AutismKB 2.0

Annotation Detail for SLC22A11


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Basic Information Top
Gene Symbol:SLC22A11 ( MGC34282,OAT4,hOAT4 )
Gene Full Name: solute carrier family 22 (organic anion/urate transporter), member 11
Band: 11q13.1
Quick LinksEntrez ID:55867; OMIM: 607097; Uniprot ID:S22AB_HUMAN; ENSEMBL ID: ENSG00000168065; HGNC ID: 18120
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult109 / 193912156
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal134 / 336030739
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney15 / 21177770
larynx0 / 241450 
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta102 / 280825363
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220100_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.5
Adipocyte3.9
AdrenalCortex4.05
Adrenalgland3
Amygdala3.8
Appendix3.95
AtrioventricularNode3.05
BDCA4+_DentriticCells3.45
Bonemarrow3.8
BronchialEpithelialCells3.55
CD105+_Endothelial3.6
CD14+_Monocytes3.85
CD19+_BCells(neg._sel.)3.85
CD33+_Myeloid4.6
CD34+4.25
CD4+_Tcells3.9
CD56+_NKCells4.3
CD71+_EarlyErythroid3.4
CD8+_Tcells3.5
CardiacMyocytes4.55
Caudatenucleus3.25
Cerebellum4.05
CerebellumPeduncles4.05
CiliaryGanglion2.8
CingulateCortex3.9
Colorectaladenocarcinoma3.65
DorsalRootGanglion3.15
FetalThyroid3.5
Fetalbrain3.6
Fetalliver3.2
Fetallung3
GlobusPallidus2.7
Heart5.45
Hypothalamus3.9
Kidney38.4
Leukemia_chronicMyelogenousK-5623.2
Leukemia_promyelocytic-HL-603.2
Leukemialymphoblastic(MOLT-4)2.9
Liver7.3
Lung4.85
Lymphnode3.9
Lymphoma_burkitts(Daudi)4.6
Lymphoma_burkitts(Raji)5.4
MedullaOblongata3.25
OccipitalLobe3.2
OlfactoryBulb2.85
Ovary2.4
Pancreas2.9
PancreaticIslet4.15
ParietalLobe5.2
Pituitary4.65
Placenta34.3
Pons3.4
PrefrontalCortex4.5
Prostate4.2
Salivarygland3.3
SkeletalMuscle6.05
Skin6.05
SmoothMuscle4
Spinalcord3.9
SubthalamicNucleus3.3
SuperiorCervicalGanglion8.9
TemporalLobe3.3
Testis3.25
TestisGermCell3.1
TestisIntersitial3.15
TestisLeydigCell3.55
TestisSeminiferousTubule3.1
Thalamus3.6
Thymus2.8
Thyroid4.5
Tongue3.5
Tonsil4.1
Trachea3
TrigeminalGanglion3.65
Uterus2.95
UterusCorpus4.05
WholeBlood4.15
Wholebrain3.05
colon3.6
pineal_day4.38
pineal_night4.18
retina4.325
small_intestine3.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15520_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.27 ± 1
Basal Forebrain1.7 ± 0.26
Basal Part of Pons1.44 ± 0.47
Cerebellar Cortex1.7 ± 0.81
Cerebellar Nuclei2.13 ± 0.69
Claustrum2.77 ± 0.97
Epithalamus1.52 ± 0.8
Frontal Lobe1.62 ± 0.62
Globus Pallidus2.5 ± 0.41
Hypothalamus1.79 ± 0.61
Insula1.84 ± 0.93
Limbic Lobe1.86 ± 0.84
Mesencephalon1.96 ± 0.76
Myelencephalon1.88 ± 0.75
Occipital Lobe1.89 ± 0.69
Parietal Lobe1.97 ± 0.95
Pontine Tegmentum1.86 ± 0.73
Striatum2.02 ± 0.81
Subthalamus2.38 ± 0.02
Temporal Lobe1.71 ± 0.75
Thalamus1.81 ± 0.63
White Matter2.61 ± 0.59
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00424744 13 474 486 LGAMMGPLILMSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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