AutismKB 2.0

Annotation Detail for MYO5C


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Basic Information Top
Gene Symbol:MYO5C ( MGC74969 )
Gene Full Name: myosin VC
Band: 15q21.2
Quick LinksEntrez ID:55930; OMIM: 610022; Uniprot ID:MYO5C_HUMAN; ENSEMBL ID: ENSG00000128833; HGNC ID: 7604
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus12 / 56401221
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult52 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor2 / 17290115
gastrointestinal tumor11 / 11936992
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal63 / 336030718
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain5 / 11009894
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus2 / 2020998
eye4 / 21105418
heart0 / 896260 
intestine6 / 23447225
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate8 / 18934542
salivary gland1 / 2015549
skin0 / 2105740 
spleen1 / 5395218
stomach11 / 96619113
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218966_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.35
Adipocyte3.4
AdrenalCortex3.55
Adrenalgland2.9
Amygdala3.8
Appendix6.65
AtrioventricularNode2.6
BDCA4+_DentriticCells3.85
Bonemarrow3.4
BronchialEpithelialCells3.45
CD105+_Endothelial3.55
CD14+_Monocytes3.65
CD19+_BCells(neg._sel.)3.65
CD33+_Myeloid4.4
CD34+32.1
CD4+_Tcells3.7
CD56+_NKCells4.15
CD71+_EarlyErythroid3.2
CD8+_Tcells3.35
CardiacMyocytes4.3
Caudatenucleus4.25
Cerebellum3.5
CerebellumPeduncles4.45
CiliaryGanglion2.4
CingulateCortex3.55
Colorectaladenocarcinoma4.75
DorsalRootGanglion2.6
FetalThyroid25.3
Fetalbrain3.45
Fetalliver2.95
Fetallung13.7
GlobusPallidus2.5
Heart4.4
Hypothalamus4
Kidney2.75
Leukemia_chronicMyelogenousK-5623.15
Leukemia_promyelocytic-HL-603.05
Leukemialymphoblastic(MOLT-4)2.85
Liver4.55
Lung4.15
Lymphnode3.6
Lymphoma_burkitts(Daudi)4.45
Lymphoma_burkitts(Raji)4.8
MedullaOblongata3.85
OccipitalLobe4.15
OlfactoryBulb4.45
Ovary2.3
Pancreas16.25
PancreaticIslet14.15
ParietalLobe3.65
Pituitary9.4
Placenta3.6
Pons3.3
PrefrontalCortex5.15
Prostate42.95
Salivarygland62.3
SkeletalMuscle3.95
Skin3.3
SmoothMuscle3.9
Spinalcord11.95
SubthalamicNucleus3.15
SuperiorCervicalGanglion3.9
TemporalLobe3.2
Testis4.55
TestisGermCell8.05
TestisIntersitial4
TestisLeydigCell4.8
TestisSeminiferousTubule5.15
Thalamus3.5
Thymus2.85
Thyroid47.5
Tongue3.35
Tonsil3.4
Trachea31.1
TrigeminalGanglion3.4
Uterus4.05
UterusCorpus3.1
WholeBlood3.8
Wholebrain3.05
colon10.3
pineal_day4.7
pineal_night4.68
retina5.15
small_intestine3.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12129_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.61 ± 1.08
Basal Forebrain3.32 ± 0.38
Basal Part of Pons3.22 ± 0.64
Cerebellar Cortex4.21 ± 0.4
Cerebellar Nuclei3.4 ± 0.66
Claustrum3.73 ± 0.65
Epithalamus4.84 ± 0.83
Frontal Lobe3.07 ± 0.78
Globus Pallidus2.95 ± 1.01
Hypothalamus3.25 ± 0.81
Insula2.63 ± 0.93
Limbic Lobe3.34 ± 0.79
Mesencephalon3.42 ± 0.69
Myelencephalon3.42 ± 0.8
Occipital Lobe3.98 ± 0.74
Parietal Lobe3.32 ± 0.77
Pontine Tegmentum3.39 ± 0.72
Striatum3.52 ± 0.87
Subthalamus3.28 ± 0.78
Temporal Lobe3.33 ± 0.75
Thalamus3.06 ± 0.64
White Matter2.83 ± 0.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Myo5cCBCerebellum1.75
2.06
Myo5cCTXCerebral cortex3.66
2.2
Myo5cHIPHippocampal region1.1
1.02
Myo5cHPFHippocampal formation1.72
1.28
Myo5cHYHypothalamus0.5
0.35
Myo5cLSXLateral septal complex0.28
0.16
Myo5cMBMidbrain1.16
1.21
Myo5cMYMedulla1.91
2
Myo5cOLFOlfactory bulb2.53
1.6
Myo5cPPons1.97
1.99
Myo5cPALPallidum0.8
0.48
Myo5cRHPRetrohippocampal region2.88
1.75
Myo5csAMYStriatum-like amygdalar nuclei1.37
0.84
Myo5cSTRStriatum3.19
1.85
Myo5cSTRdStriatum dorsal region4.45
2.58
Myo5cSTRvStriatum ventral region2
1.18
Myo5cTHThalamus7.29
4.64
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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