AutismKB 2.0

Annotation Detail for ZNF253


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Basic Information Top
Gene Symbol:ZNF253 ( BMZF-1,BMZF1,FLJ90391,ZNF411 )
Gene Full Name: zinc finger protein 253
Band: 19p13.11
Quick LinksEntrez ID:56242; OMIM: 606954; Uniprot ID:ZN253_HUMAN; ENSEMBL ID: ENSG00000213988; HGNC ID: 13497
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206900_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts8
Adipocyte6.5
AdrenalCortex8.25
Adrenalgland5.9
Amygdala6.35
Appendix18.9
AtrioventricularNode8.25
BDCA4+_DentriticCells6.6
Bonemarrow6.75
BronchialEpithelialCells5.75
CD105+_Endothelial6.25
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.6
CD33+_Myeloid7.85
CD34+7.55
CD4+_Tcells8.85
CD56+_NKCells7
CD71+_EarlyErythroid6.05
CD8+_Tcells8.45
CardiacMyocytes9.15
Caudatenucleus5.55
Cerebellum5.25
CerebellumPeduncles7.8
CiliaryGanglion7.05
CingulateCortex7
Colorectaladenocarcinoma5.9
DorsalRootGanglion9.7
FetalThyroid6.35
Fetalbrain9.15
Fetalliver6.05
Fetallung5
GlobusPallidus6.65
Heart8.7
Hypothalamus6.65
Kidney5.35
Leukemia_chronicMyelogenousK-5625.75
Leukemia_promyelocytic-HL-605.45
Leukemialymphoblastic(MOLT-4)8.55
Liver8.55
Lung6.4
Lymphnode5.55
Lymphoma_burkitts(Daudi)8.65
Lymphoma_burkitts(Raji)8.4
MedullaOblongata7.3
OccipitalLobe5.7
OlfactoryBulb5.3
Ovary5.15
Pancreas5.4
PancreaticIslet6.85
ParietalLobe7
Pituitary8.05
Placenta5.7
Pons6.15
PrefrontalCortex8.05
Prostate6.95
Salivarygland6.9
SkeletalMuscle16.05
Skin9.55
SmoothMuscle6.95
Spinalcord6.65
SubthalamicNucleus13.55
SuperiorCervicalGanglion56.65
TemporalLobe6.75
Testis5.45
TestisGermCell5.35
TestisIntersitial5.9
TestisLeydigCell7
TestisSeminiferousTubule5.95
Thalamus8.45
Thymus4.75
Thyroid7.15
Tongue9
Tonsil6.45
Trachea5.35
TrigeminalGanglion10.35
Uterus4.55
UterusCorpus12.95
WholeBlood6.8
Wholebrain4.65
colon6.15
pineal_day9.34
pineal_night10.16
retina7.575
small_intestine5.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P165214
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.42 ± 0.12
Basal Forebrain10.33 ± 0.08
Basal Part of Pons10.21 ± 0.12
Cerebellar Cortex10.41 ± 0.2
Cerebellar Nuclei10.26 ± 0.17
Claustrum10.31 ± 0.15
Epithalamus10.38 ± 0.25
Frontal Lobe10.3 ± 0.21
Globus Pallidus10.61 ± 0.21
Hypothalamus10.34 ± 0.23
Insula10.31 ± 0.15
Limbic Lobe10.39 ± 0.2
Mesencephalon10.39 ± 0.21
Myelencephalon10.31 ± 0.2
Occipital Lobe10.25 ± 0.21
Parietal Lobe10.35 ± 0.24
Pontine Tegmentum10.38 ± 0.2
Striatum10.58 ± 0.22
Subthalamus10.36 ± 0.16
Temporal Lobe10.34 ± 0.18
Thalamus10.22 ± 0.21
White Matter10.96 ± 0.1
Mouse Brain ISH
Peptide Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018