AutismKB 2.0

Annotation Detail for NDNL2


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Basic Information Top
Gene Symbol:NDNL2 ( HCA4,MAGEG1,MAGEL3,NSE3,NSMCE3 )
Gene Full Name: necdin-like 2
Band: 15q13.1
Quick LinksEntrez ID:56160; OMIM: 608243; Uniprot ID:MAGG1_HUMAN; ENSEMBL ID: ENSG00000185115; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus9 / 56401215
neonate0 / 310970 
infant1 / 2362042
juvenile4 / 5555671
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia4 / 9725041
normal69 / 336030720
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone4 / 7165555
bone marrow0 / 488010 
brain16 / 110098914
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus1 / 2020949
eye8 / 21105437
heart0 / 896260 
intestine2 / 2344728
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary1 / 1020519
pancreas3 / 21481213
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta6 / 28082521
prostate4 / 18934521
salivary gland0 / 201550 
skin7 / 21057433
spleen2 / 5395237
stomach1 / 9661910
testis2 / 3304426
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P124973
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.83 ± 0.51
Basal Forebrain4.85 ± 0.22
Basal Part of Pons5.35 ± 0.22
Cerebellar Cortex5.03 ± 0.52
Cerebellar Nuclei5.31 ± 0.63
Claustrum4.72 ± 0.63
Epithalamus4.83 ± 0.69
Frontal Lobe5.11 ± 0.45
Globus Pallidus4.98 ± 0.57
Hypothalamus5.11 ± 0.64
Insula5.24 ± 0.37
Limbic Lobe5.28 ± 0.46
Mesencephalon4.94 ± 0.53
Myelencephalon5.01 ± 0.52
Occipital Lobe5.26 ± 0.42
Parietal Lobe5.08 ± 0.41
Pontine Tegmentum5.09 ± 0.44
Striatum4.87 ± 0.5
Subthalamus5.44 ± 0.59
Temporal Lobe5.02 ± 0.47
Thalamus5.06 ± 0.38
White Matter4.45 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ndnl2CBCerebellum6.5
7.7
Ndnl2CTXCerebral cortex25.77
20.36
Ndnl2HIPHippocampal region30
48.93
Ndnl2HPFHippocampal formation31.49
40.27
Ndnl2HYHypothalamus5.14
5.89
Ndnl2LSXLateral septal complex2.85
1.9
Ndnl2MBMidbrain6.34
6.61
Ndnl2MYMedulla20.29
24.44
Ndnl2OLFOlfactory bulb24.53
21.44
Ndnl2PPons7.73
9.18
Ndnl2PALPallidum10.94
11.39
Ndnl2RHPRetrohippocampal region34.96
29.87
Ndnl2sAMYStriatum-like amygdalar nuclei13.75
11.59
Ndnl2STRStriatum8.12
6.65
Ndnl2STRdStriatum dorsal region6.87
5.52
Ndnl2STRvStriatum ventral region11.93
9.72
Ndnl2THThalamus12.58
14.12
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018