.65
Testis8.5
TestisGermCell6.6
TestisIntersitial7.3
TestisLeydigCell7.75
TestisSeminiferousTubule6.35
Thalamus10
Thymus5.25
Thyroid8.35
Tongue10.4
Tonsil7.1
Trachea5.95
TrigeminalGanglion10.75
Uterus5.45
UterusCorpus11.65
WholeBlood7.65
Wholebrain5.5
colon7
pineal_day8.56
pineal_night8.14
retina8.325
small_intestine6.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_154_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.35 ± 0.57
Basal Forebrain5.03 ± 0.27
Basal Part of Pons5.29 ± 0.34
Cerebellar Cortex5.48 ± 0.26
Cerebellar Nuclei5.53 ± 0.5
Claustrum5.92 ± 0.45
Epithalamus4.37 ± 0.6
Frontal Lobe4.68 ± 0.5
Globus Pallidus4.88 ± 0.59
Hypothalamus4.77 ± 0.38
Insula4.82 ± 0.52
Limbic Lobe4.79 ± 0.58
Mesencephalon5.16 ± 0.59
Myelencephalon4.98 ± 0.58
Occipital Lobe5.59 ± 0.63
Parietal Lobe5.06 ± 0.48
Pontine Tegmentum4.82 ± 0.54
Striatum4.54 ± 0.53
Subthalamus5.1 ± 0.21
Temporal Lobe4.94 ± 0.53
Thalamus5.28 ± 0.43
White Matter5.02 ± 0.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CenpjCBCerebellum22.89
31.59
CenpjCTXCerebral cortex12.45
8.96
CenpjHIPHippocampal region10.43
9.87
CenpjHPFHippocampal formation15.34
13.48
CenpjHYHypothalamus1.83
1.52
CenpjLSXLateral septal complex0.7
0.64
CenpjMBMidbrain4.95
4.73
CenpjMYMedulla12.44
13.17
CenpjOLFOlfactory bulb16.7
13.51
CenpjPPons13.36
13.62
CenpjPALPallidum4.97
4.29
CenpjRHPRetrohippocampal region23.82
18.54
CenpjsAMYStriatum-like amygdalar nuclei14.17
10.56
CenpjSTRStriatum7.4
5.96
CenpjSTRdStriatum dorsal region7.28
6.32
CenpjSTRvStriatum ventral region7.1
4.74
CenpjTHThalamus5.57
4.27
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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