Annotation Detail for PRSS8
Basic Information Top
| Gene Symbol: | PRSS8 ( CAP1,PROSTASIN ) |
|---|---|
| Gene Full Name: | protease, serine, 8 |
| Band: | 16p11.2 |
| Quick Links | Entrez ID:5652; OMIM: 600823; Uniprot ID:PRSS8_HUMAN; ENSEMBL ID: ENSG00000052344; HGNC ID: 9491 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.75799
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 7 / 70761 | 98 |  |
| blastocyst | 6 / 62319 | 96 | |
| fetus | 29 / 564012 | 51 | |
| neonate | 1 / 31097 | 32 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 232 / 1939121 | 119 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 37 / 94178 | 392 |  |
| cervical tumor | 10 / 34366 | 290 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 34 / 114246 | 297 | |
| esophageal tumor | 11 / 17290 | 636 | |
| gastrointestinal tumor | 27 / 119369 | 226 | |
| germ cell tumor | 17 / 263845 | 64 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 9 / 103127 | 87 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 5 / 97250 | 51 | |
| normal | 313 / 3360307 | 93 | |
| ovarian tumor | 7 / 76682 | 91 | |
| pancreatic tumor | 10 / 104616 | 95 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 25 / 90257 | 276 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 10 / 40015 | 249 | |
| bladder | 16 / 29757 | 537 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 10 / 1100989 | 9 |  |
| cervix | 10 / 48171 | 207 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 15 / 215722 | 69 | |
| esophagus | 12 / 20209 | 593 | |
| eye | 3 / 211054 | 14 | |
| heart | 0 / 89626 | 0 | |
| intestine | 119 / 234472 | 507 | |
| kidney | 41 / 211777 | 193 | |
| larynx | 1 / 24145 | 41 | |
| liver | 1 / 207743 | 4 | |
| lung | 39 / 336974 | 115 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 46 / 153271 | 300 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 9 / 102051 | 88 | |
| pancreas | 19 / 214812 | 88 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 102 / 280825 | 363 | |
| prostate | 22 / 189345 | 116 | |
| salivary gland | 6 / 20155 | 297 | |
| skin | 4 / 210574 | 18 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 39 / 96619 | 403 | |
| testis | 8 / 330442 | 24 | |
| thymus | 19 / 81131 | 234 | |
| thyroid | 8 / 47473 | 168 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 15 / 52413 | 286 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 29 / 232878 | 124 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202525_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.35 | |
| Adipocyte | 4.45 | |
| AdrenalCortex | 4.75 | |
| Adrenalgland | 3.75 | |
| Amygdala | 4.65 | |
| Appendix | 4.7 | |
| AtrioventricularNode | 3.45 | |
| BDCA4+_DentriticCells | 4.65 | |
| Bonemarrow | 4.45 | |
| BronchialEpithelialCells | 25.15 | |
| CD105+_Endothelial | 4.45 | |
| CD14+_Monocytes | 4.7 | |
| CD19+_BCells(neg._sel.) | 4.7 | |
| CD33+_Myeloid | 5.55 | |
| CD34+ | 5.65 | |
| CD4+_Tcells | 4.75 | |
| CD56+_NKCells | 5.25 | |
| CD71+_EarlyErythroid | 4.2 | |
| CD8+_Tcells | 4.2 | |
| CardiacMyocytes | 5.7 | |
| Caudatenucleus | 4 | |
| Cerebellum | 3.65 | |
| CerebellumPeduncles | 5.1 | |
| CiliaryGanglion | 3.1 | |
| CingulateCortex | 4.55 | |
| Colorectaladenocarcinoma | 4.45 | |
| DorsalRootGanglion | 3.35 | |
| FetalThyroid | 4.65 | |
| Fetalbrain | 4.35 | |
| Fetalliver | 3.85 | |
| Fetallung | 13.65 | |
| GlobusPallidus | 3.25 | |
| Heart | 5.7 | |
| Hypothalamus | 4.9 | |
| Kidney | 5.2 | |
| Leukemia_chronicMyelogenousK-562 | 4.05 | |
| Leukemia_promyelocytic-HL-60 | 3.95 | |
| Leukemialymphoblastic(MOLT-4) | 3.55 | |
| Liver | 6.1 | |
| Lung | 47.95 | |
| Lymphnode | 3.85 | |
| Lymphoma_burkitts(Daudi) | 5.65 | |
| Lymphoma_burkitts(Raji) | 6.2 | |
| MedullaOblongata | 4.1 | |
| OccipitalLobe | 4 | |
| OlfactoryBulb | 3.55 | |
| Ovary | 3 | |
| Pancreas | 6.1 | |
| PancreaticIslet | 5.85 | |
| ParietalLobe | 4.7 | |
| Pituitary | 5.25 | |
| Placenta | 149.2 | |
| Pons | 4.2 | |
| PrefrontalCortex | 5.45 | |
| Prostate | 88.25 | |
| Salivarygland | 3.95 | |
| SkeletalMuscle | 5.1 | |
| Skin | 3.5 | |
| SmoothMuscle | 5.05 | |
| Spinalcord | 4.75 | |
| SubthalamicNucleus | 4.05 | |
| SuperiorCervicalGanglion | 5.25 | |
| TemporalLobe | 4.05 | |
| Testis | 3.8 | |
| TestisGermCell | 3.7 | |
| TestisIntersitial | 3.75 | |
| TestisLeydigCell | 4.4 | |
| TestisSeminiferousTubule | 3.8 | |
| Thalamus | 4.55 | |
| Thymus | 3.75 | |
| Thyroid | 67.75 | |
| Tongue | 4.5 | |
| Tonsil | 4.5 | |
| Trachea | 10.7 | |
| TrigeminalGanglion | 4.45 | |
| Uterus | 3.65 | |
| UterusCorpus | 4.05 | |
| WholeBlood | 4.9 | |
| Wholebrain | 3.75 | |
| colon | 39.1 | |
| pineal_day | 5.58 | |
| pineal_night | 5.44 | |
| retina | 5.375 | |
| small_intestine | 12.15 | |
- Probe name: CUST_16073_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.89 ± 0.72 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.57 ± 0.74 | |
| Basal Part of Pons | 4.27 ± 0.52 | |
| Cerebellar Cortex | 3.48 ± 0.56 | |
| Cerebellar Nuclei | 4.32 ± 0.45 | |
| Claustrum | 4.09 ± 0.57 | |
| Epithalamus | 3.25 ± 0.93 | |
| Frontal Lobe | 3.99 ± 0.66 | |
| Globus Pallidus | 4.2 ± 0.7 | |
| Hypothalamus | 3.85 ± 0.76 | |
| Insula | 3.71 ± 0.49 | |
| Limbic Lobe | 3.84 ± 0.5 | |
| Mesencephalon | 3.79 ± 0.69 | |
| Myelencephalon | 3.82 ± 0.65 | |
| Occipital Lobe | 3.65 ± 0.63 | |
| Parietal Lobe | 3.89 ± 0.62 | |
| Pontine Tegmentum | 3.71 ± 0.67 | |
| Striatum | 3.72 ± 0.52 | |
| Subthalamus | 4.06 ± 0.54 | |
| Temporal Lobe | 3.81 ± 0.69 | |
| Thalamus | 3.98 ± 0.55 | |
| White Matter | 3.3 ± 0.76 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Prss8 | CB | Cerebellum | 3.59 | |
| 6.77 | | |||
| Prss8 | CTX | Cerebral cortex | 1.7 | |
| 1.83 | | |||
| Prss8 | HIP | Hippocampal region | 3.64 | |
| 3.96 | | |||
| Prss8 | HPF | Hippocampal formation | 2.69 | |
| 2.82 | | |||
| Prss8 | HY | Hypothalamus | 0.63 | |
| 0.68 | | |||
| Prss8 | LSX | Lateral septal complex | 5.24 | |
| 7.37 | | |||
| Prss8 | MB | Midbrain | 0.58 | |
| 1.16 | | |||
| Prss8 | MY | Medulla | 0.17 | |
| 0.29 | | |||
| Prss8 | OLF | Olfactory bulb | 2.43 | |
| 1.86 | | |||
| Prss8 | P | Pons | 0.31 | |
| 0.79 | | |||
| Prss8 | PAL | Pallidum | 0.66 | |
| 0.56 | | |||
| Prss8 | RHP | Retrohippocampal region | 1.16 | |
| 1.25 | | |||
| Prss8 | sAMY | Striatum-like amygdalar nuclei | 2.05 | |
| 1.99 | | |||
| Prss8 | STR | Striatum | 1.49 | |
| 1.72 | | |||
| Prss8 | STRd | Striatum dorsal region | 0.77 | |
| 0.98 | | |||
| Prss8 | STRv | Striatum ventral region | 0.82 | |
| 0.57 | | |||
| Prss8 | TH | Thalamus | 0.81 | |
| 1.02 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00132624 | 14 | 100 | 113 | LGAHQLDSYSEDAK | Peptide Atlas |