AutismKB 2.0

Annotation Detail for LMO3


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Basic Information Top
Gene Symbol:LMO3 ( DAT1,MGC26081,RBTN3,RBTNL2,RHOM3,Rhom-3 )
Gene Full Name: LIM domain only 3 (rhombotin-like 2)
Band: 12p12.3
Quick LinksEntrez ID:55885; OMIM: 180386; Uniprot ID:LMO3_HUMAN; ENSEMBL ID: ENSG00000048540; HGNC ID: 6643
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus148 / 564012262
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma8 / 10688374
head and neck tumor10 / 13630273
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia7 / 9725071
normal425 / 3360307126
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain437 / 1100989396
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine1 / 2344724
kidney5 / 21177723
larynx0 / 241450 
liver1 / 2077434
lung24 / 33697471
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle6 / 10771555
nerve1 / 1576863
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus3 / 8113136
thyroid11 / 47473231
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204424_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.5
Adipocyte79.55
AdrenalCortex11.85
Adrenalgland8
Amygdala595.75
Appendix46.6
AtrioventricularNode11.95
BDCA4+_DentriticCells5.4
Bonemarrow10.65
BronchialEpithelialCells7.5
CD105+_Endothelial6.35
CD14+_Monocytes5.35
CD19+_BCells(neg._sel.)5.25
CD33+_Myeloid6.75
CD34+6.1
CD4+_Tcells5.35
CD56+_NKCells5.85
CD71+_EarlyErythroid6.85
CD8+_Tcells5.25
CardiacMyocytes7.65
Caudatenucleus260.2
Cerebellum18.3
CerebellumPeduncles11.85
CiliaryGanglion5.4
CingulateCortex129.05
Colorectaladenocarcinoma5.85
DorsalRootGanglion8.55
FetalThyroid31.7
Fetalbrain476.45
Fetalliver6.7
Fetallung15.1
GlobusPallidus103
Heart8.55
Hypothalamus54.4
Kidney7.4
Leukemia_chronicMyelogenousK-5626.35
Leukemia_promyelocytic-HL-605.45
Leukemialymphoblastic(MOLT-4)6.3
Liver10.9
Lung16.35
Lymphnode6.25
Lymphoma_burkitts(Daudi)9
Lymphoma_burkitts(Raji)9.65
MedullaOblongata157.25
OccipitalLobe230.1
OlfactoryBulb18.6
Ovary4.95
Pancreas7.55
PancreaticIslet11.85
ParietalLobe145.8
Pituitary59.25
Placenta7.7
Pons107.85
PrefrontalCortex470.2
Prostate8.8
Salivarygland7.55
SkeletalMuscle12.95
Skin9.2
SmoothMuscle8.1
Spinalcord48.9
SubthalamicNucleus156.15
SuperiorCervicalGanglion22.85
TemporalLobe137.7
Testis6.3
TestisGermCell6.25
TestisIntersitial6.2
TestisLeydigCell9.25
TestisSeminiferousTubule6.85
Thalamus21.95
Thymus11.4
Thyroid118.9
Tongue7.35
Tonsil7.25
Trachea7.65
TrigeminalGanglion12.65
Uterus14.45
UterusCorpus31.35
WholeBlood7.55
Wholebrain148.75
colon13.25
pineal_day11.18
pineal_night8.72
retina35.1
small_intestine6.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9773_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.95 ± 0.49
Basal Forebrain9.03 ± 0.42
Basal Part of Pons9.92 ± 0.2
Cerebellar Cortex7.92 ± 0.43
Cerebellar Nuclei7.77 ± 0.71
Claustrum10.04 ± 0.25
Epithalamus8.74 ± 0.7
Frontal Lobe9.41 ± 0.52
Globus Pallidus8.19 ± 1.28
Hypothalamus8.69 ± 0.66
Insula9.58 ± 0.44
Limbic Lobe9.22 ± 0.76
Mesencephalon8.73 ± 1.01
Myelencephalon8.79 ± 0.8
Occipital Lobe7.84 ± 0.76
Parietal Lobe8.68 ± 0.59
Pontine Tegmentum8.7 ± 0.64
Striatum9.23 ± 0.84
Subthalamus8.42 ± 0.74
Temporal Lobe9.13 ± 0.57
Thalamus8.06 ± 0.53
White Matter6.55 ± 1.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lmo3CBCerebellum5.16
7.54
Lmo3CTXCerebral cortex43.37
42.06
Lmo3HIPHippocampal region92.81
100
Lmo3HPFHippocampal formation80.57
100
Lmo3HYHypothalamus10.27
10.93
Lmo3LSXLateral septal complex9.36
8.8
Lmo3MBMidbrain16.05
17.28
Lmo3MYMedulla4.47
5.15
Lmo3OLFOlfactory bulb90.26
100
Lmo3PPons6.92
9.28
Lmo3PALPallidum23.08
26.34
Lmo3RHPRetrohippocampal region63.47
81.7
Lmo3sAMYStriatum-like amygdalar nuclei53.63
56.45
Lmo3STRStriatum56.44
49.06
Lmo3STRdStriatum dorsal region68.82
59.1
Lmo3STRvStriatum ventral region33.35
26.5
Lmo3THThalamus4.5
6.71
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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