AutismKB 2.0

Annotation Detail for WWC3


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Basic Information Top
Gene Symbol:WWC3 ( BM042,KIAA1280 )
Gene Full Name: WWC family member 3
Band: Xp22.2
Quick LinksEntrez ID:55841; OMIM: NA; Uniprot ID:WWC3_HUMAN; ENSEMBL ID: ENSG00000047644; HGNC ID: 29237
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst5 / 6231980
fetus41 / 56401272
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor4 / 34366116
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor15 / 26384556
glioma5 / 10688346
head and neck tumor5 / 13630236
kidney tumor3 / 6895943
leukemia3 / 9584231
liver tumor7 / 9635972
lung tumor11 / 103127106
lymphoma8 / 71755111
non-neoplasia1 / 9725010
normal163 / 336030748
ovarian tumor3 / 7668239
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone3 / 7165541
bone marrow0 / 488010 
brain27 / 110098924
cervix4 / 4817183
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus0 / 202090 
eye3 / 21105414
heart7 / 8962678
intestine10 / 23447242
kidney15 / 21177770
larynx1 / 2414541
liver7 / 20774333
lung28 / 33697483
lymph5 / 44270112
lymph node17 / 91610185
mammary gland3 / 15327119
mouth4 / 6705259
muscle0 / 1077150 
nerve1 / 1576863
ovary3 / 10205129
pancreas7 / 21481232
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta20 / 28082571
prostate11 / 18934558
salivary gland0 / 201550 
skin8 / 21057437
spleen4 / 5395274
stomach1 / 9661910
testis4 / 33044212
thymus5 / 8113161
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219520_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts27.85
Adipocyte7.4
AdrenalCortex10.2
Adrenalgland9.75
Amygdala8.35
Appendix8.35
AtrioventricularNode6.15
BDCA4+_DentriticCells10.55
Bonemarrow7.95
BronchialEpithelialCells7.6
CD105+_Endothelial16.1
CD14+_Monocytes12.75
CD19+_BCells(neg._sel.)191.7
CD33+_Myeloid32.9
CD34+21.05
CD4+_Tcells41
CD56+_NKCells28.3
CD71+_EarlyErythroid25.85
CD8+_Tcells32.8
CardiacMyocytes12.15
Caudatenucleus6.8
Cerebellum6.3
CerebellumPeduncles8.8
CiliaryGanglion5.6
CingulateCortex7.95
Colorectaladenocarcinoma11.35
DorsalRootGanglion6.1
FetalThyroid12.6
Fetalbrain8.25
Fetalliver6.65
Fetallung20.55
GlobusPallidus5.55
Heart24.6
Hypothalamus11.7
Kidney6.6
Leukemia_chronicMyelogenousK-5626.3
Leukemia_promyelocytic-HL-606.95
Leukemialymphoblastic(MOLT-4)6.45
Liver11
Lung30.8
Lymphnode10.9
Lymphoma_burkitts(Daudi)9.9
Lymphoma_burkitts(Raji)11.95
MedullaOblongata6.65
OccipitalLobe7.1
OlfactoryBulb18.5
Ovary5.2
Pancreas6.55
PancreaticIslet10.35
ParietalLobe8.7
Pituitary8.85
Placenta96.25
Pons7.35
PrefrontalCortex11.2
Prostate10.9
Salivarygland6.6
SkeletalMuscle9.5
Skin6.1
SmoothMuscle18.7
Spinalcord13.75
SubthalamicNucleus6.9
SuperiorCervicalGanglion9.15
TemporalLobe6.9
Testis7.7
TestisGermCell16.3
TestisIntersitial6.65
TestisLeydigCell7.7
TestisSeminiferousTubule6.75
Thalamus8.55
Thymus6.75
Thyroid12.95
Tongue7.85
Tonsil9.25
Trachea6.6
TrigeminalGanglion13.6
Uterus13.35
UterusCorpus7.8
WholeBlood54.7
Wholebrain6.6
colon7.95
pineal_day9.1
pineal_night9.34
retina47.275
small_intestine12.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P345650
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.15 ± 0.22
Basal Forebrain9.5 ± 0.29
Basal Part of Pons8.85 ± 0.18
Cerebellar Cortex9.56 ± 0.18
Cerebellar Nuclei9.64 ± 0.27
Claustrum9.06 ± 0.16
Epithalamus9.56 ± 0.51
Frontal Lobe9.16 ± 0.33
Globus Pallidus10.2 ± 0.36
Hypothalamus8.99 ± 0.42
Insula9.09 ± 0.2
Limbic Lobe9.19 ± 0.37
Mesencephalon9.47 ± 0.44
Myelencephalon9.39 ± 0.41
Occipital Lobe9.76 ± 0.5
Parietal Lobe9.27 ± 0.32
Pontine Tegmentum9.4 ± 0.33
Striatum9.5 ± 0.51
Subthalamus9.33 ± 0.17
Temporal Lobe9.2 ± 0.26
Thalamus9.57 ± 0.31
White Matter10.58 ± 0.2
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00537148 7 306 312 RLEEELR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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