AutismKB 2.0

Annotation Detail for PARD3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PARD3 ( ASIP,Baz,Bazooka,FLJ21015,PAR3,PAR3alpha,PARD3A,SE2-5L16,SE2-5LT1,SE2-5T2 )
Gene Full Name: par-3 partitioning defective 3 homolog (C. elegans)
Band: 10p11.22-p11.21
Quick LinksEntrez ID:56288; OMIM: 606745; Uniprot ID:PARD3_HUMAN; ENSEMBL ID: ENSG00000148498; HGNC ID: 16051
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult95 / 193912148
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor17 / 26384564
glioma8 / 10688374
head and neck tumor18 / 136302132
kidney tumor6 / 6895987
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal112 / 336030733
ovarian tumor7 / 7668291
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites5 / 40015124
bladder3 / 29757100
blood1 / 1234788
bone6 / 7165583
bone marrow2 / 4880140
brain21 / 110098919
cervix1 / 4817120
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye22 / 211054104
heart4 / 8962644
intestine10 / 23447242
kidney16 / 21177775
larynx3 / 24145124
liver3 / 20774314
lung18 / 33697453
lymph0 / 442700 
lymph node1 / 9161010
mammary gland10 / 15327165
mouth7 / 67052104
muscle3 / 10771527
nerve1 / 1576863
ovary10 / 10205197
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta6 / 28082521
prostate3 / 18934515
salivary gland1 / 2015549
skin8 / 21057437
spleen5 / 5395292
stomach3 / 9661931
testis8 / 33044224
thymus1 / 8113112
thyroid5 / 47473105
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221527_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.95
Adipocyte5.6
AdrenalCortex5.9
Adrenalgland4.7
Amygdala6
Appendix5.65
AtrioventricularNode4.3
BDCA4+_DentriticCells5.9
Bonemarrow5.55
BronchialEpithelialCells5.35
CD105+_Endothelial5.7
CD14+_Monocytes6.05
CD19+_BCells(neg._sel.)5.9
CD33+_Myeloid7.35
CD34+6.75
CD4+_Tcells6.25
CD56+_NKCells6.45
CD71+_EarlyErythroid5.15
CD8+_Tcells5.3
CardiacMyocytes7.2
Caudatenucleus5.1
Cerebellum4.55
CerebellumPeduncles6.4
CiliaryGanglion3.95
CingulateCortex5.7
Colorectaladenocarcinoma5.65
DorsalRootGanglion4.4
FetalThyroid7.15
Fetalbrain5.65
Fetalliver4.85
Fetallung5.4
GlobusPallidus4.15
Heart7.2
Hypothalamus6.3
Kidney4.55
Leukemia_chronicMyelogenousK-5625.15
Leukemia_promyelocytic-HL-605
Leukemialymphoblastic(MOLT-4)4.55
Liver7.5
Lung6.35
Lymphnode4.9
Lymphoma_burkitts(Daudi)7.15
Lymphoma_burkitts(Raji)7.85
MedullaOblongata5.1
OccipitalLobe5.05
OlfactoryBulb5.8
Ovary3.75
Pancreas4.55
PancreaticIslet6.05
ParietalLobe5.9
Pituitary6.6
Placenta5.85
Pons5.5
PrefrontalCortex7.75
Prostate6.7
Salivarygland4.65
SkeletalMuscle6.6
Skin5.8
SmoothMuscle6.35
Spinalcord6.1
SubthalamicNucleus5.2
SuperiorCervicalGanglion6.4
TemporalLobe5.15
Testis4.95
TestisGermCell4.85
TestisIntersitial4.75
TestisLeydigCell5.6
TestisSeminiferousTubule4.9
Thalamus5.75
Thymus4.45
Thyroid7.25
Tongue5.6
Tonsil5.55
Trachea4.75
TrigeminalGanglion6.35
Uterus8.35
UterusCorpus5.1
WholeBlood5.8
Wholebrain4.65
colon5.75
pineal_day7.16
pineal_night6.96
retina7.575
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13906_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6 ± 0.54
Basal Forebrain6.12 ± 0.2
Basal Part of Pons4.67 ± 0.5
Cerebellar Cortex5.13 ± 0.28
Cerebellar Nuclei5.37 ± 0.7
Claustrum5.08 ± 0.73
Epithalamus6.52 ± 0.26
Frontal Lobe5.49 ± 0.51
Globus Pallidus7.52 ± 0.57
Hypothalamus6.23 ± 0.37
Insula5.6 ± 0.55
Limbic Lobe5.72 ± 0.79
Mesencephalon5.97 ± 0.61
Myelencephalon5.79 ± 0.58
Occipital Lobe5.77 ± 0.56
Parietal Lobe5.86 ± 0.68
Pontine Tegmentum6.1 ± 0.43
Striatum6.95 ± 0.7
Subthalamus5.65 ± 0.56
Temporal Lobe5.64 ± 0.45
Thalamus5.77 ± 0.38
White Matter5.73 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pard3CBCerebellum2.65
3.4
Pard3CTXCerebral cortex7.97
6.44
Pard3HIPHippocampal region20.45
26.67
Pard3HPFHippocampal formation16.65
19.17
Pard3HYHypothalamus6.86
5.66
Pard3LSXLateral septal complex8.09
5.7
Pard3MBMidbrain6.28
6.4
Pard3MYMedulla4.71
5.75
Pard3OLFOlfactory bulb8.78
7.35
Pard3PPons4.2
4.53
Pard3PALPallidum9.1
7.75
Pard3RHPRetrohippocampal region11.55
10.54
Pard3sAMYStriatum-like amygdalar nuclei12.67
8.94
Pard3STRStriatum46.94
32.7
Pard3STRdStriatum dorsal region57.01
39.98
Pard3STRvStriatum ventral region47.6
32.09
Pard3THThalamus10.05
9
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PARD3_HUMAN_336 10 336 345 RFEQAQHMFR PRIDE
PARD3_HUMAN_337 9 337 345 FEQAQHMFR PRIDE
PARD3_HUMAN_547 8 547 554 QEDAFHPR PRIDE
PAp00497397 26 886 911 SYDKPAVDDDDEGMETLEEDTEESSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved