AutismKB 2.0

Annotation Detail for PRSS2


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Basic Information Top
Gene Symbol:PRSS2 ( MGC111183,MGC120174,MGC120175,TRY2,TRY8,TRYP2 )
Gene Full Name: protease, serine, 2 (trypsin 2)
Band: 7q34
Quick LinksEntrez ID:5645; OMIM: 601564; Uniprot ID:TRY2_HUMAN; ENSEMBL ID: ENSG00000204983; HGNC ID: 9483
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11091_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.33 ± 0.79
Basal Forebrain6.95 ± 0.55
Basal Part of Pons6.7 ± 0.66
Cerebellar Cortex6.59 ± 0.49
Cerebellar Nuclei6.77 ± 0.42
Claustrum7.6 ± 0.62
Epithalamus6.23 ± 1.09
Frontal Lobe6.78 ± 0.61
Globus Pallidus7.07 ± 0.61
Hypothalamus6.84 ± 0.35
Insula6.69 ± 0.57
Limbic Lobe6.95 ± 0.62
Mesencephalon7 ± 0.6
Myelencephalon6.89 ± 0.61
Occipital Lobe6.86 ± 0.67
Parietal Lobe6.82 ± 0.57
Pontine Tegmentum6.6 ± 0.47
Striatum6.93 ± 0.64
Subthalamus6.37 ± 1.3
Temporal Lobe6.79 ± 0.67
Thalamus6.72 ± 0.58
White Matter6.6 ± 0.54
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00080430 13 80 92 VLEGNEQFINAAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018