AutismKB 2.0

Annotation Detail for CENPN


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Basic Information Top
Gene Symbol:CENPN ( BM039,C16orf60,CENP-N,FLJ13607,FLJ22660 )
Gene Full Name: centromere protein N
Band: 16q23.2
Quick LinksEntrez ID:55839; OMIM: 611509; Uniprot ID:CENPN_HUMAN; ENSEMBL ID: ENSG00000166451; HGNC ID: 30873
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus13 / 56401223
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor4 / 34366116
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor21 / 136302154
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal79 / 336030723
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer24 / 102680233
retinoblastoma3 / 4635664
skin tumor4 / 12494932
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites9 / 40015224
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow4 / 4880181
brain28 / 110098925
cervix4 / 4817183
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye5 / 21105423
heart3 / 8962633
intestine8 / 23447234
kidney7 / 21177733
larynx0 / 241450 
liver5 / 20774324
lung6 / 33697417
lymph0 / 442700 
lymph node10 / 91610109
mammary gland6 / 15327139
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx20 / 41328483
pituitary gland0 / 165850 
placenta7 / 28082524
prostate25 / 189345132
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219555_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts124.65
Adipocyte11.2
AdrenalCortex11.1
Adrenalgland8.45
Amygdala9.1
Appendix11.2
AtrioventricularNode8.3
BDCA4+_DentriticCells9.3
Bonemarrow10.2
BronchialEpithelialCells36.2
CD105+_Endothelial138
CD14+_Monocytes9.5
CD19+_BCells(neg._sel.)9.25
CD33+_Myeloid10.7
CD34+16.85
CD4+_Tcells9.4
CD56+_NKCells10.25
CD71+_EarlyErythroid105.7
CD8+_Tcells8.35
CardiacMyocytes19.8
Caudatenucleus8.3
Cerebellum7.65
CerebellumPeduncles11.05
CiliaryGanglion6.95
CingulateCortex9.85
Colorectaladenocarcinoma21.25
DorsalRootGanglion7.9
FetalThyroid9.45
Fetalbrain8.8
Fetalliver32.45
Fetallung8.75
GlobusPallidus6.9
Heart13.5
Hypothalamus9.7
Kidney9.5
Leukemia_chronicMyelogenousK-562162.9
Leukemia_promyelocytic-HL-6014.7
Leukemialymphoblastic(MOLT-4)91.8
Liver15.05
Lung10.1
Lymphnode7.45
Lymphoma_burkitts(Daudi)58.9
Lymphoma_burkitts(Raji)15.3
MedullaOblongata8.25
OccipitalLobe7.85
OlfactoryBulb7.15
Ovary6.9
Pancreas7.85
PancreaticIslet11.85
ParietalLobe10.7
Pituitary10.45
Placenta9
Pons9.15
PrefrontalCortex11
Prostate72.8
Salivarygland7.75
SkeletalMuscle14.5
Skin7.7
SmoothMuscle14.55
Spinalcord9.9
SubthalamicNucleus8.95
SuperiorCervicalGanglion12.4
TemporalLobe10.65
Testis8.85
TestisGermCell11.1
TestisIntersitial11.55
TestisLeydigCell11.75
TestisSeminiferousTubule8.6
Thalamus9.75
Thymus9.6
Thyroid11.25
Tongue9.45
Tonsil10.15
Trachea7.55
TrigeminalGanglion10.95
Uterus7.4
UterusCorpus12.2
WholeBlood9.95
Wholebrain7.35
colon9.6
pineal_day10.76
pineal_night10.9
retina10.85
small_intestine8.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P88740
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.59 ± 0.58
Basal Forebrain4.71 ± 0.53
Basal Part of Pons5.04 ± 0.15
Cerebellar Cortex4.4 ± 0.31
Cerebellar Nuclei5.62 ± 0.26
Claustrum4.78 ± 0.8
Epithalamus4.13 ± 0.7
Frontal Lobe5.01 ± 0.43
Globus Pallidus5.86 ± 0.22
Hypothalamus4.82 ± 0.49
Insula4.53 ± 0.33
Limbic Lobe4.52 ± 0.49
Mesencephalon4.91 ± 0.63
Myelencephalon4.85 ± 0.54
Occipital Lobe4.48 ± 0.53
Parietal Lobe4.93 ± 0.55
Pontine Tegmentum4.95 ± 0.55
Striatum5.23 ± 0.33
Subthalamus5.49 ± 0.49
Temporal Lobe4.79 ± 0.47
Thalamus5.01 ± 0.46
White Matter6.34 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2610510J17RikCBCerebellum0
0
2610510J17RikCTXCerebral cortex0
0
2610510J17RikHIPHippocampal region0
0
2610510J17RikHPFHippocampal formation0
0
2610510J17RikHYHypothalamus0
0
2610510J17RikLSXLateral septal complex0
0
2610510J17RikMBMidbrain0
0
2610510J17RikMYMedulla0
0
2610510J17RikOLFOlfactory bulb0
0
2610510J17RikPPons0
0
2610510J17RikPALPallidum0
0
2610510J17RikRHPRetrohippocampal region0
0
2610510J17RiksAMYStriatum-like amygdalar nuclei0
0
2610510J17RikSTRStriatum0
0
2610510J17RikSTRdStriatum dorsal region0
0
2610510J17RikSTRvStriatum ventral region0
0
2610510J17RikTHThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CENPN_HUMAN_1 11 1 11 MDETVAEFIKR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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