AutismKB 2.0

Annotation Detail for MEPCE


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Basic Information Top
Gene Symbol:MEPCE ( BCDIN3,FLJ20257 )
Gene Full Name: methylphosphate capping enzyme
Band: 7q22.1
Quick LinksEntrez ID:56257; OMIM: 611478; Uniprot ID:MEPCE_HUMAN; ENSEMBL ID: ENSG00000146834; HGNC ID: 20247
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst5 / 6231980
fetus37 / 56401265
neonate1 / 3109732
infant0 / 236200 
juvenile5 / 5555689
adult125 / 193912164
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor6 / 34366174
chondrosarcoma2 / 8282324
colorectal tumor15 / 114246131
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor18 / 26384568
glioma10 / 10688393
head and neck tumor17 / 136302124
kidney tumor4 / 6895958
leukemia6 / 9584262
liver tumor3 / 9635931
lung tumor8 / 10312777
lymphoma1 / 7175513
non-neoplasia6 / 9725061
normal178 / 336030752
ovarian tumor10 / 76682130
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer12 / 102680116
retinoblastoma4 / 4635686
skin tumor7 / 12494956
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland6 / 33197180
ascites6 / 40015149
bladder4 / 29757134
blood10 / 12347880
bone4 / 7165555
bone marrow1 / 4880120
brain60 / 110098954
cervix6 / 48171124
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus0 / 202090 
eye9 / 21105442
heart3 / 8962633
intestine23 / 23447298
kidney6 / 21177728
larynx4 / 24145165
liver7 / 20774333
lung16 / 33697447
lymph0 / 442700 
lymph node8 / 9161087
mammary gland5 / 15327132
mouth8 / 67052119
muscle6 / 10771555
nerve0 / 157680 
ovary11 / 102051107
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate19 / 189345100
salivary gland0 / 201550 
skin9 / 21057442
spleen4 / 5395274
stomach1 / 9661910
testis33 / 33044299
thymus3 / 8113136
thyroid10 / 47473210
tonsil2 / 16999117
trachea3 / 5241357
umbilical cord0 / 136800 
uterus21 / 23287890
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219798_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts324.85
Adipocyte61.35
AdrenalCortex86.25
Adrenalgland114.15
Amygdala71.3
Appendix61.4
AtrioventricularNode41.15
BDCA4+_DentriticCells162.8
Bonemarrow64.9
BronchialEpithelialCells39.8
CD105+_Endothelial469.05
CD14+_Monocytes139.55
CD19+_BCells(neg._sel.)408.8
CD33+_Myeloid240.5
CD34+281.6
CD4+_Tcells143.9
CD56+_NKCells257.2
CD71+_EarlyErythroid86.5
CD8+_Tcells106.55
CardiacMyocytes88.5
Caudatenucleus59.75
Cerebellum84.15
CerebellumPeduncles80.45
CiliaryGanglion41.6
CingulateCortex62.8
Colorectaladenocarcinoma442.1
DorsalRootGanglion45.45
FetalThyroid111
Fetalbrain62.4
Fetalliver65.2
Fetallung57.5
GlobusPallidus44.45
Heart177.2
Hypothalamus74
Kidney71.85
Leukemia_chronicMyelogenousK-56280.55
Leukemia_promyelocytic-HL-6059.1
Leukemialymphoblastic(MOLT-4)118.1
Liver118.95
Lung96.75
Lymphnode58.35
Lymphoma_burkitts(Daudi)134.4
Lymphoma_burkitts(Raji)78.5
MedullaOblongata55.25
OccipitalLobe56.8
OlfactoryBulb52.05
Ovary40
Pancreas68.6
PancreaticIslet98.3
ParietalLobe64.95
Pituitary71.8
Placenta160
Pons58.45
PrefrontalCortex78.6
Prostate96.15
Salivarygland34.65
SkeletalMuscle67.15
Skin46.1
SmoothMuscle81.85
Spinalcord102.5
SubthalamicNucleus55.6
SuperiorCervicalGanglion62.7
TemporalLobe56.7
Testis575.35
TestisGermCell290
TestisIntersitial180.35
TestisLeydigCell108.75
TestisSeminiferousTubule139.85
Thalamus69.75
Thymus154.7
Thyroid260
Tongue64.75
Tonsil64
Trachea71.25
TrigeminalGanglion59.65
Uterus85.15
UterusCorpus54.45
WholeBlood105.15
Wholebrain107.15
colon61.85
pineal_day126.54
pineal_night164.24
retina264.525
small_intestine59.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P312189
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.44 ± 0.29
Basal Forebrain5.52 ± 0.11
Basal Part of Pons5.59 ± 0.32
Cerebellar Cortex5.67 ± 0.22
Cerebellar Nuclei5.47 ± 0.25
Claustrum5.57 ± 0.51
Epithalamus5.92 ± 0.28
Frontal Lobe5.44 ± 0.3
Globus Pallidus5.32 ± 0.38
Hypothalamus5.55 ± 0.28
Insula5.41 ± 0.31
Limbic Lobe5.51 ± 0.36
Mesencephalon5.47 ± 0.37
Myelencephalon5.48 ± 0.39
Occipital Lobe5.7 ± 0.42
Parietal Lobe5.52 ± 0.28
Pontine Tegmentum5.5 ± 0.33
Striatum5.79 ± 0.31
Subthalamus5.16 ± 0.61
Temporal Lobe5.37 ± 0.31
Thalamus5.54 ± 0.43
White Matter5.38 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Bcdin3CBCerebellum2.89
3.39
Bcdin3CTXCerebral cortex2.99
2.59
Bcdin3HIPHippocampal region13.24
13.52
Bcdin3HPFHippocampal formation12.34
11.91
Bcdin3HYHypothalamus7.77
7.7
Bcdin3LSXLateral septal complex0.46
0.56
Bcdin3MBMidbrain1.11
1.73
Bcdin3MYMedulla3.17
4.6
Bcdin3OLFOlfactory bulb17.47
15.03
Bcdin3PPons8.95
12.03
Bcdin3PALPallidum5.24
4.87
Bcdin3RHPRetrohippocampal region10.57
9.41
Bcdin3sAMYStriatum-like amygdalar nuclei11.45
8.03
Bcdin3STRStriatum6.82
5.31
Bcdin3STRdStriatum dorsal region2.89
2.27
Bcdin3STRvStriatum ventral region19.77
14.46
Bcdin3THThalamus0.89
0.78
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00065002 24 234 257 DITDPLSLNTCTDEGHVVLASPLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018