AutismKB 2.0

Annotation Detail for CPXM1


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Basic Information Top
Gene Symbol:CPXM1 ( CPX1,CPXM )
Gene Full Name: carboxypeptidase X (M14 family), member 1
Band: 20p13
Quick LinksEntrez ID:56265; OMIM: 609555; Uniprot ID:CPXM1_HUMAN; ENSEMBL ID: ENSG00000088882; HGNC ID: 15771
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst6 / 6231996
fetus20 / 56401235
neonate1 / 3109732
infant1 / 2362042
juvenile4 / 5555671
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor20 / 26384575
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma6 / 7175583
non-neoplasia1 / 9725010
normal70 / 336030720
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow3 / 4880161
brain17 / 110098915
cervix1 / 4817120
connective tissue1 / 1492556
ear1 / 1621261
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye3 / 21105414
heart2 / 8962622
intestine0 / 2344720 
kidney5 / 21177723
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth2 / 6705229
muscle0 / 1077150 
nerve1 / 1576863
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta20 / 28082571
prostate0 / 1893450 
salivary gland2 / 2015599
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis14 / 33044242
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus18 / 23287877
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1728_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.94 ± 1.01
Basal Forebrain1.53 ± 0.25
Basal Part of Pons1.2 ± 0.35
Cerebellar Cortex1.33 ± 0.7
Cerebellar Nuclei1.76 ± 0.69
Claustrum2.36 ± 0.86
Epithalamus1.48 ± 0.96
Frontal Lobe1.35 ± 0.6
Globus Pallidus2.31 ± 0.48
Hypothalamus1.57 ± 0.68
Insula1.39 ± 0.52
Limbic Lobe1.53 ± 0.62
Mesencephalon1.63 ± 0.69
Myelencephalon1.54 ± 0.65
Occipital Lobe1.57 ± 0.73
Parietal Lobe1.54 ± 0.69
Pontine Tegmentum1.62 ± 0.72
Striatum1.71 ± 0.53
Subthalamus1.62 ± 0.61
Temporal Lobe1.41 ± 0.6
Thalamus1.47 ± 0.57
White Matter2.11 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cpxm1CBCerebellum1.55
1.69
Cpxm1CTXCerebral cortex1.98
1.66
Cpxm1HIPHippocampal region0.58
0.69
Cpxm1HPFHippocampal formation0.52
0.66
Cpxm1HYHypothalamus1.28
1.39
Cpxm1LSXLateral septal complex1.03
0.6
Cpxm1MBMidbrain1.87
1.92
Cpxm1MYMedulla4.65
4.98
Cpxm1OLFOlfactory bulb3.15
1.95
Cpxm1PPons5.19
4.02
Cpxm1PALPallidum0.33
0.15
Cpxm1RHPRetrohippocampal region0.4
0.56
Cpxm1sAMYStriatum-like amygdalar nuclei0.19
0.18
Cpxm1STRStriatum0.39
0.28
Cpxm1STRdStriatum dorsal region0.37
0.28
Cpxm1STRvStriatum ventral region0.41
0.26
Cpxm1THThalamus1.48
1.73
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018