AutismKB 2.0

Annotation Detail for ARHGAP15


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Basic Information Top
Gene Symbol:ARHGAP15 ( BM046 )
Gene Full Name: Rho GTPase activating protein 15
Band: 2q22.2-q22.3
Quick LinksEntrez ID:55843; OMIM: 610578; Uniprot ID:RHG15_HUMAN; ENSEMBL ID: ENSG00000075884; HGNC ID: 21030
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus43 / 56401276
neonate0 / 310970 
infant0 / 236200 
juvenile9 / 55556161
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia15 / 95842156
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma13 / 71755181
non-neoplasia4 / 9725041
normal119 / 336030735
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor18 / 125191143
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood22 / 123478178
bone0 / 716550 
bone marrow8 / 48801163
brain16 / 110098914
cervix0 / 481710 
connective tissue19 / 149255127
ear5 / 16212308
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart2 / 8962622
intestine3 / 23447212
kidney3 / 21177714
larynx0 / 241450 
liver3 / 20774314
lung9 / 33697426
lymph2 / 4427045
lymph node11 / 91610120
mammary gland3 / 15327119
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta4 / 28082514
prostate5 / 18934526
salivary gland0 / 201550 
skin1 / 2105744
spleen4 / 5395274
stomach0 / 966190 
testis2 / 3304426
thymus8 / 8113198
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218870_at
Cell line Expression level Expression bar
721_B_lymphoblasts226.95
Adipocyte3.7
AdrenalCortex3.9
Adrenalgland3.15
Amygdala3.85
Appendix3.75
AtrioventricularNode2.9
BDCA4+_DentriticCells175.15
Bonemarrow4.2
BronchialEpithelialCells3.65
CD105+_Endothelial17.9
CD14+_Monocytes101.75
CD19+_BCells(neg._sel.)540.3
CD33+_Myeloid52.9
CD34+291.4
CD4+_Tcells510.95
CD56+_NKCells300.55
CD71+_EarlyErythroid3.5
CD8+_Tcells462.55
CardiacMyocytes4.65
Caudatenucleus3.35
Cerebellum3
CerebellumPeduncles4.2
CiliaryGanglion2.7
CingulateCortex3.8
Colorectaladenocarcinoma3.7
DorsalRootGanglion6.8
FetalThyroid3.6
Fetalbrain3.7
Fetalliver3.4
Fetallung3.1
GlobusPallidus2.7
Heart4.7
Hypothalamus4.05
Kidney3
Leukemia_chronicMyelogenousK-5623.35
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)68.85
Liver4.9
Lung4.05
Lymphnode64.7
Lymphoma_burkitts(Daudi)74.95
Lymphoma_burkitts(Raji)6.2
MedullaOblongata3.4
OccipitalLobe3.35
OlfactoryBulb227.25
Ovary2.45
Pancreas3
PancreaticIslet3.95
ParietalLobe3.95
Pituitary4.3
Placenta3.8
Pons3.55
PrefrontalCortex4.6
Prostate4.3
Salivarygland3.8
SkeletalMuscle4.3
Skin2.85
SmoothMuscle4.2
Spinalcord4.65
SubthalamicNucleus3.4
SuperiorCervicalGanglion4.25
TemporalLobe3.4
Testis16.9
TestisGermCell13.4
TestisIntersitial17
TestisLeydigCell6.25
TestisSeminiferousTubule4.4
Thalamus3.8
Thymus18.45
Thyroid4.65
Tongue3.65
Tonsil36.65
Trachea3.1
TrigeminalGanglion3.75
Uterus3
UterusCorpus3.35
WholeBlood336.65
Wholebrain3.15
colon3.7
pineal_day4.62
pineal_night4.52
retina4.475
small_intestine3.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P255166
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.97 ± 0.58
Basal Forebrain3.34 ± 1.03
Basal Part of Pons4.41 ± 1.05
Cerebellar Cortex2.9 ± 0.53
Cerebellar Nuclei5.04 ± 0.55
Claustrum3.51 ± 0.64
Epithalamus5.12 ± 0.42
Frontal Lobe3.47 ± 0.86
Globus Pallidus5.85 ± 0.33
Hypothalamus3.85 ± 1.33
Insula3.45 ± 0.81
Limbic Lobe3.49 ± 0.88
Mesencephalon3.65 ± 0.94
Myelencephalon3.68 ± 0.85
Occipital Lobe3.37 ± 0.91
Parietal Lobe3.33 ± 1.11
Pontine Tegmentum3.34 ± 0.89
Striatum4.37 ± 0.62
Subthalamus3.88 ± 0.6
Temporal Lobe3.51 ± 0.79
Thalamus3.66 ± 0.69
White Matter6.11 ± 0.85
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Arhgap15CBCerebellum3.78
4.42
Arhgap15CTXCerebral cortex12.05
8.37
Arhgap15HIPHippocampal region5.7
5.58
Arhgap15HPFHippocampal formation4.3
3.95
Arhgap15HYHypothalamus0.28
0.24
Arhgap15LSXLateral septal complex0.03
0
Arhgap15MBMidbrain3.65
3.61
Arhgap15MYMedulla6.42
7.26
Arhgap15OLFOlfactory bulb7.07
5.72
Arhgap15PPons5.4
6.13
Arhgap15PALPallidum0.34
0.33
Arhgap15RHPRetrohippocampal region1.93
1.73
Arhgap15sAMYStriatum-like amygdalar nuclei0.73
1.15
Arhgap15STRStriatum0.53
0.49
Arhgap15STRdStriatum dorsal region0.56
0.47
Arhgap15STRvStriatum ventral region0.53
0.47
Arhgap15THThalamus1.11
0.94
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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