Annotation Detail for MLL5
Basic Information Top
| Gene Symbol: | MLL5 ( FLJ10078,FLJ14026,HDCMC04P,KMT2E,MGC70452 ) |
|---|---|
| Gene Full Name: | myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila) |
| Band: | 7q22.1 |
| Quick Links | Entrez ID:55904; OMIM: 608444; Uniprot ID:MLL5_HUMAN; ENSEMBL ID: ENSG00000005483; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.592262
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 7 / 70761 | 98 |  |
| blastocyst | 2 / 62319 | 32 |  |
| fetus | 44 / 564012 | 78 | |
| neonate | 1 / 31097 | 32 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 177 / 1939121 | 91 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 10 / 94178 | 106 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 16 / 114246 | 140 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 23 / 119369 | 192 | |
| germ cell tumor | 20 / 263845 | 75 | |
| glioma | 11 / 106883 | 102 | |
| head and neck tumor | 14 / 136302 | 102 | |
| kidney tumor | 7 / 68959 | 101 | |
| leukemia | 16 / 95842 | 166 | |
| liver tumor | 7 / 96359 | 72 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 252 / 3360307 | 74 | |
| ovarian tumor | 6 / 76682 | 78 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 3 / 125680 | 23 | |
| prostate cancer | 5 / 102680 | 48 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 8 / 90257 | 88 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 4 / 40015 | 99 | |
| bladder | 2 / 29757 | 67 | |
| blood | 11 / 123478 | 89 | |
| bone | 7 / 71655 | 97 | |
| bone marrow | 10 / 48801 | 204 |  |
| brain | 46 / 1100989 | 41 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 6 / 16212 | 370 | |
| embryonic tissue | 14 / 215722 | 64 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 19 / 211054 | 90 | |
| heart | 3 / 89626 | 33 | |
| intestine | 23 / 234472 | 98 | |
| kidney | 18 / 211777 | 84 | |
| larynx | 1 / 24145 | 41 | |
| liver | 15 / 207743 | 72 | |
| lung | 27 / 336974 | 80 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 7 / 91610 | 76 | |
| mammary gland | 31 / 153271 | 202 | |
| mouth | 10 / 67052 | 149 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 9 / 102051 | 88 | |
| pancreas | 25 / 214812 | 116 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 3 / 41328 | 72 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 14 / 189345 | 73 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 13 / 210574 | 61 | |
| spleen | 4 / 53952 | 74 | |
| stomach | 25 / 96619 | 258 | |
| testis | 15 / 330442 | 45 | |
| thymus | 7 / 81131 | 86 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 12 / 232878 | 51 | |
| vascular | 3 / 51780 | 57 | |
Microarray in - Probe name: A_24_P196704
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 10.78 ± 0.28 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 10.77 ± 0.19 | |
| Basal Part of Pons | 10.38 ± 0.15 | |
| Cerebellar Cortex | 10.9 ± 0.14 | |
| Cerebellar Nuclei | 10.51 ± 0.16 | |
| Claustrum | 10.96 ± 0.29 | |
| Epithalamus | 10.44 ± 0.28 | |
| Frontal Lobe | 10.47 ± 0.3 | |
| Globus Pallidus | 10.8 ± 0.19 | |
| Hypothalamus | 10.4 ± 0.42 | |
| Insula | 10.55 ± 0.22 | |
| Limbic Lobe | 10.53 ± 0.29 | |
| Mesencephalon | 10.65 ± 0.26 | |
| Myelencephalon | 10.56 ± 0.33 | |
| Occipital Lobe | 10.85 ± 0.25 | |
| Parietal Lobe | 10.66 ± 0.24 | |
| Pontine Tegmentum | 10.65 ± 0.31 | |
| Striatum | 10.55 ± 0.32 | |
| Subthalamus | 10.66 ± 0.23 | |
| Temporal Lobe | 10.53 ± 0.31 | |
| Thalamus | 10.63 ± 0.22 | |
| White Matter | 11.24 ± 0.34 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Mll5 | CB | Cerebellum | 55.71 | |
| 67.24 | | |||
| Mll5 | CTX | Cerebral cortex | 100 | |
| 98.16 | | |||
| Mll5 | HIP | Hippocampal region | 66.59 | |
| 97.03 | | |||
| Mll5 | HPF | Hippocampal formation | 80.28 | |
| 92.9 | | |||
| Mll5 | HY | Hypothalamus | 60.32 | |
| 46.39 | | |||
| Mll5 | LSX | Lateral septal complex | 66.91 | |
| 50.76 | | |||
| Mll5 | MB | Midbrain | 56.65 | |
| 48.42 | | |||
| Mll5 | MY | Medulla | 53.07 | |
| 49.38 | | |||
| Mll5 | OLF | Olfactory bulb | 88.69 | |
| 81.82 | | |||
| Mll5 | P | Pons | 45.4 | |
| 41.98 | | |||
| Mll5 | PAL | Pallidum | 46.17 | |
| 38.38 | | |||
| Mll5 | RHP | Retrohippocampal region | 100 | |
| 89.17 | | |||
| Mll5 | sAMY | Striatum-like amygdalar nuclei | 57.63 | |
| 41.97 | | |||
| Mll5 | STR | Striatum | 74.41 | |
| 56.41 | | |||
| Mll5 | STRd | Striatum dorsal region | 76.32 | |
| 58.49 | | |||
| Mll5 | STRv | Striatum ventral region | 78.61 | |
| 57.84 | | |||
| Mll5 | TH | Thalamus | 51.64 | |
| 41.77 | |