AutismKB 2.0

Annotation Detail for MAPK9


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MAPK9 ( JNK-55,JNK2,JNK2A,JNK2ALPHA,JNK2B,JNK2BETA,PRKM9,SAPK,p54a,p54aSAPK )
Gene Full Name: mitogen-activated protein kinase 9
Band: 5q35.3
Quick LinksEntrez ID:5601; OMIM: 602896; Uniprot ID:MK09_HUMAN; ENSEMBL ID: ENSG00000050748; HGNC ID: 6886
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus24 / 56401242
neonate2 / 3109764
infant6 / 23620254
juvenile5 / 5555689
adult111 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma8 / 8282396
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia5 / 9584252
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia7 / 9725071
normal180 / 336030753
ovarian tumor1 / 7668213
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood5 / 12347840
bone5 / 7165569
bone marrow2 / 4880140
brain55 / 110098949
cervix3 / 4817162
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye15 / 21105471
heart0 / 896260 
intestine15 / 23447263
kidney10 / 21177747
larynx1 / 2414541
liver7 / 20774333
lung22 / 33697465
lymph1 / 4427022
lymph node7 / 9161076
mammary gland9 / 15327158
mouth0 / 670520 
muscle4 / 10771537
nerve1 / 1576863
ovary2 / 10205119
pancreas8 / 21481237
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta20 / 28082571
prostate5 / 18934526
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach3 / 9661931
testis12 / 33044236
thymus1 / 8113112
thyroid2 / 4747342
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord2 / 13680146
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210570_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.1
Adipocyte4.15
AdrenalCortex4.25
Adrenalgland3.95
Amygdala4.45
Appendix4.05
AtrioventricularNode3.05
BDCA4+_DentriticCells4.35
Bonemarrow3.9
BronchialEpithelialCells3.9
CD105+_Endothelial4
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.2
CD33+_Myeloid4.85
CD34+4.95
CD4+_Tcells4.45
CD56+_NKCells4.7
CD71+_EarlyErythroid3.65
CD8+_Tcells3.95
CardiacMyocytes4.85
Caudatenucleus3.65
Cerebellum8.05
CerebellumPeduncles6.55
CiliaryGanglion2.85
CingulateCortex5.3
Colorectaladenocarcinoma4.5
DorsalRootGanglion3.1
FetalThyroid3.9
Fetalbrain4.05
Fetalliver3.5
Fetallung3.3
GlobusPallidus5.15
Heart5.1
Hypothalamus5.15
Kidney3.25
Leukemia_chronicMyelogenousK-5623.65
Leukemia_promyelocytic-HL-603.6
Leukemialymphoblastic(MOLT-4)3.25
Liver5.25
Lung4.3
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.55
Lymphoma_burkitts(Raji)5.45
MedullaOblongata5
OccipitalLobe6.25
OlfactoryBulb3.2
Ovary2.7
Pancreas3.2
PancreaticIslet4.3
ParietalLobe5.8
Pituitary4.75
Placenta4.2
Pons4.35
PrefrontalCortex5.6
Prostate4.75
Salivarygland3.2
SkeletalMuscle4.6
Skin3.15
SmoothMuscle4.6
Spinalcord4.3
SubthalamicNucleus4.2
SuperiorCervicalGanglion7.3
TemporalLobe3.8
Testis3.5
TestisGermCell3.5
TestisIntersitial3.4
TestisLeydigCell4
TestisSeminiferousTubule3.45
Thalamus5.25
Thymus3.1
Thyroid4.8
Tongue3.95
Tonsil3.95
Trachea3.9
TrigeminalGanglion4
Uterus3.35
UterusCorpus3.65
WholeBlood4.2
Wholebrain5.15
colon4.05
pineal_day4.84
pineal_night4.82
retina4.725
small_intestine3.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P167692
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.09 ± 0.16
Basal Forebrain9.72 ± 0.23
Basal Part of Pons10.27 ± 0.34
Cerebellar Cortex9.85 ± 0.34
Cerebellar Nuclei10.19 ± 0.28
Claustrum10.66 ± 0.21
Epithalamus9.16 ± 0.43
Frontal Lobe9.95 ± 0.38
Globus Pallidus9.22 ± 0.38
Hypothalamus9.86 ± 0.43
Insula9.88 ± 0.29
Limbic Lobe10.08 ± 0.34
Mesencephalon9.9 ± 0.43
Myelencephalon9.9 ± 0.39
Occipital Lobe10.03 ± 0.37
Parietal Lobe10.1 ± 0.38
Pontine Tegmentum9.97 ± 0.33
Striatum9.64 ± 0.35
Subthalamus10.18 ± 0.12
Temporal Lobe10.02 ± 0.3
Thalamus9.9 ± 0.32
White Matter8.99 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mapk9CBCerebellum22.89
38.23
Mapk9CTXCerebral cortex86.15
81.43
Mapk9HIPHippocampal region47.48
64.13
Mapk9HPFHippocampal formation54.45
63.87
Mapk9HYHypothalamus74.83
71.98
Mapk9LSXLateral septal complex32.04
27.98
Mapk9MBMidbrain52.22
60.2
Mapk9MYMedulla43.9
72.12
Mapk9OLFOlfactory bulb61.67
63.77
Mapk9PPons50.73
78.88
Mapk9PALPallidum58.46
67.48
Mapk9RHPRetrohippocampal region76.01
70.9
Mapk9sAMYStriatum-like amygdalar nuclei79.82
73.57
Mapk9STRStriatum38.05
33.58
Mapk9STRdStriatum dorsal region26.93
23.54
Mapk9STRvStriatum ventral region55.47
46.11
Mapk9THThalamus61.89
62.8
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved