AutismKB 2.0

Annotation Detail for AZGP1


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Basic Information Top
Gene Symbol:AZGP1 ( ZA2G,ZAG )
Gene Full Name: alpha-2-glycoprotein 1, zinc-binding
Band: 7q22.1
Quick LinksEntrez ID:563; OMIM: 194460; Uniprot ID:ZA2G_HUMAN; ENSEMBL ID: ENSG00000160862; HGNC ID: 910
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus33 / 56401258
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult216 / 1939121111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor33 / 96359342
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal242 / 336030772
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder2 / 2975767
blood0 / 1234780 
bone4 / 7165555
bone marrow1 / 4880120
brain5 / 11009894
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye39 / 211054184
heart10 / 89626111
intestine18 / 23447276
kidney9 / 21177742
larynx1 / 2414541
liver94 / 207743452
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland39 / 153271254
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate59 / 189345311
salivary gland5 / 20155248
skin11 / 21057452
spleen0 / 539520 
stomach6 / 9661962
testis4 / 33044212
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209309_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.7
Adipocyte119.8
AdrenalCortex13
Adrenalgland8
Amygdala8
Appendix10.2
AtrioventricularNode42.05
BDCA4+_DentriticCells7.7
Bonemarrow9.7
BronchialEpithelialCells7.95
CD105+_Endothelial8.35
CD14+_Monocytes9.15
CD19+_BCells(neg._sel.)8.45
CD33+_Myeloid10.15
CD34+9.8
CD4+_Tcells8.2
CD56+_NKCells9.15
CD71+_EarlyErythroid8.5
CD8+_Tcells7.35
CardiacMyocytes16
Caudatenucleus8.65
Cerebellum7
CerebellumPeduncles11.35
CiliaryGanglion18
CingulateCortex9.1
Colorectaladenocarcinoma8.4
DorsalRootGanglion80.85
FetalThyroid8.85
Fetalbrain7.95
Fetalliver279.25
Fetallung145.65
GlobusPallidus6.95
Heart69.45
Hypothalamus8.6
Kidney246.1
Leukemia_chronicMyelogenousK-5627.55
Leukemia_promyelocytic-HL-607.35
Leukemialymphoblastic(MOLT-4)6.35
Liver5367.45
Lung40.8
Lymphnode6.45
Lymphoma_burkitts(Daudi)12.1
Lymphoma_burkitts(Raji)17.45
MedullaOblongata7.45
OccipitalLobe7.45
OlfactoryBulb546
Ovary10.6
Pancreas502.2
PancreaticIslet910.2
ParietalLobe9.75
Pituitary9.75
Placenta8.15
Pons9.4
PrefrontalCortex18.6
Prostate5895.75
Salivarygland2376
SkeletalMuscle14.1
Skin115.55
SmoothMuscle10.2
Spinalcord9.55
SubthalamicNucleus15.5
SuperiorCervicalGanglion15.1
TemporalLobe8.55
Testis12.65
TestisGermCell17.8
TestisIntersitial12
TestisLeydigCell9.65
TestisSeminiferousTubule8.15
Thalamus10.85
Thymus6.35
Thyroid10.2
Tongue13.25
Tonsil8.65
Trachea2525.05
TrigeminalGanglion12
Uterus6.35
UterusCorpus8.95
WholeBlood9
Wholebrain6.5
colon9.1
pineal_day9.94
pineal_night9.92
retina11.65
small_intestine25.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P71268
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.73 ± 0.74
Basal Forebrain4.64 ± 0.59
Basal Part of Pons4.98 ± 1.02
Cerebellar Cortex3.57 ± 0.67
Cerebellar Nuclei5.66 ± 0.65
Claustrum3.79 ± 0.79
Epithalamus3.89 ± 1.43
Frontal Lobe4.41 ± 0.87
Globus Pallidus6.56 ± 0.56
Hypothalamus3.65 ± 1.12
Insula3.76 ± 0.6
Limbic Lobe3.9 ± 0.94
Mesencephalon4.73 ± 1
Myelencephalon4.3 ± 0.97
Occipital Lobe4.76 ± 0.95
Parietal Lobe4.35 ± 0.88
Pontine Tegmentum4.53 ± 0.98
Striatum5.63 ± 0.84
Subthalamus4.5 ± 0.89
Temporal Lobe4.1 ± 0.76
Thalamus5.08 ± 0.56
White Matter6.78 ± 1.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Azgp1CBCerebellum22.69
28.71
Azgp1CTXCerebral cortex23.4
15.42
Azgp1HIPHippocampal region16.4
18.41
Azgp1HPFHippocampal formation19.59
17.89
Azgp1HYHypothalamus13.17
10.08
Azgp1LSXLateral septal complex6.63
5.95
Azgp1MBMidbrain11.79
9.95
Azgp1MYMedulla19.41
18.57
Azgp1OLFOlfactory bulb36.98
27.32
Azgp1PPons18.39
16
Azgp1PALPallidum14.94
11.64
Azgp1RHPRetrohippocampal region24.38
17
Azgp1sAMYStriatum-like amygdalar nuclei16.53
10.34
Azgp1STRStriatum17.94
12.35
Azgp1STRdStriatum dorsal region15.43
10.95
Azgp1STRvStriatum ventral region32.53
20.23
Azgp1THThalamus16.18
12.34
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024126 14 178 191 AKAYLEEECPATLR Peptide Atlas
ZA2G_HUMAN_147 16 147 162 EIPAWVPFDPAAQITK PRIDE
ZA2G_HUMAN_177 12 177 188 AYLEEECPATLR PRIDE
ZA2G_HUMAN_239 10 239 248 AGEVQEPELR PRIDE
ZA2G_HUMAN_25 12 25 36 YSLTYIYTGLSK PRIDE
ZA2G_HUMAN_37 21 37 57 HVEDVPAFQALGSLNDLQFFR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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