AutismKB 2.0

Annotation Detail for NDNL2


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Basic Information Top
Gene Symbol:NDNL2 ( HCA4,MAGEG1,MAGEL3,NSE3,NSMCE3 )
Gene Full Name: necdin-like 2
Band: 15q13.1
Quick LinksEntrez ID:56160; OMIM: 608243; Uniprot ID:MAGG1_HUMAN; ENSEMBL ID: ENSG00000185115; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus9 / 56401215
neonate0 / 310970 
infant1 / 2362042
juvenile4 / 5555671
adult40 / 193912120
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P124973
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.83 ± 0.51
Basal Forebrain4.85 ± 0.22
Basal Part of Pons5.35 ± 0.22
Cerebellar Cortex5.03 ± 0.52
Cerebellar Nuclei5.31 ± 0.63
Claustrum4.72 ± 0.63
Epithalamus4.83 ± 0.69
Frontal Lobe5.11 ± 0.45
Globus Pallidus4.98 ± 0.57
Hypothalamus5.11 ± 0.64
Insula5.24 ± 0.37
Limbic Lobe5.28 ± 0.46
Mesencephalon4.94 ± 0.53
Myelencephalon5.01 ± 0.52
Occipital Lobe5.26 ± 0.42
Parietal Lobe5.08 ± 0.41
Pontine Tegmentum5.09 ± 0.44
Striatum4.87 ± 0.5
Subthalamus5.44 ± 0.59
Temporal Lobe5.02 ± 0.47
Thalamus5.06 ± 0.38
White Matter4.45 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ndnl2CBCerebellum6.5
7.7
Ndnl2CTXCerebral cortex25.77
20.36
Ndnl2HIPHippocampal region30
48.93
Ndnl2HPFHippocampal formation31.49
40.27
Ndnl2HYHypothalamus5.14
5.89
Ndnl2LSXLateral septal complex2.85
1.9
Ndnl2MBMidbrain6.34
6.61
Ndnl2MYMedulla20.29
24.44
Ndnl2OLFOlfactory bulb24.53
21.44
Ndnl2PPons7.73
9.18
Ndnl2PALPallidum10.94
11.39
Ndnl2RHPRetrohippocampal region34.96
29.87
Ndnl2sAMYStriatum-like amygdalar nuclei13.75
11.59
Ndnl2STRStriatum8.12
6.65
Ndnl2STRdStriatum dorsal region6.87
5.52
Ndnl2STRvStriatum ventral region11.93
9.72
Ndnl2THThalamus12.58
14.12
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018