Annotation Detail for PRKX
Basic Information Top
| Gene Symbol: | PRKX ( PKX1 ) |
|---|---|
| Gene Full Name: | protein kinase, X-linked |
| Band: | Xp22.33 |
| Quick Links | Entrez ID:5613; OMIM: 300083; Uniprot ID:PRKX_HUMAN; ENSEMBL ID: ENSG00000183943; HGNC ID: 9441 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.390788
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 4 / 70761 | 56 |  |
| blastocyst | 9 / 62319 | 144 | |
| fetus | 7 / 564012 | 12 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 53 / 1939121 | 27 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 5 / 94178 | 53 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 7 / 263845 | 26 | |
| glioma | 9 / 106883 | 84 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 4 / 95842 | 41 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 8 / 103127 | 77 | |
| lymphoma | 5 / 71755 | 69 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 77 / 3360307 | 22 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 6 / 90257 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 3 / 40015 | 74 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 |  |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 22 / 1100989 | 19 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 16 / 215722 | 74 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 7 / 211054 | 33 | |
| heart | 1 / 89626 | 11 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 0 / 24145 | 0 | |
| liver | 3 / 207743 | 14 | |
| lung | 16 / 336974 | 47 | |
| lymph | 5 / 44270 | 112 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 9 / 153271 | 58 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 7 / 107715 | 64 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 7 / 189345 | 36 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 2 / 96619 | 20 | |
| testis | 5 / 330442 | 15 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 13 / 232878 | 55 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204060_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 20.95 | |
| Adipocyte | 5.65 | |
| AdrenalCortex | 6.5 | |
| Adrenalgland | 5.05 | |
| Amygdala | 6.8 | |
| Appendix | 6.35 | |
| AtrioventricularNode | 4.75 | |
| BDCA4+_DentriticCells | 71.95 | |
| Bonemarrow | 6.1 | |
| BronchialEpithelialCells | 6.3 | |
| CD105+_Endothelial | 9.05 | |
| CD14+_Monocytes | 62.05 | |
| CD19+_BCells(neg._sel.) | 76.25 | |
| CD33+_Myeloid | 113.8 | |
| CD34+ | 51.25 | |
| CD4+_Tcells | 217.55 |  |
| CD56+_NKCells | 158.25 | |
| CD71+_EarlyErythroid | 6.3 | |
| CD8+_Tcells | 201.4 | |
| CardiacMyocytes | 7.85 | |
| Caudatenucleus | 5.15 | |
| Cerebellum | 4.75 | |
| CerebellumPeduncles | 7.05 | |
| CiliaryGanglion | 4.4 | |
| CingulateCortex | 6.15 | |
| Colorectaladenocarcinoma | 8.9 | |
| DorsalRootGanglion | 4.8 | |
| FetalThyroid | 18.7 | |
| Fetalbrain | 7.45 | |
| Fetalliver | 5.1 | |
| Fetallung | 5.25 | |
| GlobusPallidus | 4.45 | |
| Heart | 7.85 | |
| Hypothalamus | 7.75 | |
| Kidney | 4.95 | |
| Leukemia_chronicMyelogenousK-562 | 5.5 | |
| Leukemia_promyelocytic-HL-60 | 5.9 | |
| Leukemialymphoblastic(MOLT-4) | 12.4 | |
| Liver | 8.25 | |
| Lung | 6.95 | |
| Lymphnode | 15.1 | |
| Lymphoma_burkitts(Daudi) | 7.85 | |
| Lymphoma_burkitts(Raji) | 17.65 | |
| MedullaOblongata | 5.55 | |
| OccipitalLobe | 5.35 | |
| OlfactoryBulb | 30.5 | |
| Ovary | 4.1 | |
| Pancreas | 4.95 | |
| PancreaticIslet | 6.35 | |
| ParietalLobe | 6.25 | |
| Pituitary | 7.05 | |
| Placenta | 7.05 | |
| Pons | 5.75 | |
| PrefrontalCortex | 7.95 | |
| Prostate | 7.55 | |
| Salivarygland | 4.95 | |
| SkeletalMuscle | 7.1 | |
| Skin | 4.75 | |
| SmoothMuscle | 7.1 | |
| Spinalcord | 7.1 | |
| SubthalamicNucleus | 5.4 | |
| SuperiorCervicalGanglion | 7.45 | |
| TemporalLobe | 5.7 | |
| Testis | 5.45 | |
| TestisGermCell | 8.05 | |
| TestisIntersitial | 5.3 | |
| TestisLeydigCell | 6.25 | |
| TestisSeminiferousTubule | 5.5 | |
| Thalamus | 6.3 | |
| Thymus | 7.85 | |
| Thyroid | 140.95 | |
| Tongue | 6.4 | |
| Tonsil | 7.95 | |
| Trachea | 5.25 | |
| TrigeminalGanglion | 6.5 | |
| Uterus | 6 | |
| UterusCorpus | 5.55 | |
| WholeBlood | 18.15 | |
| Wholebrain | 5.35 | |
| colon | 6.4 | |
| pineal_day | 7.48 | |
| pineal_night | 7.92 | |
| retina | 8.925 | |
| small_intestine | 6.15 | |
- Probe name: A_23_P217339
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.64 ± 0.54 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.01 ± 0.4 | |
| Basal Part of Pons | 2.95 ± 0.33 | |
| Cerebellar Cortex | 3.33 ± 0.47 | |
| Cerebellar Nuclei | 3.66 ± 0.7 | |
| Claustrum | 3.19 ± 0.74 | |
| Epithalamus | 4.67 ± 0.83 | |
| Frontal Lobe | 3.61 ± 0.72 | |
| Globus Pallidus | 5.89 ± 0.53 | |
| Hypothalamus | 3.99 ± 0.75 | |
| Insula | 3.8 ± 0.66 | |
| Limbic Lobe | 3.37 ± 0.73 | |
| Mesencephalon | 4.07 ± 0.83 | |
| Myelencephalon | 3.83 ± 0.68 | |
| Occipital Lobe | 3.99 ± 0.67 | |
| Parietal Lobe | 3.84 ± 0.65 | |
| Pontine Tegmentum | 4.02 ± 0.66 | |
| Striatum | 3.45 ± 0.86 | |
| Subthalamus | 4.38 ± 0.32 | |
| Temporal Lobe | 3.68 ± 0.67 | |
| Thalamus | 3.97 ± 0.67 | |
| White Matter | 4.69 ± 0.43 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Prkx | CB | Cerebellum | 19.61 | |
| 25.16 | | |||
| Prkx | CTX | Cerebral cortex | 16.19 | |
| 11.99 | | |||
| Prkx | HIP | Hippocampal region | 15.44 | |
| 15.21 | | |||
| Prkx | HPF | Hippocampal formation | 16.12 | |
| 14.39 | | |||
| Prkx | HY | Hypothalamus | 4.64 | |
| 3.39 | | |||
| Prkx | LSX | Lateral septal complex | 5.38 | |
| 3.61 | | |||
| Prkx | MB | Midbrain | 6.55 | |
| 6.4 | | |||
| Prkx | MY | Medulla | 9.93 | |
| 10.25 | | |||
| Prkx | OLF | Olfactory bulb | 19.13 | |
| 16.34 | | |||
| Prkx | P | Pons | 9.11 | |
| 8.71 | | |||
| Prkx | PAL | Pallidum | 5.6 | |
| 4.78 | | |||
| Prkx | RHP | Retrohippocampal region | 17.38 | |
| 13.18 | | |||
| Prkx | sAMY | Striatum-like amygdalar nuclei | 8.86 | |
| 6.29 | | |||
| Prkx | STR | Striatum | 7.97 | |
| 5.84 | | |||
| Prkx | STRd | Striatum dorsal region | 7.87 | |
| 6.03 | | |||
| Prkx | STRv | Striatum ventral region | 9.13 | |
| 6.03 | | |||
| Prkx | TH | Thalamus | 3.95 | |
| 3.27 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PRKX_HUMAN_1 | 17 | 1 | 17 | MEAPGLAQAAAAESDSR | PRIDE |