AutismKB 2.0

Annotation Detail for MMP26


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Basic Information Top
Gene Symbol:MMP26 ( MGC126590,MGC126592 )
Gene Full Name: matrix metallopeptidase 26
Band: 11p15.4
Quick LinksEntrez ID:56547; OMIM: 605470; Uniprot ID:MMP26_HUMAN; ENSEMBL ID: ENSG00000167346; HGNC ID: 14249
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult6 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal2 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220541_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.25
Adipocyte3.35
AdrenalCortex3.55
Adrenalgland2.85
Amygdala3.55
Appendix3.55
AtrioventricularNode2.65
BDCA4+_DentriticCells3.7
Bonemarrow3.25
BronchialEpithelialCells3.35
CD105+_Endothelial3.4
CD14+_Monocytes3.6
CD19+_BCells(neg._sel.)3.6
CD33+_Myeloid4.35
CD34+4.35
CD4+_Tcells3.7
CD56+_NKCells4.05
CD71+_EarlyErythroid3.15
CD8+_Tcells3.3
CardiacMyocytes4.3
Caudatenucleus3.05
Cerebellum3.1
CerebellumPeduncles3.85
CiliaryGanglion2.4
CingulateCortex3.45
Colorectaladenocarcinoma3.4
DorsalRootGanglion4.4
FetalThyroid3.25
Fetalbrain3.4
Fetalliver2.95
Fetallung2.8
GlobusPallidus3.6
Heart4.25
Hypothalamus3.7
Kidney2.7
Leukemia_chronicMyelogenousK-5623.05
Leukemia_promyelocytic-HL-603
Leukemialymphoblastic(MOLT-4)2.7
Liver4.6
Lung3.7
Lymphnode2.9
Lymphoma_burkitts(Daudi)4.3
Lymphoma_burkitts(Raji)4.7
MedullaOblongata3.1
OccipitalLobe3.05
OlfactoryBulb2.7
Ovary2.25
Pancreas2.7
PancreaticIslet3.6
ParietalLobe5.05
Pituitary3.95
Placenta3.5
Pons3.2
PrefrontalCortex4.25
Prostate3.95
Salivarygland2.7
SkeletalMuscle7.7
Skin2.75
SmoothMuscle3.85
Spinalcord3.6
SubthalamicNucleus3.1
SuperiorCervicalGanglion4
TemporalLobe3.1
Testis2.9
TestisGermCell2.8
TestisIntersitial2.8
TestisLeydigCell3.35
TestisSeminiferousTubule3.45
Thalamus3.45
Thymus2.7
Thyroid4.25
Tongue3.3
Tonsil3.3
Trachea2.8
TrigeminalGanglion3.3
Uterus2.85
UterusCorpus3.05
WholeBlood3.75
Wholebrain2.85
colon3.4
pineal_day4.24
pineal_night4.16
retina4.425
small_intestine3.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15068_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.16 ± 0.97
Basal Forebrain1.76 ± 0.19
Basal Part of Pons1.47 ± 0.43
Cerebellar Cortex1.58 ± 0.69
Cerebellar Nuclei2.03 ± 0.71
Claustrum2.61 ± 0.85
Epithalamus1.47 ± 0.7
Frontal Lobe1.58 ± 0.56
Globus Pallidus2.37 ± 0.33
Hypothalamus1.95 ± 0.81
Insula1.68 ± 0.56
Limbic Lobe1.75 ± 0.59
Mesencephalon1.91 ± 0.67
Myelencephalon1.78 ± 0.63
Occipital Lobe1.79 ± 0.51
Parietal Lobe1.77 ± 0.77
Pontine Tegmentum1.82 ± 0.68
Striatum1.97 ± 0.55
Subthalamus1.89 ± 0.62
Temporal Lobe1.62 ± 0.57
Thalamus1.7 ± 0.52
White Matter2.34 ± 0.35
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018