AutismKB 2.0

Annotation Detail for RELN


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Basic Information Top
Gene Symbol:RELN ( PRO1598,RL )
Gene Full Name: reelin
Band: 7q22.1
Quick LinksEntrez ID:5649; OMIM: 600514; Uniprot ID:RELN_HUMAN; ENSEMBL ID: ENSG00000189056; HGNC ID: 9957
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult33 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal127 / 336030737
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow1 / 4880120
brain80 / 110098972
cervix0 / 481710 
connective tissue2 / 14925513
ear11 / 16212678
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye7 / 21105433
heart2 / 8962622
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea10 / 52413190
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205923_at
Cell line Expression level Expression bar
721_B_lymphoblasts27.3
Adipocyte37.2
AdrenalCortex54.55
Adrenalgland32.1
Amygdala118.4
Appendix114.2
AtrioventricularNode194.75
BDCA4+_DentriticCells22.75
Bonemarrow39.15
BronchialEpithelialCells26.95
CD105+_Endothelial31.25
CD14+_Monocytes17.2
CD19+_BCells(neg._sel.)31
CD33+_Myeloid27.5
CD34+26.3
CD4+_Tcells21.25
CD56+_NKCells32.95
CD71+_EarlyErythroid32.2
CD8+_Tcells24.7
CardiacMyocytes36.8
Caudatenucleus83.1
Cerebellum336.8
CerebellumPeduncles1489.95
CiliaryGanglion128.4
CingulateCortex54.7
Colorectaladenocarcinoma23.55
DorsalRootGanglion278.4
FetalThyroid45.15
Fetalbrain93.35
Fetalliver283.35
Fetallung33.6
GlobusPallidus29.8
Heart39.45
Hypothalamus86.7
Kidney33.65
Leukemia_chronicMyelogenousK-56251.5
Leukemia_promyelocytic-HL-6032.95
Leukemialymphoblastic(MOLT-4)34.25
Liver45.55
Lung31.1
Lymphnode34.25
Lymphoma_burkitts(Daudi)48.15
Lymphoma_burkitts(Raji)45.3
MedullaOblongata66.05
OccipitalLobe65
OlfactoryBulb784.15
Ovary35.6
Pancreas30.4
PancreaticIslet38.9
ParietalLobe58.05
Pituitary44.6
Placenta36.75
Pons81.25
PrefrontalCortex84.45
Prostate38.5
Salivarygland45.35
SkeletalMuscle44.15
Skin42.85
SmoothMuscle31.9
Spinalcord89.85
SubthalamicNucleus50.7
SuperiorCervicalGanglion316.95
TemporalLobe66.85
Testis31.8
TestisGermCell38.75
TestisIntersitial31.45
TestisLeydigCell38.15
TestisSeminiferousTubule32.7
Thalamus47.8
Thymus25
Thyroid53.1
Tongue45.7
Tonsil39.2
Trachea37.1
TrigeminalGanglion139.9
Uterus29.35
UterusCorpus28.15
WholeBlood26.35
Wholebrain34.85
colon28.25
pineal_day804.26
pineal_night477.32
retina58.95
small_intestine27.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_536_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.29 ± 1.33
Basal Forebrain2.96 ± 0.54
Basal Part of Pons2.41 ± 0.6
Cerebellar Cortex4.07 ± 0.66
Cerebellar Nuclei3.02 ± 0.88
Claustrum3.68 ± 0.89
Epithalamus2.38 ± 1.04
Frontal Lobe2.74 ± 1.14
Globus Pallidus1.89 ± 0.58
Hypothalamus3.11 ± 0.98
Insula3.2 ± 1.06
Limbic Lobe3.01 ± 1.12
Mesencephalon3.12 ± 0.88
Myelencephalon2.94 ± 0.87
Occipital Lobe2.68 ± 0.85
Parietal Lobe2.52 ± 0.97
Pontine Tegmentum2.92 ± 1.2
Striatum2.94 ± 1.09
Subthalamus2.89 ± 0.91
Temporal Lobe2.8 ± 0.89
Thalamus2.8 ± 0.96
White Matter2.11 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
RelnCBCerebellum50
50
RelnCTXCerebral cortex10.69
16.35
RelnHIPHippocampal region8.77
18.32
RelnHPFHippocampal formation11.14
20.54
RelnHYHypothalamus6.85
8.04
RelnLSXLateral septal complex10.61
11.59
RelnMBMidbrain8.99
11.24
RelnMYMedulla8.78
11.81
RelnOLFOlfactory bulb28.01
49.8
RelnPPons5
6.16
RelnPALPallidum8.97
11.94
RelnRHPRetrohippocampal region16.34
25.31
RelnsAMYStriatum-like amygdalar nuclei11.83
17.73
RelnSTRStriatum32.23
32.27
RelnSTRdStriatum dorsal region46.91
46.9
RelnSTRvStriatum ventral region18.39
15.62
RelnTHThalamus2.75
3.27
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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