AutismKB 2.0

Annotation Detail for SULF2


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Basic Information Top
Gene Symbol:SULF2 ( DKFZp313E091,FLJ44488,FLJ90554,HSULF-2,KIAA1247,MGC126411 )
Gene Full Name: sulfatase 2
Band: 20q13.12
Quick LinksEntrez ID:55959; OMIM: 610013; Uniprot ID:SULF2_HUMAN; ENSEMBL ID: ENSG00000196562; HGNC ID: 20392
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst7 / 62319112
fetus33 / 56401258
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult158 / 193912181
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor36 / 94178382
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor13 / 114246113
esophageal tumor2 / 17290115
gastrointestinal tumor10 / 11936983
germ cell tumor6 / 26384522
glioma10 / 10688393
head and neck tumor24 / 136302176
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal130 / 336030738
ovarian tumor8 / 76682104
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone1 / 7165513
bone marrow1 / 4880120
brain41 / 110098937
cervix0 / 481710 
connective tissue9 / 14925560
ear2 / 16212123
embryonic tissue25 / 215722115
esophagus2 / 2020998
eye17 / 21105480
heart9 / 89626100
intestine18 / 23447276
kidney2 / 2117779
larynx9 / 24145372
liver6 / 20774328
lung6 / 33697417
lymph0 / 442700 
lymph node1 / 9161010
mammary gland40 / 153271260
mouth8 / 67052119
muscle2 / 10771518
nerve1 / 1576863
ovary8 / 10205178
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland1 / 1658560
placenta13 / 28082546
prostate4 / 18934521
salivary gland3 / 20155148
skin3 / 21057414
spleen1 / 5395218
stomach11 / 96619113
testis15 / 33044245
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus21 / 23287890
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P154605
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.56 ± 0.48
Basal Forebrain9.62 ± 0.22
Basal Part of Pons10.59 ± 0.13
Cerebellar Cortex9.18 ± 0.31
Cerebellar Nuclei9.79 ± 0.37
Claustrum9.59 ± 0.66
Epithalamus9.67 ± 0.57
Frontal Lobe9.83 ± 0.4
Globus Pallidus10.41 ± 0.48
Hypothalamus9.28 ± 0.5
Insula10.07 ± 0.45
Limbic Lobe10.17 ± 0.48
Mesencephalon9.52 ± 0.44
Myelencephalon9.6 ± 0.65
Occipital Lobe8.84 ± 0.49
Parietal Lobe9.42 ± 0.49
Pontine Tegmentum9.33 ± 0.32
Striatum9.61 ± 0.52
Subthalamus10.2 ± 0.13
Temporal Lobe9.75 ± 0.54
Thalamus9.13 ± 0.38
White Matter9.24 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sulf2CBCerebellum9.44
14.95
Sulf2CTXCerebral cortex100
100
Sulf2HIPHippocampal region57.97
97.23
Sulf2HPFHippocampal formation69.82
100
Sulf2HYHypothalamus40.82
42.93
Sulf2LSXLateral septal complex80.76
100
Sulf2MBMidbrain25.4
31.18
Sulf2MYMedulla14.93
21.09
Sulf2OLFOlfactory bulb37.72
40.3
Sulf2PPons21.25
29.29
Sulf2PALPallidum52.59
61.64
Sulf2RHPRetrohippocampal region97.98
100
Sulf2sAMYStriatum-like amygdalar nuclei37.85
35.93
Sulf2STRStriatum37.85
39.8
Sulf2STRdStriatum dorsal region31.35
31.72
Sulf2STRvStriatum ventral region40.76
42.73
Sulf2THThalamus36.1
46.09
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00137770 13 548 560 VYHVGLGDAAQPR Peptide Atlas
SULF2_HUMAN_709 5 709 713 KLLKR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018