AutismKB 2.0

Annotation Detail for THSD1


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Basic Information Top
Gene Symbol:THSD1 ( MGC74971,TMTSP,UNQ3010 )
Gene Full Name: thrombospondin, type I, domain containing 1
Band: 13q14.3
Quick LinksEntrez ID:55901; OMIM: NA; Uniprot ID:THSD1_HUMAN; ENSEMBL ID: ENSG00000136114; HGNC ID: 17754
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal72 / 336030721
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain20 / 110098918
cervix0 / 481710 
connective tissue1 / 1492556
ear2 / 16212123
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye9 / 21105442
heart4 / 8962644
intestine5 / 23447221
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle9 / 10771583
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta10 / 28082535
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219477_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.35
Adipocyte11.75
AdrenalCortex13.05
Adrenalgland10.3
Amygdala22.85
Appendix12.35
AtrioventricularNode9.45
BDCA4+_DentriticCells13.9
Bonemarrow12.05
BronchialEpithelialCells12.4
CD105+_Endothelial11.55
CD14+_Monocytes12.35
CD19+_BCells(neg._sel.)12.25
CD33+_Myeloid14.25
CD34+16.2
CD4+_Tcells12.65
CD56+_NKCells15.1
CD71+_EarlyErythroid11.45
CD8+_Tcells11.75
CardiacMyocytes15.8
Caudatenucleus11.05
Cerebellum9.9
CerebellumPeduncles13.85
CiliaryGanglion8.9
CingulateCortex12.6
Colorectaladenocarcinoma14.35
DorsalRootGanglion10.15
FetalThyroid12.4
Fetalbrain14.2
Fetalliver10.55
Fetallung15.75
GlobusPallidus8.9
Heart16.2
Hypothalamus24.35
Kidney9.8
Leukemia_chronicMyelogenousK-56210.95
Leukemia_promyelocytic-HL-609.15
Leukemialymphoblastic(MOLT-4)11.5
Liver16.05
Lung26.6
Lymphnode10.05
Lymphoma_burkitts(Daudi)15.6
Lymphoma_burkitts(Raji)17.4
MedullaOblongata11.4
OccipitalLobe11.15
OlfactoryBulb10.15
Ovary8.6
Pancreas22.25
PancreaticIslet12.55
ParietalLobe12.95
Pituitary14.35
Placenta13.95
Pons11.65
PrefrontalCortex20.55
Prostate14.5
Salivarygland9.8
SkeletalMuscle14.5
Skin9.55
SmoothMuscle13.25
Spinalcord13.2
SubthalamicNucleus11.6
SuperiorCervicalGanglion14.15
TemporalLobe11.5
Testis10.45
TestisGermCell10.2
TestisIntersitial10.3
TestisLeydigCell11.95
TestisSeminiferousTubule10.4
Thalamus12.45
Thymus9.65
Thyroid15.65
Tongue12
Tonsil12
Trachea10.3
TrigeminalGanglion12.6
Uterus11.95
UterusCorpus10.95
WholeBlood11.8
Wholebrain10.85
colon12.35
pineal_day16.02
pineal_night15.2
retina15
small_intestine12
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9753_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.21 ± 0.52
Basal Forebrain4.57 ± 0.5
Basal Part of Pons4.17 ± 0.41
Cerebellar Cortex5.16 ± 0.37
Cerebellar Nuclei4.43 ± 0.59
Claustrum4.69 ± 0.83
Epithalamus4.06 ± 0.55
Frontal Lobe4.29 ± 0.53
Globus Pallidus3.96 ± 0.51
Hypothalamus4.17 ± 0.61
Insula4.56 ± 0.38
Limbic Lobe4.74 ± 0.6
Mesencephalon4.48 ± 0.6
Myelencephalon4.5 ± 0.66
Occipital Lobe4.84 ± 0.6
Parietal Lobe4.67 ± 0.63
Pontine Tegmentum4.61 ± 0.7
Striatum4.57 ± 0.53
Subthalamus4.39 ± 0.78
Temporal Lobe4.51 ± 0.61
Thalamus4.33 ± 0.52
White Matter3.45 ± 1.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Thsd1CBCerebellum10.36
10.66
Thsd1CTXCerebral cortex15.69
11.37
Thsd1HIPHippocampal region9.51
9.29
Thsd1HPFHippocampal formation9.4
8.21
Thsd1HYHypothalamus28.59
27.04
Thsd1LSXLateral septal complex12.24
7.58
Thsd1MBMidbrain7.89
7.02
Thsd1MYMedulla6.39
6.62
Thsd1OLFOlfactory bulb33.62
29.79
Thsd1PPons7.35
7.66
Thsd1PALPallidum12.91
12.89
Thsd1RHPRetrohippocampal region8.96
6.39
Thsd1sAMYStriatum-like amygdalar nuclei3.44
2.75
Thsd1STRStriatum10.94
8.3
Thsd1STRdStriatum dorsal region8.42
6.37
Thsd1STRvStriatum ventral region24.69
18.64
Thsd1THThalamus16.01
13.41
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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