AutismKB 2.0

Annotation Detail for ZNF395


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZNF395 ( DKFZp434K1210,HDBP2,PBF,PRF-1,PRF1,Si-1-8-14 )
Gene Full Name: zinc finger protein 395
Band: 8p21.1
Quick LinksEntrez ID:55893; OMIM: 609494; Uniprot ID:ZN395_HUMAN; ENSEMBL ID: ENSG00000186918; HGNC ID: 18737
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus39 / 56401269
neonate5 / 31097160
infant0 / 236200 
juvenile1 / 5555617
adult120 / 193912161
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult0 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma4 / 8282348
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor13 / 26384549
glioma7 / 10688365
head and neck tumor11 / 13630280
kidney tumor13 / 68959188
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor12 / 103127116
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal225 / 336030766
ovarian tumor6 / 7668278
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor8 / 12494964
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor6 / 9025766
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal1 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow3 / 4880161
brain27 / 110098924
cervix3 / 4817162
connective tissue12 / 14925580
ear2 / 16212123
embryonic tissue14 / 21572264
esophagus1 / 2020949
eye31 / 211054146
heart4 / 8962644
intestine9 / 23447238
kidney20 / 21177794
larynx8 / 24145331
liver2 / 2077439
lung23 / 33697468
lymph0 / 442700 
lymph node23 / 91610251
mammary gland6 / 15327139
mouth1 / 6705214
muscle2 / 10771518
nerve2 / 15768126
ovary6 / 10205158
pancreas21 / 21481297
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta24 / 28082585
prostate8 / 18934542
salivary gland3 / 20155148
skin19 / 21057490
spleen8 / 53952148
stomach3 / 9661931
testis13 / 33044239
thymus5 / 8113161
thyroid5 / 47473105
tonsil7 / 16999411
trachea0 / 524130 
umbilical cord3 / 13680219
uterus16 / 23287868
vascular1 / 5178019
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218149_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts56.5
Adipocyte17.05
AdrenalCortex8.55
Adrenalgland10.65
Amygdala7
Appendix6.1
AtrioventricularNode4.35
BDCA4+_DentriticCells45.55
Bonemarrow5.75
BronchialEpithelialCells29.15
CD105+_Endothelial80.4
CD14+_Monocytes20.4
CD19+_BCells(neg._sel.)495.1
CD33+_Myeloid42.4
CD34+146.25
CD4+_Tcells37.4
CD56+_NKCells41.85
CD71+_EarlyErythroid6.55
CD8+_Tcells21.5
CardiacMyocytes13.85
Caudatenucleus5.1
Cerebellum4.5
CerebellumPeduncles6.45
CiliaryGanglion4.1
CingulateCortex5.5
Colorectaladenocarcinoma8.85
DorsalRootGanglion4.3
FetalThyroid34.65
Fetalbrain5.7
Fetalliver5
Fetallung22.4
GlobusPallidus4.2
Heart8.25
Hypothalamus6.3
Kidney5.25
Leukemia_chronicMyelogenousK-5624.85
Leukemia_promyelocytic-HL-605.75
Leukemialymphoblastic(MOLT-4)21.8
Liver7.65
Lung37.9
Lymphnode9.95
Lymphoma_burkitts(Daudi)36.65
Lymphoma_burkitts(Raji)7.9
MedullaOblongata5.1
OccipitalLobe5
OlfactoryBulb13.1
Ovary5.7
Pancreas12.05
PancreaticIslet94.3
ParietalLobe5.65
Pituitary6.7
Placenta43.35
Pons5.05
PrefrontalCortex16.95
Prostate54.25
Salivarygland15.15
SkeletalMuscle6.7
Skin8.55
SmoothMuscle11.35
Spinalcord7.65
SubthalamicNucleus4.95
SuperiorCervicalGanglion6.3
TemporalLobe5.75
Testis5.65
TestisGermCell16
TestisIntersitial4.45
TestisLeydigCell5.55
TestisSeminiferousTubule5.85
Thalamus5.7
Thymus24.6
Thyroid28.8
Tongue25.05
Tonsil18.7
Trachea15.85
TrigeminalGanglion5.8
Uterus20.6
UterusCorpus5.15
WholeBlood6.05
Wholebrain5.35
colon10.8
pineal_day8.94
pineal_night7.2
retina41.475
small_intestine19.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P153680
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.05 ± 0.48
Basal Forebrain4.77 ± 0.17
Basal Part of Pons4.58 ± 0.46
Cerebellar Cortex4.62 ± 0.47
Cerebellar Nuclei4.72 ± 0.37
Claustrum5.36 ± 0.64
Epithalamus4.52 ± 0.21
Frontal Lobe4.64 ± 0.47
Globus Pallidus5.27 ± 0.33
Hypothalamus4.4 ± 0.41
Insula4.7 ± 0.32
Limbic Lobe4.82 ± 0.61
Mesencephalon4.8 ± 0.6
Myelencephalon4.76 ± 0.53
Occipital Lobe4.89 ± 0.5
Parietal Lobe4.69 ± 0.56
Pontine Tegmentum4.65 ± 0.51
Striatum4.77 ± 0.41
Subthalamus4.37 ± 1.08
Temporal Lobe4.66 ± 0.56
Thalamus4.73 ± 0.42
White Matter5.22 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp395CBCerebellum3.14
3.24
Zfp395CTXCerebral cortex7.21
5.71
Zfp395HIPHippocampal region2.67
2.8
Zfp395HPFHippocampal formation5.99
5.44
Zfp395HYHypothalamus3.1
2.73
Zfp395LSXLateral septal complex0.23
0.33
Zfp395MBMidbrain4.58
5.17
Zfp395MYMedulla4.69
5.09
Zfp395OLFOlfactory bulb9.46
9.07
Zfp395PPons3.54
3.92
Zfp395PALPallidum0.53
0.47
Zfp395RHPRetrohippocampal region13.52
10.66
Zfp395sAMYStriatum-like amygdalar nuclei1.39
1.08
Zfp395STRStriatum2.21
1.69
Zfp395STRdStriatum dorsal region3.29
2.54
Zfp395STRvStriatum ventral region0.43
0.31
Zfp395THThalamus3.69
3.32
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved